公开(公告)号：US09655848B2

公开(公告)日：2017-05-23

申请号：US14440834

申请日：2013-11-19

Applicant: Technion Research and Development Foundation Limited

Inventor： Nahum Allon ,  Moshe Gavish

IPC: A61K9/127 ,  A61K47/42 ,  A61K31/365 ,  C07K1/107 ,  C07K7/00 ,  C12N15/88

CPC classification number: A61K9/1272 ,  A61K9/1277 ,  A61K31/365 ,  A61K47/42 ,  C07K1/1077 ,  C07K7/00 ,  C12N15/88 ,  C12N2320/32 ,  C12N2320/53 ,  C12N2500/36 ,  C12Q2563/161

Abstract: The present invention provides a liposome based composition wherein the liposome includes a peptide conjugated thereto via a peptide bond, wherein the peptide includes a spacer amino acid and a short Apolipoprotein E recognition sequence or a short Amyloid beta recognition sequence. This invention further provides a process for making the liposome and methods of utilizing the liposome based composition for therapeutic and diagnostic purposes.