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公开(公告)号：US10967055B2
公开(公告)日：2021-04-06
申请号：US16113924
申请日：2018-08-27
Applicant: The Texas A&M University System
Inventor： James E. Samuel , Erin J. Van Schaik , Anthony E. Gregory
Abstract: A vaccine includes at least one bacterial antigen capable of producing an immune response in a host when the vaccine is administered at a dose that is sufficient for preventing or treating Q fever in the host. The vaccine composition confers immunity against Q fever without the reactogenic side effects observed in prior art vaccines.
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公开(公告)号：US20250123277A1
公开(公告)日：2025-04-17
申请号：US18721703
申请日：2022-12-23
Applicant: The Texas A&M University System
Inventor： Arum Han , Rohit Kunal Gupte , Jing Dai , Paul J. de Figueiredo , Erin J. Van Schaik
IPC: G01N33/569 , C12N1/20 , C12N11/04
Abstract: In an embodiment. the present disclosure pertains to environmental biospecimen recovery after in-droplet gel encapsulation (eBRIDGE) platforms for co-culturing multiple microorganisms in gel microspheres and then transferring single-cell-derived clonal populations from within the gel microspheres into separate water-in-oil emulsion droplets for further processing and analysis. In some embodiments. the gel-encapsulated bacteria are released by lysing the gel matrix using an enzyme. The methods of the present disclosure provide a single workflow that goes from environmental microbial harvesting and amplification to functional interrogation of their characteristics.
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公开(公告)号：US20190083598A1
公开(公告)日：2019-03-21
申请号：US16113924
申请日：2018-08-27
Applicant: The Texas A&M University System
Inventor： James E. Samuel , Erin J. Van Schaik , Anthony E. Gregory
Abstract: A vaccine includes at least one bacterial antigen capable of producing an immune response in a host when the vaccine is administered at a dose that is sufficient for preventing or treating Q fever in the host. The vaccine composition confers immunity against Q fever without the reactogenic side effects observed in prior art vaccines.
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