公开(公告)号：US20250009656A1

公开(公告)日：2025-01-09

申请号：US18710555

申请日：2022-11-15

Applicant: The Board of Regents of The University of Texas System

Inventor： Jinming GAO ,  Gang HUANG ,  Zhichen SUN ,  Qiang FENG ,  Wei LI

IPC: A61K9/107 ,  A61K38/20 ,  A61K47/34 ,  A61K47/64 ,  A61K47/68 ,  C08F293/00

Abstract: Ultra pH sensitive (UPS) micelles encapsulating cytokines are provided that provide lower toxicity and higher efficacy compositions and methods for treating cancer with those compositions.

公开(公告)号：US20210338579A1

公开(公告)日：2021-11-04

申请号：US17239742

申请日：2021-04-26

Applicant: The Board of Regents of the University of Texas System

Inventor： Jinming GAO ,  Tongyi HUANG ,  Qiang FENG ,  Baran SUMER

IPC: A61K9/107 ,  A61K47/32 ,  A61K47/34 ,  A61K31/519 ,  A61K31/5025 ,  A61K45/06 ,  A61P35/00

Abstract: Described herein are therapeutic pH responsive compositions comprising a block copolymer and a therapeutic agent useful for the treatment of cancer.