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公开(公告)号：US08461539B2
公开(公告)日：2013-06-11
申请号：US12996471
申请日：2008-08-01
申请人： Taiga Yamaya , Hideo Murayama , Taku Inaniwa
发明人： Taiga Yamaya , Hideo Murayama , Taku Inaniwa
IPC分类号： G01T1/166
CPC分类号： G01T1/2985 , A61B6/037 , A61B6/583 , A61N5/1048 , A61N2005/1052 , A61N2005/1087
摘要： A combined radiation therapy/PET apparatus includes: an open PET device having multi-ring detector rings that are opposed to each other in the direction of the body axis so as to leave a gap therebetween; and a radiation therapy apparatus for performing radiation therapy through the gap. When imaging the condition of an affected area and a treatment beam for monitoring in radiation therapy of irradiating the affected area with X-rays, gamma rays, or particle beams, the apparatus covers a region of interest in the irradiation field of the radiation therapy with the field-of-view of the open PET device, thereby making possible the positioning of the irradiation field and treatment monitoring using PET images.
摘要翻译： 组合放射治疗/ PET装置包括：开放式PET装置，其具有多个环形探测器环，所述多环检测器环在体轴方向上彼此相对以在其间留有间隙; 以及用于通过间隙进行放射治疗的放射线治疗装置。 当对X射线，γ射线或粒子束照射受影响的区域进行辐射治疗的受影响区域状况和治疗束进行成像时，该装置覆盖放射治疗的照射场中的感兴趣区域， 开放的PET装置的视野，从而可以定位照射场和使用PET图像的处理监视。
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公开(公告)号：US08436312B2
公开(公告)日：2013-05-07
申请号：US12999041
申请日：2008-10-08
申请人： Naoko Inadama , Hideo Murayama , Kengo Shibuya , Fumihiko Nishikido , Taiga Yamaya , Eiji Yoshida
发明人： Naoko Inadama , Hideo Murayama , Kengo Shibuya , Fumihiko Nishikido , Taiga Yamaya , Eiji Yoshida
IPC分类号： G01T1/20
CPC分类号： G01T1/1644 , G01T1/2008
摘要： This aims to provide a DOI type radiation detector in which scintillation crystals arranged two-dimensionally on a light receiving surface to form rectangular section groups in extending directions of the light receiving surface of a light receiving element are stacked up to make a three-dimensional arrangement and responses of the crystals that have detected radiation are made possible to identify at response positions on the light receiving surface, so that a three-dimensional radiation detection position can be obtained. In the DOI type radiation detector, scintillation crystals are right triangle poles extending upwards from the light receiving surface and the response positions on the light receiving surface are characterized. With this structure, DOI identification of a plurality of layers can be carried out by simply performing an Anger calculation of a light receiving element signal.
摘要翻译： 其目的在于提供一种DOI型放射线检测器，其中，在光接收表面上二维布置的闪烁晶体在光接收元件的光接收表面的延伸方向上形成矩形截面组，以形成三维布置 并且能够检测到辐射的晶体的响应可以在光接收表面上的响应位置处识别，从而可以获得三维辐射检测位置。 在DOI型辐射检测器中，闪烁晶体是从光接收表面向上延伸的直角三角形磁极，并且在光接收表面上的响应位置被表征。 利用这种结构，可以通过简单地执行光接收元件信号的愤怒计算来执行多个层的DOI识别。
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公开(公告)号：US08222608B2
公开(公告)日：2012-07-17
申请号：US12936464
申请日：2008-04-14
申请人： Taiga Yamaya , Hideo Murayama
发明人： Taiga Yamaya , Hideo Murayama
IPC分类号： G01T1/166
CPC分类号： G01T1/2985 , A61B6/037 , A61B6/4258 , A61B6/4266 , A61B6/44 , A61B6/508
摘要： A PET scanner in which detector rings are arrayed in a multilayered manner so as to oppose each other in the body axis direction is provided. In the PET scanner, a predetermined number of detector units, each of which is made up of a predetermined number of detector rings, are arrayed so as to give each other a clearance, and a first ring set in which the clearance is less than or equal to a mean value of widths of two detector units forming each clearance and a second ring set constituted with a predetermined number of detector units are arrayed apart so as to give a clearance which is less than or equal to a mean value of the width of the first ring set and that of the second ring set, thereby imaging a field-of-view including the clearance and continuing in the body axis direction to an entire length of the first ring set and that of the second ring set.
摘要翻译： 提供了一种PET扫描仪，其中检测器环以多层方式排列成在体轴方向上彼此相对。 在PET扫描器中，排列有预定数量的检测器单元，每个检测器单元由预定数量的检测器环构成，以便彼此给予间隙;第一环组，其中间隙小于或等于 等于形成每个间隙的两个检测器单元的宽度的平均值，并且由预定数量的检测器单元构成的第二环组排列成分开，以便产生小于或等于宽度的平均值的间隙 所述第一环组和所述第二环组的第一环组和所述第二环组的整个长度成像为包括所述间隙的视场，并且在所述体轴方向上延伸到所述第一环组和所述第二环组的整个长度。
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公开(公告)号：US20110092814A1
公开(公告)日：2011-04-21
申请号：US12996471
申请日：2008-08-01
申请人： Taiga Yamaya , Hideo Murayama , Taku Inaniwa
发明人： Taiga Yamaya , Hideo Murayama , Taku Inaniwa
IPC分类号： A61B6/00
CPC分类号： G01T1/2985 , A61B6/037 , A61B6/583 , A61N5/1048 , A61N2005/1052 , A61N2005/1087
摘要： A combined radiation therapy/PET apparatus includes: an open PET device having multi-ring detector rings that are opposed to each other in the direction of the body axis so as to leave a gap therebetween; and a radiation therapy apparatus for performing radiation therapy through the gap. When imaging the condition of an affected area and a treatment beam for monitoring in radiation therapy of irradiating the affected area with X-rays, gamma rays, or particle beams, the apparatus covers a region of interest in the irradiation field of the radiation therapy with the field-of-view of the open PET device, thereby making possible the positioning of the irradiation field and treatment monitoring using PET images.
摘要翻译： 组合放射治疗/ PET装置包括：开放式PET装置，其具有多个环形探测器环，所述多环检测器环在体轴方向上彼此相对以在其间留有间隙; 以及用于通过间隙进行放射治疗的放射线治疗装置。 当对X射线，γ射线或粒子束照射受影响的区域进行辐射治疗的受影响区域状况和治疗束进行成像时，该装置覆盖放射治疗的照射场中的感兴趣区域， 开放的PET装置的视野，从而可以定位照射场和使用PET图像的处理监视。
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公开(公告)号：US20100128956A1
公开(公告)日：2010-05-27
申请号：US12450803
申请日：2007-04-17
申请人： Taiga Yamaya , Hideo Murayama , Shinichi Minohara
发明人： Taiga Yamaya , Hideo Murayama , Shinichi Minohara
CPC分类号： A61B6/03 , A61B6/037 , G01T1/1603 , G01T1/1611 , G01T1/1615 , G01T1/2985
摘要： A plurality of detector rings in which detectors arranged densely or spatially in a ring shape or in a polygonal shape are arranged, with an open space kept in the body axis direction, coincidences are measured for some of or all of detector pairs connecting the detector rings apart from the open space to perform three-dimensional image reconstruction, thereby imaging the open space between the detector rings as a tomographic image. Therefore, the open space is secured, with the deteriorated quality of an image suppressed, thus making it possible to easily gain access to a patient under PET scanning from outside a gantry and also provide irradiation of particle beams for cancer treatment as well as X-ray CT scanning.
摘要翻译： 多个检测器环布置有密集或空间上呈环形或多边形的检测器环，其开放空间保持在体轴方向上，对于连接检测器环的检测器对中的一些或全部测量出一致性 除了执行三维图像重建的开放空间之外，从而将检测器环之间的开放空间成像为断层图像。 因此，确保开放空间，抑制图像质量下降，从而能够容易地从台架外部在PET扫描下进入患者，并且还提供用于癌症治疗的粒子束的照射以及X- 射线CT扫描。
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6.发明授权Method for detecting radiation, device thereof, and positron emission tomography scanner 有权辐射检测方法及其装置及正电子发射断层扫描仪公开(公告)号：US09029789B2
公开(公告)日：2015-05-12
申请号：US12919358
申请日：2008-04-09
申请人： Kengo Shibuya , Taiga Yamaya , Naoko Inadama , Fumihiko Nishikido , Eiji Yoshida , Hideo Murayama
发明人： Kengo Shibuya , Taiga Yamaya , Naoko Inadama , Fumihiko Nishikido , Eiji Yoshida , Hideo Murayama
CPC分类号： G01T1/2985 , A61B6/037
摘要： A light receiver for detecting incident time is installed on the side of a radiation source of a scintillator (including a Cherenkov radiation emitter), and information (energy, incident time, an incident position, etc.) on radiation made incident into the scintillator is obtained by the output of the light receiver. It is, thereby, possible to identify an incident position and others of radiation into the scintillator at high accuracy.
摘要翻译： 用于检测入射时间的光接收器安装在闪烁体（包括切伦科夫辐射发射器）的辐射源的一侧，并且入射到闪烁体中的辐射的信息（能量，入射时间，入射位置等）是 通过光接收器的输出获得。 因此，可以以高精度将入射位置和其他辐射识别到闪烁体中。
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公开(公告)号：US09029787B2
公开(公告)日：2015-05-12
申请号：US13255769
申请日：2009-03-12
申请人： Taiga Yamaya , Hideo Murayama
发明人： Taiga Yamaya , Hideo Murayama
CPC分类号： G01T1/2985 , A61B6/037 , G01T1/1603
摘要： In an open PET device including a plurality of detector rings that are arranged apart in the direction of the body axis of a subject and having a physical open field of view area, at least one of the detector rings or another imaging device arranged in parallel is configured to be movable by simple device moving means in order to change the configuration of the PET device. This improves the versatility of the open PET device for easier introduction to facilities.
摘要翻译： 在包括多个检测器环的开放式PET装置中，所述多个检测器环被布置在被检体的体轴方向上并具有物理开放视野区域，检测器环或并行设置的另一成像装置中的至少一个是 被配置为通过简单的装置移动装置可移动，以便改变PET装置的构造。 这提高了开放式PET装置的多功能性，便于对设施的介绍。
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8.发明授权公开(公告)号：US08933410B2
公开(公告)日：2015-01-13
申请号：US13636936
申请日：2010-03-29
申请人： Naoko Inadama , Hideo Murayama , Taiga Yamaya , Mitsuo Watanabe , Takahiro Moriya , Kenshi Fukumitsu , Tomohide Omura
发明人： Naoko Inadama , Hideo Murayama , Taiga Yamaya , Mitsuo Watanabe , Takahiro Moriya , Kenshi Fukumitsu , Tomohide Omura
CPC分类号： G01T1/1644
摘要： A three-dimensional position-sensitive radiation detector is provided which has a three-dimensional array of photodetectors disposed on the surface of a scintillator block and which is capable of three-dimensionally identifying the position of light emission at which radiation has been detected within the detector. The three-dimensional position-sensitive radiation detector includes: a scintillator block including a central portion which restricts the direction of diffusion of light so as to direct the light in three axial directions and which has an optically discontinuous region, and an outer portion which is disposed on the outside of the central portion and which does not restrict the direction of diffusion of light; and photodetectors disposed on at least two outer circumferential surfaces of the scintillator block. The detector identifies three-dimensionally the position of light emission, thereby preventing deterioration in position discrimination performance even when inner scintillator elements are smaller than the photodetectors.
摘要翻译： 提供了三维位置敏感的放射线检测器，其具有设置在闪烁体块的表面上的光电检测器的三维阵列，并且能够三维地识别已经在其内检测到辐射的发光的位置 探测器。 三维位置敏感型放射线检测器包括：闪烁体块，其包括限制光的扩散方向的中心部，以使光在三个轴向引导，并具有光学不连续区域;外部部分 设置在中心部分的外侧，并且不限制光的扩散方向; 以及设置在闪烁体块的至少两个外周表面上的光电检测器。 检测器三维地识别发光的位置，从而即使当内部闪烁体元件小于光电检测器时也防止位置判别性能的劣化。
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公开(公告)号：US08594404B2
公开(公告)日：2013-11-26
申请号：US12450803
申请日：2007-04-17
申请人： Taiga Yamaya , Hideo Murayama , Shinichi Minohara
发明人： Taiga Yamaya , Hideo Murayama , Shinichi Minohara
IPC分类号： A61B6/03
CPC分类号： A61B6/03 , A61B6/037 , G01T1/1603 , G01T1/1611 , G01T1/1615 , G01T1/2985
摘要： A plurality of detector rings in which detectors arranged densely or spatially in a ring shape or in a polygonal shape are arranged, with an open space kept in the body axis direction, coincidences are measured for some of or all of detector pairs connecting the detector rings apart from the open space to perform three-dimensional image reconstruction, thereby imaging the open space between the detector rings as a tomographic image. Therefore, the open space is secured, with the deteriorated quality of an image suppressed, thus making it possible to easily gain access to a patient under PET scanning from outside a gantry and also provide irradiation of particle beams for cancer treatment as well as X-ray CT scanning.
摘要翻译： 多个检测器环布置有密集或空间上呈环形或多边形的检测器环，其开放空间保持在体轴方向上，对于连接检测器环的检测器对中的一些或全部测量出一致性 除了执行三维图像重建的开放空间之外，从而将检测器环之间的开放空间成像为断层图像。 因此，确保开放空间，抑制图像质量下降，从而能够容易地从台架外部在PET扫描下进入患者，并且还提供用于癌症治疗的粒子束的照射以及X- 射线CT扫描。
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公开(公告)号：US07671339B2
公开(公告)日：2010-03-02
申请号：US11658699
申请日：2006-12-25
申请人： Kengo Shibuya , Tomoaki Tsuda , Fumihiko Nishikido , Naoko Inadama , Eiji Yoshida , Taiga Yamaya , Hideo Murayama
发明人： Kengo Shibuya , Tomoaki Tsuda , Fumihiko Nishikido , Naoko Inadama , Eiji Yoshida , Taiga Yamaya , Hideo Murayama
CPC分类号： G01T1/2985 , A61B6/037
摘要： A positron emission tomography (PET) scanner is provided which uses information on the time-of-flight difference (TOF) between annihilation radiations for image reconstruction. The scanner has detection time correction information (memory) corresponding to information on coordinates in a radiation detection element (e.g., scintillator crystal), in the depth and lateral directions, at which an interaction has occurred between an annihilation radiation and the crystal. Reference is made to the detection time correction information, thereby providing information on time-of-flight difference with improved accuracy. As such, an improved signal to noise ratio and spatial resolution are provided for image reconstruction using time-of-flight (TOF) difference.
摘要翻译： 提供了一种正电子发射断层扫描仪（PET）扫描仪，其使用关于图像重建的湮灭辐射之间的飞行时间差（TOF）的信息。 扫描仪具有与在湮灭辐射与晶体之间发生相互作用的深度和横向上的放射线检测元件（例如，闪烁体晶体）中的坐标信息相对应的检测时间校正信息（存储器）。 参考检测时间校正信息，从而提供关于飞行时间差异的信息，提高精度。 因此，为使用飞行时间（TOF）差异的图像重建提供了改善的信噪比和空间分辨率。
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