专利检索 ap:("The Board of Trustees of the Leland Stanford Junior University" OR "The United States Government as represented by the Department of Veterans Affairs") AND inv:"Zurab Siprashvili" 第 1 页

1.

发明授权
Gene therapy for recessive dystrophic epidermolysis bullosa using genetically corrected autologous keratinocytes 有权

公开(公告)号：US12110504B2

公开(公告)日：2024-10-08

申请号：US18501837

申请日：2023-11-03

申请人： The Board of Trustees of the Leland Stanford Junior University , The United States Government as represented by the Department of Veterans Affairs

发明人： Zurab Siprashvili , Ngon T. Nguyen , M. Peter Marinkovich , Jean Tang , Alfred T. Lane , Paul A. Khavari

IPC分类号： A61K38/39 , A61K48/00 , A61L27/00 , A61L27/36 , C12N5/00 , C12N5/071

CPC分类号： C12N5/0629 , A61K48/0058 , A61K48/0075 , A61K48/0091 , C12N2510/00 , C12N2760/16043

摘要： Methods are provided for the cell-based delivery of collagen VII for the treatment of Epidermolysis Bullosa and corneal erosion. The disclosure also provides a composition and a pharmaceutical composition comprises, comprise, or alternatively consist essentially of, or yet further consist of a keratinocyte sheet or a corneal cell sheet.

2.

发明公开
GENE THERAPY FOR RECESSIVE DYSTROPHIC EPIDERMOLYSIS BULLOSA USING GENETICALLY CORRECTED AUTOLOGOUS KERATINOCYTES 审中-公开

公开(公告)号：US20240067926A1

公开(公告)日：2024-02-29

申请号：US18501837

申请日：2023-11-03

申请人： The Board of Trustees of the Leland Stanford Junior University , The United States Government as represented by the Department of Veterans Affairs

发明人： Zurab Siprashvili , Ngon T. Nguyen , M. Peter Marinkovich , Jean Tang , Alfred T. Lane , Paul A. Khavari

IPC分类号： C12N5/071 , A61K48/00

CPC分类号： C12N5/0629 , A61K48/0058 , A61K48/0075 , A61K48/0091 , C12N2510/00 , C12N2760/16043

摘要： Methods are provided for the cell-based delivery of collagen VII for the treatment of Epidermolysis Bullosa and corneal erosion. The disclosure also provides a composition and a pharmaceutical composition comprises, comprise, or alternatively consist essentially of, or yet further consist of a keratinocyte sheet or a corneal cell sheet.

3.

发明申请
GENE THERAPY FOR RECESSIVE DYSTROPHIC EPIDERMOLYSIS BULLOSA USING GENETICALLY CORRECTED AUTOLOGOUS KERATINOCYTES 审中-公开

公开(公告)号：US20190382724A1

公开(公告)日：2019-12-19

申请号：US16066253

申请日：2017-01-03

申请人： The Board of Trustees of the Leland Stanford Junior University , U.S. GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS

发明人： Zurab Siprashvili , Ngon T. Nguyen , M. Peter Marinkovich , Jean Tang , Alfred T. Lane , Paul A. Khavari

IPC分类号： C12N5/071 , A61K48/00

摘要： Methods are provided for the cell-based delivery of collagen VII for the treatment of Epidermolysis Bullosa and corneal erosion. The disclosure also provides a composition and a pharmaceutical composition comprises, comprise, or alternatively consist essentially of, or yet further consist of a keratinocyte sheet or a corneal cell sheet.