公开(公告)号：US20070107200A1

公开(公告)日：2007-05-17

申请号：US11556378

申请日：2006-11-03

申请人： Tahseen Chowdhury ,  Edward Gabrielski ,  Christopher Baker

发明人： Tahseen Chowdhury ,  Edward Gabrielski ,  Christopher Baker

IPC分类号： B23P11/00

CPC分类号： A23G3/125 ,  A61J7/003 ,  A61K9/0056 ,  A61K9/2031 ,  A61K9/2095 ,  B29C65/645 ,  B29C65/7841 ,  B29C66/126 ,  B29C66/534 ,  B29C66/71 ,  B29C66/73773 ,  B29C66/7392 ,  B29C66/7394 ,  B29C66/8161 ,  B29C66/8322 ,  B29C66/843 ,  B29K2021/00 ,  B29K2021/003 ,  B29K2023/00 ,  B29K2101/12 ,  B29K2995/004 ,  B29L2031/753 ,  Y10T29/49826 ,  Y10T29/49828 ,  Y10T29/49829 ,  Y10T29/49966 ,  Y10T29/53435 ,  B29K2067/00 ,  B29K2055/02

摘要： A method for attaching a handle to a tablet to form a lollipop utilizes a specific work holder. The work holder has a tooling pallet with a plurality of openings going from a top surface to a bottom surface. A bullet and a spring are located in each opening and held in place by a plate that slides through a groove in the bottom surface of the tooling pallet to block the openings in the bottom surface. Each spring is positioned between a bullet and the plate. A tablet is placed in a cavity of each bullet and a handle is placed in contact with each tablet. High frequency mechanical vibrations, such as ultrasonic vibrations, are applied to a joint interface between each tablet and bullet until the joint interface reaches a molten state. The joint interfaces are then allowed to cool, thereby attaching a handle to each tablet and forming a lollipop.

摘要翻译： 用于将手柄附接到片剂以形成棒棒糖的方法利用特定的工件保持器。 工件支架具有工具托盘，其具有从顶表面到底表面的多个开口。 子弹和弹簧位于每个开口中，并通过滑块通过工具托盘的底表面中的凹槽滑动，从而阻挡底面中的开口。 每个弹簧位于子弹和板之间。 将片剂放置在每个子弹的空腔中，并且将手柄放置成与每个片剂接触。 高频机械振动，如超声振动，被施加到每个片剂和子弹之间的接合界面，直到接合界面达到熔融状态。 然后将接合界面冷却，从而将手柄附接到每个片剂并形成棒棒糖。

公开(公告)号：US20060280792A1

公开(公告)日：2006-12-14

申请号：US11446510

申请日：2006-06-05

申请人： Tahseen Chowdhury ,  Edward Gabrielski ,  Christopher Baker

发明人： Tahseen Chowdhury ,  Edward Gabrielski ,  Christopher Baker

IPC分类号： A61K9/20 ,  B29C65/00 ,  B29C65/08

CPC分类号： A61K9/2027 ,  A61J3/00 ,  A61J7/003 ,  A61K9/0056 ,  A61K9/2009 ,  A61K9/2013 ,  B29C65/645 ,  B29C66/71 ,  B29C66/7392 ,  B29C66/7394 ,  B29L2031/753 ,  B29K2025/08 ,  B29K2023/00 ,  B29K2021/003 ,  B29K2005/00 ,  B29K2003/00

摘要： The present invention relates to a method of attaching a handle to a solid oral dosage form by use of high frequency mechanical vibrations. The present invention also relates to a method of attaching a handle to a solid oral dosage form, the method comprising: (a) placing a handle in contact with a solid oral dosage form, wherein an area of contact between the handle and the solid oral dosage form forms a joint interface; (b) applying high frequency mechanical vibrations to the joint interface until the solid oral dosage form at the joint interface reaches a molten state; and (c) cooling the joint interface in a molten state to allow solidification, thereby attaching the handle to the solid oral dosage form.

摘要翻译： 本发明涉及通过使用高频机械振动将手柄附接到固体口服剂型的方法。 本发明还涉及一种将手柄附接到固体口服剂型的方法，所述方法包括：（a）将手柄放置成与固体口服剂型接触，其中手柄与固体口服之间的接触面积 剂型形成联合界面; （b）将高频机械振动施加到接合界面，直到接合界面处的固体口服剂型达到熔融状态; 和（c）在熔融状态下冷却接合界面以允许固化，从而将手柄附接到固体口服剂型。