公开(公告)号：US4784856A

公开(公告)日：1988-11-15

申请号：US83886

申请日：1987-08-10

申请人： Mutsumi Fukuda ,  Takashi Nakagawa ,  Takaji Kishi ,  Michiharu Ando ,  Masahachi Yoshioka

发明人： Mutsumi Fukuda ,  Takashi Nakagawa ,  Takaji Kishi ,  Michiharu Ando ,  Masahachi Yoshioka

IPC分类号： A61K9/70 ,  A61L15/58 ,  A61F13/02 ,  A61F13/00 ,  A61K31/79 ,  A61L15/06

CPC分类号： A61K9/7053 ,  A61K9/7061 ,  A61L15/58

摘要： A percutaneous administration type pharmaceutical preparation in tape form comprising a flexible backing, which is not permeable by the active ingredient, and an adhesive base layer formed on said flexible backing; said adhesive base layer consisting essentially of an adhesive base material and an active ingredient compatible with said adhesive base material, wherein said adhesive base material is a copolymer containing 2-ethylhexyl acrylate (EHA) in a concentration of 45 mole% or more and N-vinyl-2-pyrrolidone (VP) in a concentration of 20 to 55 mole%, and said active ingredient is isosorbide dinitrate (ISDN) which is contained in a concentration of 10% by weight or more in said adhesive base material.

摘要翻译： 一种胶带形式的经皮给药型药物制剂，其包含不能被活性成分渗透的柔性背衬和形成在所述柔性背衬上的粘合剂基层; 所述粘合剂基层基本上由粘合剂基材和与所述粘合剂基材相容的活性成分组成，其中所述粘合剂基材是含有浓度为45摩尔％以上的丙烯酸2-乙基己酯（EHA）和N- 浓度为20〜55摩尔％的乙烯基-2-吡咯烷酮（VP），所述活性成分为所述粘合剂基材中浓度为10重量％以上的硝酸异山梨酯（ISDN）。

公开(公告)号：US4495243A

公开(公告)日：1985-01-22

申请号：US180010

申请日：1980-08-21

申请人： Takaji Kishi

发明人： Takaji Kishi

IPC分类号： C09K3/00 ,  C08F20/00 ,  C08F20/34 ,  C08F20/36 ,  C08F290/00 ,  C08F299/00 ,  C08L33/14 ,  C09D133/14 ,  C09J7/02

CPC分类号： C09J7/0228 ,  C09D133/14 ,  C09J7/025 ,  C08L2205/02 ,  C08L33/14 ,  C09J2400/283 ,  C09J2423/005 ,  C09J2433/005 ,  C09J2451/005 ,  C09J2475/005 ,  Y10T428/2839 ,  Y10T428/2848 ,  Y10T428/31565 ,  Y10T428/31591

摘要： A release agent comprising (A) a polymer of at least one vinyl monomer of the general formulaCH.sub.2 .dbd.CR.sub.1 COO(CH.sub.2 CHR.sub.2 O).sub.n CONHR (I)wherein R.sub.1 and R.sub.2, independently from each other, represent hydrogen or a methyl group, R represents an alkyl group having at least 12 carbon atoms or a fluoroalkyl group having at least 6 carbon atoms, and n is an integer of from 1 to 6,(B) a copolymer of at least one vinyl monomer of general formula (I) above and another compound copolymerizable therewith, or a mixture of said polymer (A) and said copolymer (B); and a product prepared by coating the said release agent on a non-adhesive surface of an adhesive article having an adhesive surface and the non-adhesive surface or on the surface of a release paper.

摘要翻译： 一种脱模剂，其包含（A）至少一种通式CH 2 = CR 1 COO（CH 2 CHR 2 O）n CONHR（I）的乙烯基单体的聚合物，其中R 1和R 2彼此独立地表示氢或甲基，R表示烷基 具有至少12个碳原子的基团或具有至少6个碳原子的氟代烷基，n是1至6的整数，（B）至少一种上述通式（I）的乙烯基单体与另一种化合物 可与其共聚，或所述聚合物（A）和所述共聚物（B）的混合物; 以及通过将所述脱模剂涂布在具有粘合剂表面和非粘合表面或剥离纸表面的粘合剂制品的非粘性表面上而制备的产品。