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    OXADIAZOLE DERIVATIVE HAVING ENDOTHELIAL LIPASE INHIBITORY ACTIVITY
    4.
    发明申请
    OXADIAZOLE DERIVATIVE HAVING ENDOTHELIAL LIPASE INHIBITORY ACTIVITY 有权
    具有内皮脂肪酶抑制活性的氧化氮衍生物

    公开(公告)号：US20120253040A1

    公开(公告)日：2012-10-04

    申请号：US13516441

    申请日：2010-12-14

    申请人： Koji Masuda ,  Shiro Kida ,  Naoki Yoshikawa ,  Manabu Katou ,  Terukazu Kato ,  Mado Nakajima ,  Eiichi Kojima ,  Mitsuhiro Yonehara

    发明人： Koji Masuda ,  Shiro Kida ,  Naoki Yoshikawa ,  Manabu Katou ,  Terukazu Kato ,  Mado Nakajima ,  Eiichi Kojima ,  Mitsuhiro Yonehara

    IPC分类号： C07D271/10 ,  C07D413/10 ,  C07D241/36 ,  C07D513/04 ,  C07D417/12 ,  C07D215/14 ,  C07D285/135

    CPC分类号： A61K31/423 ,  A61K31/4245 ,  A61K31/428 ,  A61K31/433 ,  A61K31/437 ,  A61K31/4439 ,  A61K31/454 ,  A61K31/5377 ,  C07D413/06 ,  C07D417/06 ,  C07D417/14 ,  C07D513/04

    摘要： Disclosed is a compound which is useful as an endothelial lipase inhibitor.A compound represented by the formula: its pharmaceutically acceptable salt, or a solvate thereof, wherein Ring A is aromatic carbocycle or aromatic heterocycle, Z is —NR5—, —O— or —S—, R5 is hydrogen, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, substituted or unsubstituted aryl or the like, R1 is hydrogen, halogen, hydroxy, cyano, nitro, carboxy, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl or the like, R2 and R3 are each independently hydrogen, halogen, hydroxy or the like, R4 is a group represented by the formula: —(CR6R7)n-R8, wherein R6 and R7 are each independently hydrogen, halogen, hydroxy or the like, n is an integer of 0 to 3, R8 is carboxy, cyano, substituted or unsubstituted alkyl or the like, Rx is halogen, hydroxy, cyano, nitro, carboxy, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl or the like, m is an integer of 0 to 3.

    摘要翻译： 公开了可用作内皮脂肪酶抑制剂的化合物。 由下式表示的化合物：其药学上可接受的盐或其溶剂化物，其中环A是芳族碳环或芳族杂环，Z是-NR5-，-O-或-S-，R5是氢，取代或未取代的烷基， 取代或未取代的烯基，取代或未取代的炔基，取代或未取代的芳基等，R 1是氢，卤素，羟基，氰基，硝基，羧基，取代或未取代的烷基，取代或未取代的烯基等， 独立地是氢，卤素，羟基等，R 4是由下式表示的基团： - （CR 6 R 7）n -R 8，其中R 6和R 7各自独立地为氢，卤素，羟基等，n为0〜 3，R8为羧基，氰基，取代或未取代的烷基等，Rx为卤素，羟基，氰基，硝基，羧基，取代或未取代的烷基，取代或未取代的烯基等，m为0〜3的整数。

    Sulfonamide derivative having isoxazole ring
    5.
    发明授权
    Sulfonamide derivative having isoxazole ring 失效
    具有异恶唑环的磺酰胺衍生物

    公开(公告)号：US07825146B2

    公开(公告)日：2010-11-02

    申请号：US10565948

    申请日：2004-07-28

    申请人： Fumihiko Watanabe ,  Naoki Yoshikawa ,  Yoshinori Tamura

    发明人： Fumihiko Watanabe ,  Naoki Yoshikawa ,  Yoshinori Tamura

    IPC分类号： A61K31/422

    CPC分类号： C07D261/08 ,  A61K31/42

    摘要： A compound represented by the general formula (I-A): wherein R1 is hydroxy and the like; R2 is optionally substituted lower alkyl and the like; R3 is hydrogen atom and the like; R4 is optionally substituted arylene and the like; R5 is a group represented by the formula: R6 is optionally substituted aryl and the like, its optically active substance, their pharmaceutically acceptable salt, or a solvate thereof; and a metalloproteinase inhibitor containing them.

    摘要翻译： 由通式（I-A）表示的化合物：其中R1是羟基等; R2是任选取代的低级烷基等; R3是氢原子等; R4是任选取代的亚芳基等; R5是由下式表示的基团：R6是任选取代的芳基等，其光学活性物质，其药学上可接受的盐或其溶剂化物; 和含有它们的金属蛋白酶抑制剂。

    VEHICLE SWITCH
    6.
    发明申请
    VEHICLE SWITCH 有权
    车辆开关

    公开(公告)号：US20090128140A1

    公开(公告)日：2009-05-21

    申请号：US12272884

    申请日：2008-11-18

    申请人： Hisashi Nishikawa ,  Naoki Yoshikawa

    发明人： Hisashi Nishikawa ,  Naoki Yoshikawa

    IPC分类号： G01R33/00

    CPC分类号： G01R33/09

    摘要： A holder is disposed in the case. The holder is mounted with an actuator that moves in the predetermined direction and a wiring board having a detector. A positioning mechanism between relevant components for detecting the positions of components is provided such as a wiring board and a holder, the position of magnet in particular. In this way, the magnet and the detector opposing to each other are positioned. As a result, when a vehicle switch is assembled, the variation in position of the magnet and detector is reduced. Accordingly, the vehicle switch is enhanced in switching accuracy and becomes capable of reliable operation.

    摘要翻译： 把持器放置在壳体中。 保持器安装有沿预定方向移动的致动器和具有检测器的布线板。 提供了用于检测部件位置的相关部件之间的定位机构，例如布线板和保持器，特别是磁体的位置。 以这种方式，磁体和彼此相对的检测器被定位。 结果，当车辆开关组装时，磁体和检测器的位置变化减小。 因此，车辆开关的开关精度提高，能够可靠地运转。

    SWITCH AND SWITCH DEVICE USING SAME
    7.
    发明申请
    SWITCH AND SWITCH DEVICE USING SAME 有权
    使用相同的开关和开关装置

    公开(公告)号：US20090121816A1

    公开(公告)日：2009-05-14

    申请号：US12266689

    申请日：2008-11-07

    申请人： Hisashi Nishikawa ,  Naoki Yoshikawa

    发明人： Hisashi Nishikawa ,  Naoki Yoshikawa

    IPC分类号： H01H9/00

    CPC分类号： H01H47/002 ,  H01H13/52 ,  H01H36/0006 ,  H01H36/0033 ,  H01H36/0046

    摘要： Regarding a switch used for various controls of a motor vehicle in particular and a switch device using the switch, it becomes possible to simplify the configuration and to perform reliable detection of trouble. A first detector is disposed on a surface opposing to a magnet fitted to an actuator, and a second detector is disposed thereunder. A controller detects magnetism of the magnet by using the first detector and the second detector. In case one of the detectors is out of order, it can also be detected from ON/OFF signal from the first detector and the second detector.

    摘要翻译： 关于用于特别是机动车辆的各种控制的开关以及使用该开关的开关装置，能够简化构成并进行可靠的故障检测。 第一检测器设置在与装配到致动器的磁体相对的表面上，并且第二检测器设置在其下方。 控制器通过使用第一检测器和第二检测器来检测磁体的磁性。 在一个检测器故障的情况下，也可以从第一检测器和第二检测器的ON / OFF信号检测。

    Switch and switch device using same
    8.
    发明授权
    Switch and switch device using same 有权
    开关和开关器件使用相同

    公开(公告)号：US08154367B2

    公开(公告)日：2012-04-10

    申请号：US12266689

    申请日：2008-11-07

    申请人： Hisashi Nishikawa ,  Naoki Yoshikawa

    发明人： Hisashi Nishikawa ,  Naoki Yoshikawa

    IPC分类号： H01H9/00

    CPC分类号： H01H47/002 ,  H01H13/52 ,  H01H36/0006 ,  H01H36/0033 ,  H01H36/0046

    摘要： Regarding a switch used for various controls of a motor vehicle in particular and a switch device using the switch, it becomes possible to simplify the configuration and to perform reliable detection of trouble. A first detector is disposed on a surface opposing to a magnet fitted to an actuator, and a second detector is disposed thereunder. A controller detects magnetism of the magnet by using the first detector and the second detector. In case one of the detectors is out of order, it can also be detected from ON/OFF signal from the first detector and the second detector.

    摘要翻译： 关于用于特别是机动车辆的各种控制的开关以及使用该开关的开关装置，能够简化构成并进行可靠的故障检测。 第一检测器设置在与装配到致动器的磁体相对的表面上，并且第二检测器设置在其下方。 控制器通过使用第一检测器和第二检测器来检测磁体的磁性。 在一个检测器故障的情况下，也可以从第一检测器和第二检测器的ON / OFF信号检测。

    COLLECTION METHOD, COLLECTION SYSTEM, RECYCLING METHOD AND COLLECTION CONTAINER FOR USED PRINTING PLATE
    10.
    发明申请
    COLLECTION METHOD, COLLECTION SYSTEM, RECYCLING METHOD AND COLLECTION CONTAINER FOR USED PRINTING PLATE 审中-公开
    收集方法，收集系统，回收方法和用于印刷板的收集容器

    公开(公告)号：US20090089077A1

    公开(公告)日：2009-04-02

    申请号：US12239801

    申请日：2008-09-28

    申请人： Naoki Yoshikawa ,  Yoshio Okishi ,  Masakazu Osada

    发明人： Naoki Yoshikawa ,  Yoshio Okishi ,  Masakazu Osada

    IPC分类号： G06Q10/00 ,  G06F17/00 ,  G06Q50/00 ,  G06K9/00

    CPC分类号： G06Q10/08 ,  C22B7/005 ,  C22B21/0069 ,  G06Q10/30 ,  Y02P10/212 ,  Y02W90/20

    摘要： An IC tag is fixed to a printing plate. An ID code is stored in the IC tag. A used printing plate is collected using a collection container. The collection container is provided with a reception device of the collected used printing plates. The reception device is provided with an IC tag reader. An ID code of the used printing plate is read with the IC tag reader. According to the read ID code, whether to reuse the used printing plate for a substrate of the printing plate is judged. The used printing plates judged to be reused are sent to an aluminum substrate recycling plant and recycled as raw materials for aluminum used in production of the substrates for the printing plates.

    摘要翻译： IC标签固定在印版上。 ID代码存储在IC标签中。 使用收集容器收集用过的印版。 收集容器设置有收集的废印版的接收装置。 接收装置设置有IC标签读取器。 使用IC标签读取器读取所使用的印版的ID码。 根据读取的ID码，判断是否重新使用用于印版的基板的废印版。 判断为重复使用的废印版被送到铝基板回收厂，并作为生产用于印版的基板的铝的原料进行回收。