公开(公告)号：US20050197675A1

公开(公告)日：2005-09-08

申请号：US11062324

申请日：2005-02-18

申请人： Tamir David ,  Shai Ayal ,  Omry Ezra ,  Ehud Cohen

发明人： Tamir David ,  Shai Ayal ,  Omry Ezra ,  Ehud Cohen

IPC分类号： A61N20060101 ,  A61N1/05 ,  A61N1/18 ,  A61N1/36 ,  A61N1/362 ,  A61N1/365

CPC分类号： A61B5/412 ,  A61B5/024 ,  A61B5/4029 ,  A61B5/4041 ,  A61B5/7217 ,  A61N1/0551 ,  A61N1/0556 ,  A61N1/36114 ,  A61N1/3621 ,  A61N1/3627

摘要： Apparatus is provided including an electrode device, adapted to be coupled to a site of a subject; and a control unit, adapted to drive the electrode device to apply a current to the site intermittently during alternating “on” and “off”periods, each of the “on” periods having an “on” duration equal to between 1 and 10 seconds, and each of the “off” periods having an “off”duration equal to at least 50% of the “on” duration. Other embodiments are also described.

摘要翻译： 提供了包括电极装置的装置，其适于联接到受试者的部位; 以及控制单元，其适于在交替的“接通”和“关闭”周期期间驱动电极装置间歇地施加电流到场地，每个“接通”周期具有等于1至10秒的“接通”持续时间 ，并且每个“关闭”周期具有等于“开启”持续时间的至少50％的“关闭”持续时间。 还描述了其它实施例。

公开(公告)号：US20050267542A1

公开(公告)日：2005-12-01

申请号：US11064446

申请日：2005-02-22

申请人： Tamir David ,  Shai Ayal ,  Omry Ezra ,  Ehud Cohen

发明人： Tamir David ,  Shai Ayal ,  Omry Ezra ,  Ehud Cohen

IPC分类号： A61N1/36 ,  A61N1/362 ,  A61N1/365

CPC分类号： A61B5/412 ,  A61B5/024 ,  A61B5/4029 ,  A61B5/4041 ,  A61B5/7217 ,  A61N1/0551 ,  A61N1/0556 ,  A61N1/36114 ,  A61N1/3621 ,  A61N1/3622 ,  A61N1/3627

摘要： Apparatus is provided including an implantable sensor, adapted to sense an electrical parameter of a heart of a subject, and a first control unit, adapted to apply pulses to the heart responsively to the sensed parameter, the pulses selected from the list consisting of: pacing pulses and anti-arrhythmic energy. The apparatus further includes an electrode device, adapted to be coupled to a site of the subject selected from the list consisting of: a vagus nerve of the subject, an epicardial fat pad of the subject, a pulmonary vein of the subject, a carotid artery of the subject, a carotid sinus of the subject, a coronary sinus of the subject, a vena cava vein of the subject, a right ventricle of the subject, and a jugular vein of the subject; and a second control unit, adapted to drive the electrode device to apply to the site a current that increases parasympathetic tone of the subject and affects a heart rate of the subject. The first and second control units are not under common control. At least one of the control units is adapted to coordinate an aspect of its operation with an aspect of operation of the other control unit. Other embodiments are also described.

摘要翻译： 提供了包括适于感测对象的心脏的电参数的可植入传感器和适于响应于所感测的参数向心脏施加脉冲的第一控制单元，从列表中选择的脉冲包括：起搏 脉冲和抗心律变能。 所述装置还包括电极装置，适于耦合到选自以下列表的对象的部位：包括受试者的迷走神经，受试者的心外膜脂肪垫，受试者的肺静脉，颈动脉 受试者的颈动脉窦，受试者的冠状窦，受试者的腔静脉，受试者的右心室和受试者的颈静脉; 以及第二控制单元，其适于驱动所述电极装置向所述部位施加增加所述受试者的副交感神经紧张并影响所述受试者的心率的电流。 第一和第二控制单元不在一般控制之下。 控制单元中的至少一个适于将其操作的一个方面与其他控制单元的操作的一个方面协调。 还描述了其它实施例。