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公开(公告)号：US20240197681A1
公开(公告)日：2024-06-20
申请号：US18553170
申请日：2022-04-01
发明人： Sam CLARK , Scott THOMPSON
IPC分类号： A61K31/4045 , A61K9/20 , A61K31/137 , A61K31/44 , A61K31/522 , A61K31/675 , A61K39/00 , A61K45/06 , A61P25/24
CPC分类号： A61K31/4045 , A61K9/20 , A61K31/137 , A61K31/44 , A61K31/522 , A61K31/675 , A61K45/06 , A61P25/24 , A61K2039/545
摘要： Provided herein are compositions relating to psychedelics and serotonin receptor modulators. Further provided herein are methods of treating a disease or disorder (e.g., depression or diseases or disorders related to depression) comprising administering psychedelics and serotonin receptor modulators.
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2.发明公开公开(公告)号：US20240000795A1
公开(公告)日：2024-01-04
申请号：US17945865
申请日：2022-09-15
发明人： Sam CLARK
IPC分类号： A61K31/5513 , A61K31/519 , A61K31/554 , A61K45/06 , A61P25/14
CPC分类号： A61K31/5513 , A61K31/519 , A61K31/554 , A61K45/06 , A61P25/14
摘要： Provided herein are compositions relating to psychedelics and serotonin receptor modulators. Further provided herein are methods of suppressing or halting hallucinogenic effects of a psychedelic and methods of treating a disease or disorder (e.g., depression or diseases or disorders related to depression) comprising administering psychedelics and serotonin receptor modulators.
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公开(公告)号：US20230212119A1
公开(公告)日：2023-07-06
申请号：US18173717
申请日：2023-02-23
IPC分类号： C07D209/32 , C07D209/14 , C07D209/12
CPC分类号： C07D209/32 , C07D209/14 , C07D209/12
摘要： Described herein are compounds that are derivatives of DMT or 5-MeO-DMT and can be metabolically converted to N,N-dimethyltryptamine or analogs thereof upon administration to a subject. In certain embodiments, the compounds described herein are useful for the treatment of conditions associated with a neurological disease.
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公开(公告)号：US20240317724A1
公开(公告)日：2024-09-26
申请号：US18576719
申请日：2022-07-07
IPC分类号： C07D405/14 , A61K31/36 , A61K31/4525 , A61K31/4545 , C07D317/58 , C07D405/12 , C07D407/12
CPC分类号： C07D405/14 , A61K31/36 , A61K31/4525 , A61K31/4545 , C07D317/58 , C07D405/12 , C07D407/12
摘要： Described herein are compounds that are derivatives (e.g., prodrugs) of 3,4-Methylenedioxymethamphetamine (MDMA). Also described herein are uses of the compounds provided herein for treating or preventing a disease, disorder, or condition in which an increased level of MDMA is beneficial.
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5.发明公开公开(公告)号：US20240294460A1
公开(公告)日：2024-09-05
申请号：US18685002
申请日：2022-08-19
IPC分类号： C07C217/60 , A61K31/137
CPC分类号： C07C217/60 , A61K31/137 , C07B2200/05
摘要： Provided herein are deuterated analogs of 4-bromo-2,5-dimethoxyphenethylamine (2C-B) and related compounds and their uses for the treatment of conditions associated with a neurological disease.
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公开(公告)号：US20240116870A1
公开(公告)日：2024-04-11
申请号：US18484211
申请日：2023-10-10
IPC分类号： C07D209/32 , C07D209/12 , C07D209/14
CPC分类号： C07D209/32 , C07D209/12 , C07D209/14
摘要： Described herein are compounds that are derivatives of DMT or 5-MeO-DMT and can be metabolically converted to N,N-dimethyltryptamine or analogs thereof upon administration to a subject. In certain embodiments, the compounds described herein are useful for the treatment of conditions associated with a neurological disease.
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