公开(公告)号：US20030189001A1

公开(公告)日：2003-10-09

申请号：US10119132

申请日：2002-04-08

申请人： Takao Tsuda; Chemco Scientific Co., Ltd. ,  Motonori Munesue

发明人： Takao Tsuda ,  Shinya Kitagawa ,  Motonori Munesue

IPC分类号： B01D015/08

CPC分类号： B01J20/286 ,  B01J20/28054 ,  B01J20/28097 ,  B01J20/282 ,  B01J2220/54 ,  B01J2220/84 ,  G01N30/52 ,  G01N30/6078 ,  G01N2030/525 ,  G01N2030/567

摘要： In an open capillary column, a stationary phase is formed on the inner wall of a capillary tube. This stationary phase comprises a number of pores on the surface of the capillary tube, and each of pore has an expanded hollow in the stationary phase. A manufacturing method of an open capillary column comprises the steps of giving alkaline treatment to an inner wall of an open capillary tube, applying one of oligo silica, oligo zirconia and oligo titania on the inner wall, filling the open capillary tube with alkaline solution to form one of a silica layer, a zirconia layer and titania layer, discharging the alkaline solution and heat-treating the capillary tube to form a base of a stationary phase. The open capillary column of the present invention comprises a stationary phase having a very large surface area. It is useful for a separation analysis field such as liquid chromatography and electrochromatography.

摘要翻译： 在开放的毛细管柱中，在毛细管的内壁上形成固定相。 该固定相包括毛细管表面上的多个孔，并且每个孔在固定相中具有膨胀的中空。 开放毛细管柱的制造方法包括以下步骤：对开放毛细管的内壁进行碱处理，在内壁上施加低氧二氧化硅，低氧二氧化锆和低氧二氧化钛之一，用碱性溶液填充开放的毛细管， 形成二氧化硅层，氧化锆层和二氧化钛层之一，排出碱溶液并热处理毛细管以形成固定相的碱。 本发明的开放毛细管柱包括具有非常大的表面积的固定相。 它对于分离分析领域如液相色谱和电色谱是有用的。