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公开(公告)号:US11717418B2
公开(公告)日:2023-08-08
申请号:US17040453
申请日:2019-03-26
发明人: Alan Dang , Alexis Dang , Wenhan Chang , Alfred Li
CPC分类号: A61F2/447 , A61F2/3094 , A61F2002/3092 , A61F2002/3093 , A61F2002/30593 , A61F2002/30985 , A61F2002/4495 , A61F2310/00023 , A61F2310/00029 , A61F2310/00077 , A61F2310/00161
摘要: Novel articles of manufacture based comprising lattices based on trabecular bone, having a plurality of plates and interconnecting rods. The trabecular bone-inspired lattice may be designed based on the general alignment of plates and rods found in trabecular bone, including anisotropic lattices having one or more predominant axes of mechanical strength. Lumbar fusion implants and other implants are provided having a trabecular bone inspired lattice in which bone graft material may be packed and providing a scaffold for bone fusion and growth. The implants may be based on bone structures having a predominant axis of mechanical strength and may be deployed in sites with the predominant axis of mechanical strength aligned with the primary axis of mechanical stress, such as in the the spine.
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公开(公告)号:US20210022882A1
公开(公告)日:2021-01-28
申请号:US17040453
申请日:2019-03-26
发明人: Alan Dang , Alexis Dang , Wenhan Chang , Alfred Li
摘要: Novel articles of manufacture based comprising lattices based on trabecular bone, having a plurality of plates and interconnecting rods. The trabecular bone-inspired lattice may be designed based on the general alignment of plates and rods found in trabecular bone, including anisotropic lattices having one or more predominant axes of mechanical strength. Lumbar fusion implants and other implants are provided having a trabecular bone inspired lattice in which bone graft material may be packed and providing a scaffold for bone fusion and growth. The implants may be based on bone structures having a predominant axis of mechanical strength and may be deployed in sites with the predominant axis of mechanical strength aligned with the primary axis of mechanical stress, such as in the the spine.
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公开(公告)号:US11951136B2
公开(公告)日:2024-04-09
申请号:US16772078
申请日:2018-12-12
申请人: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA , U.S. GOVERNMENT REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS
发明人: Casey Ward , Qizhi Tang , Peter Stock , Gaetano Faleo , Gopika Nair , Matthias Hebrok , Wenhan Chang , Thuy Vo , Jeffrey A. Bluestone , Eleonora De Klerk
CPC分类号: A61K35/55 , A61K9/0019 , A61K9/0024 , A61K35/39 , A61P3/10 , C12N5/0617 , C12N5/0676 , A61K2300/00 , C12N2506/02 , C12N2506/078
摘要: Provided herein, inter alia, are methods and compositions for treating diabetes mellitus comprising co-transplantation of an insulin-producing cell and a cell derived from a parathyroid gland (PTG), a CD34+ cell derived from a parathyroid gland, a CD34+ cell derived from a stem cell, or other progenitor cell-derived CD34+ cell.
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