公开(公告)号：US12050448B2

公开(公告)日：2024-07-30

申请号：US17586995

申请日：2022-01-28

申请人： Tata Consultancy Services Limited

发明人： Venkata Sudheendra Buddhiraju ,  Venkataramana Runkana ,  Vishnu Swaroopji Masampally ,  Anshul Agarwal ,  Amey Ahsok Kulkarni ,  Keshari Nandan Gupta ,  Navnath Manohar Deore ,  Vinesh Balakrishnan Yezhuvath ,  Anamika Tiwari ,  Anurag Singh Rathore ,  Garima Thakur ,  Nikita Saxena ,  Shantanu Banerjee

IPC分类号： G05B19/05 ,  C12M1/36 ,  G05B13/04 ,  G06N5/01

CPC分类号： G05B19/054 ,  G05B19/056 ,  G06N5/01 ,  G05B2219/13149 ,  G05B2219/14058 ,  G05B2219/14083

摘要： Process control of continuous production of biomolecules is a major challenge due to complex nature of processes and time scales of operations involved. Availability of key process variables in real-time is one of main requirements. This disclosure relates to a processor implemented method of controlling a continuous bioprocessing plant which includes at least one of: receiving, an input data associated with one or more equipments; generating, by a recipe builder, a sequence of unit operations to determine at least one job order based on the at least input data; obtaining, a control decision associated with a control parameter based on the at least one job order; communicating, via the middleware, the control decision associated with the control parameter to the PLC; and executing, by a control system of the PLC, the control decision on a unit equipment to control: (i) a continuous bioprocessing train, and (ii) an individual unit operation.