公开(公告)号：US11559605B2

公开(公告)日：2023-01-24

申请号：US16313254

申请日：2017-06-08

申请人： Takashi YOKOO ,  BIOS Co.. Ltd

发明人： Takashi Yokoo ,  Shuichiro Yamanaka

IPC分类号： A61L27/36 ,  A61P13/12 ,  A01K67/027 ,  A61K35/22 ,  A61L27/38 ,  C12N5/071

摘要： The present invention provides a kidney production method including a step of tissue-specifically removing a metanephric mesenchyme of a metanephros of a non-human animal; a step of transplanting, into the metanephros, a kidney precursor cell derived from a non-human animal which is allogeneic or xenogeneic to the non-human animal; and a step of advancing development of the metanephros, which is a step in which the transplanted kidney precursor cell is differentiated and matured to form a part of the kidney.

公开(公告)号：US11607425B2

公开(公告)日：2023-03-21

申请号：US16313253

申请日：2017-06-08

申请人： Takashi Yokoo ,  BIOS Co., Ltd

发明人： Takashi Yokoo ,  Shuichiro Yamanaka

IPC分类号： A61L27/36 ,  A61K35/22 ,  A61P13/12 ,  C12N5/071 ,  A01K67/027 ,  A61L27/38 ,  C12N15/09

摘要： The present invention provides a kidney production method including a step of tissue-specifically removing a metanephric mesenchyme of a metanephros of a non-human animal; a step of transplanting a human kidney precursor cell into the metanephros; and a step of advancing development of the metanephros, which is a step in which the transplanted human kidney precursor cell is differentiated and matured to form a part of the kidney.