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1.
公开(公告)号:US20090186364A1
公开(公告)日:2009-07-23
申请号:US12223975
申请日:2007-02-15
CPC分类号: G01N33/5432 , C12N15/86 , C12N15/88 , C12N2710/14143 , C12N2810/855 , G01N33/564 , G01N33/56983 , G01N2333/01 , G01N2469/20
摘要: [PROBLEMS] To provide a method for preparation of recombinant proteoliposomes suitable for diagnostic applications, a detection plate coated with the recombinant proteoliposomes, a detection kit and so on.[PROBLEM-SOLVING MEANS] Recombinant proteoliposomes are prepared by fusion of budded virus particles of a recombinant baculovirus, expressing a target membrane receptor (such as human thyroid-stimulating hormone receptor, acetylcholine receptor, insulin receptor, β1 adrenergic receptor, asialoglycoprotein receptor, etc., each participating in an autoantibody-related disease), with liposomes. Compared with the recombinant baculoviruses, these proteoliposomes have an improved ability to bind to an autoantibody and makes it possible to produce easily a kit for its detection.
摘要翻译: [问题]提供一种适用于诊断应用的重组蛋白脂质体的制备方法,用重组蛋白脂质体包被的检测板,检测试剂盒等。 [问题解决方案]重组蛋白脂质体通过表达靶膜受体(如人甲状腺激素受体,乙酰胆碱受体,胰岛素受体,β1肾上腺素能受体,脱唾液酸糖蛋白受体等)的重组杆状病毒的发芽病毒颗粒的融合而制备 ,各自参与自身抗体相关疾病),与脂质体。 与重组杆状病毒相比,这些蛋白脂质体具有改进的与自身抗体结合的能力,并且使得可以容易地制备用于其检测的试剂盒。
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2.
公开(公告)号:US08563291B2
公开(公告)日:2013-10-22
申请号:US12223975
申请日:2007-02-15
CPC分类号: G01N33/5432 , C12N15/86 , C12N15/88 , C12N2710/14143 , C12N2810/855 , G01N33/564 , G01N33/56983 , G01N2333/01 , G01N2469/20
摘要: [PROBLEMS] To provide a method for preparation of recombinant proteoliposomes suitable for diagnostic applications, a detection plate coated with the recombinant proteoliposomes, a detection kit and so on.[PROBLEM-SOLVING MEANS] Recombinant proteoliposomes are prepared by fusion of budded virus particles of a recombinant baculovirus, expressing a target membrane receptor (such as human thyroid-stimulating hormone receptor, acetylcholine receptor, insulin receptor, β1 adrenergic receptor, asialoglycoprotein receptor, etc., each participating in an autoantibody-related disease), with liposomes. Compared with the recombinant baculoviruses, these proteoliposomes have an improved ability to bind to an autoantibody and makes it possible to produce easily a kit for its detection.
摘要翻译: [问题]提供一种适用于诊断应用的重组蛋白脂质体的制备方法,用重组蛋白脂质体包被的检测板,检测试剂盒等。 [问题解决方案]重组蛋白脂质体通过表达靶膜受体(如人甲状腺激素受体,乙酰胆碱受体,胰岛素受体,β1肾上腺素能受体,脱唾液酸糖蛋白受体等)的重组杆状病毒的发芽病毒颗粒的融合而制备 ,各自参与自身抗体相关疾病),与脂质体。 与重组杆状病毒相比,这些蛋白脂质体具有改进的与自身抗体结合的能力,并且使得可以容易地制备用于其检测的试剂盒。
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公开(公告)号:US06255313B1
公开(公告)日:2001-07-03
申请号:US09341191
申请日:1999-07-06
申请人: Kenichi Suzuki , Kouji Imamura , Susumu Morioka , Shigeo Tanaka
发明人: Kenichi Suzuki , Kouji Imamura , Susumu Morioka , Shigeo Tanaka
IPC分类号: A61K31505
CPC分类号: A61Q7/00 , A61K8/4953 , Y10S514/88
摘要: A sustained hair growth preparation comprising minoxidil and dipropylene glycol makes it possible to retain the absorbed minoxidil in the dermis and to increase the concentration of the minoxidil around the hair bulbs which are the hair growing sites, thereby making it possible to give a sufficient hair growth effect.
摘要翻译: 包含米诺地尔和二丙二醇的持续毛发生长制剂使得可以将吸收的米诺地尔保留在真皮中,并且增加作为毛发生长部位的毛发周围的米诺地尔的浓度,从而使得可以产生足够的毛发生长 影响。
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