公开(公告)号：US08087334B2

公开(公告)日：2012-01-03

申请号：US11643922

申请日：2006-12-20

申请人： Tatsuya Miyatani ,  Tetsumasa Ito ,  Hirohito Fujiwara ,  Koji Fujimoto

发明人： Tatsuya Miyatani ,  Tetsumasa Ito ,  Hirohito Fujiwara ,  Koji Fujimoto

IPC分类号： G01N1/06

CPC分类号： G01N1/06 ,  Y10T83/2098 ,  Y10T83/2194 ,  Y10T83/869 ,  Y10T83/929 ,  Y10T83/9454

摘要： A sectioning instrument fabricates a section having an accurate and uniform thickness to be carried to a next step automatically without deforming a surface of an embedded block and while observing the surface of the embedded block. The sectioning instrument includes a sample base for fixing an embedded block, a cutter for fabricating a section by sectioning the embedded block, a carrier for carrying the section, and a feed mechanism for moving the sample base in a predetermined feed direction. The carrier includes a belt, a direction switching portion provided on an upper side of the cutter, and a rear roller. The belt is inserted to between the cutter and the direction switching portion from a rear side of the cutter, folded back to an upper side by the direction switching portion and is reeled back to the rear side of the cutter by the rear roller substantially in parallel with the feed direction of the feed mechanism in a plane view.

摘要翻译： 切割仪器制造具有精确和均匀厚度的部分，以自动地承载到下一步骤，而不会使嵌入块的表面变形，同时观察嵌入块的表面。 切割仪包括用于固定嵌入块的样品基底，用于通过切割嵌入块来制造截面的切割器，用于承载该部分的载体和用于沿预定进给方向移动样品基底的进给机构。 载体包括带，设置在切割器的上侧的方向切换部和后辊。 带从切割器的后侧插入到切割器和方向切换部之间，由方向切换部分折回到上侧，并且通过后辊基本上平行地卷绕回切割器的后侧 进给机构的进给方向在平面图中。

公开(公告)号：US08074547B2

公开(公告)日：2011-12-13

申请号：US11657274

申请日：2007-01-24

申请人： Tetsumasa Ito ,  Tatsuya Miyatani ,  Koji Fujimoto

发明人： Tetsumasa Ito ,  Tatsuya Miyatani ,  Koji Fujimoto

IPC分类号： G01N1/31 ,  G01N1/06 ,  G01N1/04

CPC分类号： G01N1/06 ,  Y10S83/919 ,  Y10T83/04 ,  Y10T83/145 ,  Y10T83/178 ,  Y10T83/222 ,  Y10T83/263 ,  Y10T83/839

摘要： An automatic slicing apparatus reduces the likelihood of failure to make a sliced piece specimen even if continuously operated. The apparatus, on the basis of an exchange command signal, detaches a sample block attached to a cutting base and attaches a new sample block to the cutting base. The apparatus cuts a sliced piece of a predetermined thickness by moving a knife with respect to the sample block having been attached to the cutting base. The apparatus also observes the sliced piece having been cut and judges the sliced piece by comparing an observation data obtained by the observation means and a sample block cut face data. When the apparatus judges that the sliced piece is good, the apparatus transmits an exchange command signal.

摘要翻译： 自动切片装置即使连续操作，也可以降低成型片试样失败的可能性。 该装置基于交换指令信号，将附接到切割基座的样本块分离并将新的样品块附接到切割基部。 该装置通过相对于已经附接到切割基座的样品块移动刀来切割预定厚度的切片。 该装置还观察切片，并通过比较观察装置得到的观察数据和样本块切割面数据来判断切片。 当设备判断切片良好时，装置发送交换命令信号。

公开(公告)号：US07866464B2

公开(公告)日：2011-01-11

申请号：US11829555

申请日：2007-07-27

申请人： Tatsuya Miyatani ,  Koji Fujimoto ,  Tetsumasa Ito

发明人： Tatsuya Miyatani ,  Koji Fujimoto ,  Tetsumasa Ito

IPC分类号： B65G15/30 ,  G01N1/06 ,  G01N35/04

CPC分类号： G01N1/06 ,  G01N1/312 ,  G01N1/4077 ,  G01N35/00009 ,  G01N35/04

摘要： A thin-section conveyor apparatus for transporting thin sections that have been prepared by thinly cutting an embedded block, which transports the thin sections to a liquid bath by mounting them on the upper plane of a conveyor belt having a longitudinal linear body extended along the direction of transportation and a transverse linear body disposed perpendicular to the longitudinal linear body, provided that the density of the transverse linear body for the part on which the thin sections are to be mounted is lower than that of the transverse linear body of the other places. It provides thin sections almost free of entraining bubbles. A thin-section scooping tool and a method for transporting thin sections are also proposed.

摘要翻译： 一种输送薄片输送装置的薄型输送装置，该薄片部分通过薄切割嵌入块来制备，该嵌入块通过将薄壁部分安装到具有沿着方向延伸的纵向线性体的输送带的上平面 并且垂直于纵向线性体设置的横向线状体，其中，用于其上安装有薄壁部分的部分的横向线状体的密度低于其它位置的横向线状体的密度。 它提供了几乎没有夹带气泡的薄部分。 还提出了一种薄型舀取工具和一种输送薄片的方法。

公开(公告)号：US20070204734A1

公开(公告)日：2007-09-06

申请号：US11651714

申请日：2007-01-10

申请人： Tetsumasa Ito ,  Tatsuya Miyatani ,  Koji Fujimoto

发明人： Tetsumasa Ito ,  Tatsuya Miyatani ,  Koji Fujimoto

IPC分类号： G01N1/06 ,  B26D7/10 ,  B26D7/08 ,  G01N1/28

CPC分类号： G01N1/06 ,  G01N1/42 ,  Y10T83/041 ,  Y10T83/263 ,  Y10T83/283

摘要： To fabricate automatically a high quality sliced piece by preventing a temperature change of a surface of an enveloped block, there is provided an automatic sliced piece fabricating apparatus including a fixed base for mounting to fix an enveloped block, cutting means including a cut blade arranged on the fixed base for cutting out a sliced piece from the enveloped block by moving the cut blade and the fixed base relative to each other, a cabinet for containing the fixed base and the cutting means at inside thereof, sliced piece carrying means for carrying the cut-out sliced piece to outside of the cabinet, and temperature adjusting means for adjusting at least a surrounding temperature of the enveloped block to a predetermined temperature by supplying cold wind a temperature of which is controlled from outside at inside of the cabinet.

摘要翻译： 为了通过防止包封块的表面的温度变化来自动制造高质量的切片，提供了一种自动切片制造装置，包括：固定基座，用于安装以固定包封块;切割装置，包括设置在 固定基座，用于通过相对于彼此移动切割刀片和固定基座来从包封块切割切片，用于在其内侧容纳固定基座和切割装置的机壳，用于承载切割的切片片承载装置 以及温度调节装置，用于通过从壳体内部的外部供给温度控制的冷风来调节至少包围的块的周围温度至预定的温度。

公开(公告)号：US20080202308A1

公开(公告)日：2008-08-28

申请号：US12033474

申请日：2008-02-19

申请人： Hirohito Fujiwara ,  Tetsumasa Ito ,  Koji Fujimoto ,  Tatsuya Miyatani

发明人： Hirohito Fujiwara ,  Tetsumasa Ito ,  Koji Fujimoto ,  Tatsuya Miyatani

IPC分类号： B26D7/06

CPC分类号： G01N1/06 ,  Y10T83/6492 ,  Y10T83/9459

摘要： An automatic thin-section manufacturing system for manufacturing thin sections by thinly cutting out an embedded block having embedded therein a biological sample while setting said embedded block at a predetermined rake angle, and said system comprising: a long cutting blade having a cutting edge on one end; a holder disposed in such a manner that it makes the rake angle with respect to the surface of the embedded block; a mounting plane which is provided to the front end of the holder, on which plural cutting blades are mounted and aligned with their cutting edges exposed to the outer side; an adsorptive member provided along the mounting plane, which maintains the posture of the cutting blades by adsorbing the base end side of the cutting blades mounted on the mounting plane; a first pressing member provided to the holder, which presses, among the plural cutting blades that are mounted and aligned on the mounting plane, the cutting blade allocated to the predetermined position against the mounting plane; a conveyor unit which slides out the cutting blades that are linearly aligned on the mounting plane, by sequentially conveying the plural cutting blades to feed them one by one on the mounting plane; a transportation unit which moves the embedded block relative to the holder, such that the cutting blade pressed by the first pressing member cuts out the thin section from the embedded block; and a control unit which, after performing thin sectioning for a predetermined time, exchanging the cutting blade used for the thin sectioning by operating the conveyor unit to slide out the cutting blades.

摘要翻译： 一种自动薄片制造系统，用于通过在将所述嵌入块设置在预定前角处的同时，将嵌入其中的嵌入块嵌入生物样品中而将其切割出来，制造薄片，并且所述系统包括：长切割刀片， 结束; 保持器，其以相对于嵌入块的表面形成前角的方式设置; 安装平面，其设置在所述保持器的前端，多个切割刀片安装在所述保持器的前端上并与其暴露于所述外侧的切割刃对齐; 沿着安装平面设置的吸附构件，其通过吸附安装在安装平面上的切割刀片的基端侧而保持切割刀片的姿势; 设置在所述保持器上的第一按压构件，其在安装和对准所述安装面上的所述多个切割刀片之间按照相对于所述安装平面分配到所述预定位置的所述切割刀片; 输送单元，其通过依次输送多个切割刀片，在安装平面上一个接一个地滑出沿着安装平面线性对准的切割刀片; 运送单元，其使所述嵌入块相对于所述保持架移动，使得由所述第一按压构件按压的所述切割刀片从所述嵌入块切出所述薄部; 以及控制单元，在经过预定时间的薄切片之后，通过操作所述输送单元来更换用于薄切割的切割刀片以滑出切割刀片。

公开(公告)号：US20070204740A1

公开(公告)日：2007-09-06

申请号：US11642475

申请日：2006-12-20

申请人： Tatsuya Miyatani ,  Tetsumasa Ito ,  Koji Fujimoto ,  Eiji Nakano ,  Hirohito Fujiwara

发明人： Tatsuya Miyatani ,  Tetsumasa Ito ,  Koji Fujimoto ,  Eiji Nakano ,  Hirohito Fujiwara

IPC分类号： G01N1/00 ,  G01N1/04

CPC分类号： G01N1/312 ,  G01N1/06 ,  G01N1/31 ,  G01N35/00722 ,  G01N35/0099 ,  G01N2001/362

摘要： To be able to alleviate burden on an operator and automatically fabricate a necessary number of sheets of prepared slides from respective embedded blocks while pertinently interchanging the respective embedded blocks, there is provided an automatic instrument for fabricating prepared slide of tissue section including a store house for storing a plurality of embedded blocks embedded with a living body sample by an embedding medium, cutting means for cutting out a section by cutting the embedded block by a predetermined thickness, first carrying means for putting in and out a selected one of the embedded block to and from the store house and carrying the selected one of the embedded block to a position of being cut by the cutting means, second carrying means for carrying the section to a storage tank stored with a liquid to be floated on a liquid surface, transcribing means for fabricating a prepared slide by transcribing the section floated on the liquid surface onto a base plate, and a control portion for controlling the first carrying means to cut out a necessary number of the sections from the embedded block, thereafter, return the embedded block to the store house, and take out a successively selected one of the embedded block from the store house to be carried to the cut position.

摘要翻译： 为了能够减轻操作者的负担，并且在相应的嵌入块相应地互换的同时自动地制造必要数量的准备好的幻灯片片材，提供了一种用于制造组织部分的准备的幻灯片的自动仪器，其包括存储室 通过嵌入介质存储嵌入生物体样本的多个嵌入块，切割装置，用于通过将嵌入块切割预定厚度来切割部分;第一传送装置，用于将嵌入块中的所选一个插入到所述嵌入块中 并且从储藏室将所选择的嵌入块中的一个运送到由切割装置切割的位置，第二承载装置，用于将存储于待浮动的液体的储存罐运送到液体表面上的转录装置 用于通过将浮在液面上的部分转印到基板上来制造制备的载玻片，以及a 控制部分，用于控制第一携带装置从嵌入块切出必要数量的部分，然后将嵌入块返回到存储室，并从存储器中取出连续选择的嵌入块中的一个 携带到切割位置。

公开(公告)号：US20070157786A1

公开(公告)日：2007-07-12

申请号：US11643922

申请日：2006-12-20

申请人： Tatsuya Miyatani ,  Tetsumasa Ito ,  Hirohito Fujiwara ,  Koji Fujimoto

发明人： Tatsuya Miyatani ,  Tetsumasa Ito ,  Hirohito Fujiwara ,  Koji Fujimoto

IPC分类号： B26D1/00 ,  B26D5/08

CPC分类号： G01N1/06 ,  Y10T83/2098 ,  Y10T83/2194 ,  Y10T83/869 ,  Y10T83/929 ,  Y10T83/9454

摘要： To provide a sectioning instrument capable of fabricating a section having an accurate and uniform thickness to be carried to a next step automatically without deforming a surface of an embedded block and while observing the surface of the embedded block, a sectioning instrument includes a sample base for fixing an embedded block, a cutter for fabricating a section by sectioning the embedded block, carrying means for carrying the section, and a feed mechanism for moving the sample base in a predetermined feed direction, the carrying means includes a belt, a direction switching portion provided on an upper side of the cutter, and a rear roller, the belt is inserted to between the cutter and the direction switching portion from a rear side of the cutter, folded back to an upper side by the direction switching portion and is reeled back to the rear side of the cutter by the rear roller substantially in parallel with the feed direction of the feed mechanism in a plane view thereof.

摘要翻译： 为了提供一种能够制造具有精确且均匀的厚度的部分以便自动承载到下一步骤而不使嵌入块的表面变形并且同时观察嵌入块的表面的切片仪器，切片仪器包括用于 固定嵌入块，用于通过切割嵌入块来制造截面的切割器，用于承载该部分的承载装置和用于沿预定进给方向移动样品基座的进给机构，所述承载装置包括带，方向切换部 设置在切割器的上侧，并且后辊，带从切割器的后侧插入到切割器和方向切换部之间，由方向切换部折回到上侧并被卷回 通过后辊大致与进给机构的进给方向平行的切割器的后侧在其平面图中。

公开(公告)号：US20080044260A1

公开(公告)日：2008-02-21

申请号：US11829555

申请日：2007-07-27

申请人： Tatsuya Miyatani ,  Koji Fujimoto ,  Tetsumasa Ito

发明人： Tatsuya Miyatani ,  Koji Fujimoto ,  Tetsumasa Ito

IPC分类号： G01N35/04

CPC分类号： G01N1/06 ,  G01N1/312 ,  G01N1/4077 ,  G01N35/00009 ,  G01N35/04

摘要： A thin-section conveyor apparatus for transporting thin sections that have been prepared by thinly cutting an embedded block, which transports the thin sections to a liquid bath by mounting them on the upper plane of a conveyor belt having a longitudinal linear body extended along the direction of transportation and a transverse linear body disposed perpendicular to the longitudinal linear body, provided that the density of the transverse linear body for the part on which the thin sections are to be mounted is lower than that of the transverse linear body of the other places. It provides thin sections almost free of entraining bubbles. A thin-section scooping tool and a method for transporting thin sections are also proposed.

摘要翻译： 一种输送薄片输送装置的薄型输送装置，该薄片部分通过薄切割嵌入块来制备，该嵌入块通过将薄壁部分安装到具有沿着方向延伸的纵向线性体的输送带的上平面 并且垂直于纵向线性体设置的横向线状体，其中，用于其上安装有薄壁部分的部分的横向线状体的密度低于其它位置的横向线状体的密度。 它提供了几乎没有夹带气泡的薄部分。 还提出了一种薄型舀取工具和一种输送薄片的方法。

公开(公告)号：US07802507B2

公开(公告)日：2010-09-28

申请号：US11651714

申请日：2007-01-10

申请人： Tetsumasa Ito ,  Tatsuya Miyatani ,  Koji Fujimoto

发明人： Tetsumasa Ito ,  Tatsuya Miyatani ,  Koji Fujimoto

IPC分类号： G01N1/04 ,  G01N1/06

CPC分类号： G01N1/06 ,  G01N1/42 ,  Y10T83/041 ,  Y10T83/263 ,  Y10T83/283

摘要： To fabricate automatically a high quality sliced piece by preventing a temperature change of a surface of an enveloped block, there is provided an automatic sliced piece fabricating apparatus including a fixed base for mounting to fix an enveloped block, cutting means including a cut blade arranged on the fixed base for cutting out a sliced piece from the enveloped block by moving the cut blade and the fixed base relative to each other, a cabinet for containing the fixed base and the cutting means at inside thereof, sliced piece carrying means for carrying the cut-out sliced piece to outside of the cabinet, and temperature adjusting means for adjusting at least a surrounding temperature of the enveloped block to a predetermined temperature by supplying cold wind a temperature of which is controlled from outside at inside of the cabinet.

摘要翻译： 为了通过防止包封块的表面的温度变化来自动制造高质量的切片，提供了一种自动切片制造装置，包括：固定基座，用于安装以固定包封块;切割装置，包括设置在 固定基座，用于通过相对于彼此移动切割刀片和固定基座来从包封块切割切片，用于在其内侧容纳固定基座和切割装置的机壳，用于承载切割的切片片承载装置 以及温度调节装置，用于通过从壳体内部的外部供给温度控制的冷风来调节至少包围的块的周围温度至预定的温度。

公开(公告)号：US20080044315A1

公开(公告)日：2008-02-21

申请号：US11880388

申请日：2007-07-19

申请人： Koji Fujimoto ,  Tetsumasa Ito ,  Tatsuya Miyatani

发明人： Koji Fujimoto ,  Tetsumasa Ito ,  Tatsuya Miyatani

IPC分类号： B01L3/00

CPC分类号： G01N1/36 ,  B01L3/545 ,  B01L2300/02 ,  G01N2001/315 ,  G01N2001/366

摘要： An embedding cassette to which an identification code can be engraved using a laser beam, which enables display of a clear identification code free from peeling off and unaffected by paraffin; the embedding cassette comprises a cassette body having formed thereon an open concave enclosing part having a flat plane for placing therein the biological sample, a lid part fixed freely detachable to the cassette body, which shuts the concave enclosing part, and a thin film layer provided on the flat plane, with a color at least differing in value with respect to that of the cassette body, provided that the thin film layer displays the identification code by being engraved upon irradiating a laser beam.

摘要翻译： 使用激光束能够识别识别码的嵌入盒，能够显示不被剥离并且不受石蜡影响的清晰识别码; 所述嵌入盒包括：盒本体，其上形成有具有用于放置所述生物样品的平坦平面的敞开的凹入封闭部分，固定在所述盒体上的可自由拆卸的盖部分，所述盖部分封闭所述凹形封闭部分;以及薄膜层， 如果薄膜层通过在照射激光束时被雕刻来显示识别码，则在平面上具有至少与盒体相差不同的颜色。