公开(公告)号：US20240352484A1

公开(公告)日：2024-10-24

申请号：US18638775

申请日：2024-04-18

申请人： Technion Research & Development Foundation Limited ,  Rambam Med-Tech Ltd.

发明人： Asya ROLLS ,  Lior GEPSTEIN ,  Hedva HAYKIN ,  Hilla AZULAY-DEBBY

IPC分类号： C12N15/86 ,  A61B5/055

CPC分类号： C12N15/86 ,  A61B5/055 ,  C12N2750/14143

摘要： Provided is reward system activation for therapeutic purposes. Accordingly there is provided a method of treating a disease in a subject in need thereof, the method comprising subjecting the subject to a treatment module which activates the reward system of the subject.

公开(公告)号：US20230338741A1

公开(公告)日：2023-10-26

申请号：US18214664

申请日：2023-06-27

申请人： TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED

发明人： Asya ROLLS ,  Tamar KOREN ,  Hilla AZULAY-DEBBY ,  Tamar BEN SHAANAN

IPC分类号： A61N2/00 ,  A61N1/36 ,  A61N5/06 ,  A61N7/00

CPC分类号： A61N2/006 ,  A61N1/36014 ,  A61N5/0622 ,  A61N7/00 ,  A61N2007/0026

摘要： The present invention is directed to a method for treating a bowel disease in a subject in need thereof, the method comprising inhibiting the activity of neurons of the insular cortex of the subject. Further provided is a system comprising a transcranial stimulation transducing coil for transcranial stimulation configured to provide a series of pulses to neurons of the insular cortex.

公开(公告)号：US20210046324A1

公开(公告)日：2021-02-18

申请号：US16768974

申请日：2018-12-06

申请人： TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED

发明人： Asya ROLLS ,  Tamar KOREN ,  Hilla AZULAY-DEBBY ,  Tamar BEN SHAANAN

IPC分类号： A61N2/00 ,  A61N7/00 ,  A61N1/36 ,  A61N5/06

摘要： The present invention is directed to a method for treating a bowel disease in a subject in need thereof, the method comprising inhibiting the activity of neurons of the insular cortex of the subject. Further provided is a system comprising a transcranial stimulation transducing coil for transcranial stimulation configured to provide a series of pulses to neurons of the insular cortex.

公开(公告)号：US20200376287A1

公开(公告)日：2020-12-03

申请号：US16885696

申请日：2020-05-28

申请人： TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED

发明人： Asya ROLLS ,  Maria KROT ,  Hilla AZULAY-DEBBY

IPC分类号： A61N2/00 ,  C07K14/495

摘要： The present invention, in some embodiments thereof, is directed to a method for preserving or promoting oral tolerance in a subject in need thereof, including modulating neurons in the mid-posterior region of the insular cortex (mpIC). Further provided is a method for increasing TGF-β signaling in a subject in need thereof.