Method for the purification of a bifidobacteria-proliferating substance
    4.
    发明授权
    Method for the purification of a bifidobacteria-proliferating substance 失效
    净化双歧杆菌增殖物质的方法

    公开(公告)号:US5152897A

    公开(公告)日:1992-10-06

    申请号:US753310

    申请日:1991-08-30

    摘要: A method for the purification of a bifidobacteria-proliferating substance is provided which comprises adjusting the temperature of soybean whey to 50.degree. to 100.degree. C. and the pH thereof to 6.5 to 10 either by adding an alkaline substance to the whey and heating it or by heating the whey and adding the alkaline substance, removing the formed precipitate, ultrafiltering the resulting liquid phase part to obtain as the permeate an aqueous solution of a bifidobacteria-proliferating substance, and if necessary subjecting the permeate to further purification steps, i.e. active carbon or adsorbing resin treatment, electrodialysis and ion exchange resin treatment. By the step of the alkali substance treatment and heating in this invention, permeate flux in the succeeding ultrafiltration step is remarkably enhanced. Further, a bifidobacteria-proliferating substance having a high quality can effectively be obtained by the present purification method.