公开(公告)号：US09913700B2

公开(公告)日：2018-03-13

申请号：US14881922

申请日：2015-10-13

申请人： The Texas A&M University System

发明人： Xiaohua Liu ,  Chi Ma ,  Tiejun Qu

IPC分类号： B23K26/55 ,  B29C71/04 ,  A61C8/02 ,  D01D5/00 ,  B29C69/00 ,  B23K26/00 ,  A61C8/00

CPC分类号： A61C8/0006 ,  A61C8/0012 ,  B23K26/55 ,  B29C69/001 ,  D01D5/0023 ,  D01D5/003 ,  D01D5/0038 ,  D01D5/0076

摘要： The present invention relates to a biomimetic matrix for providing structural support and scaffolding that allows for regeneration of dentin, pulp, and periodontal tissues. A method of making the biomimetic matrix provides the ability to select both a size of a pore or tubule formed in the biomimetic matrix and a density of pores or tubules disposed throughout the biomimetic matrix. The present invention discloses an approach of successful tubular dentin regeneration both in vitro and in vivo using the biomimetic matrix.

公开(公告)号：US20160184058A1

公开(公告)日：2016-06-30

申请号：US14881922

申请日：2015-10-13

申请人： The Texas A&M University System

发明人： Xiaohua Liu ,  Chi Ma ,  Tiejun Qu

IPC分类号： A61C8/02

CPC分类号： A61C8/0006 ,  A61C8/0012 ,  B23K26/55 ,  B29C69/001 ,  D01D5/0023 ,  D01D5/003 ,  D01D5/0038 ,  D01D5/0076

摘要： The present invention relates to a biomimetic matrix for providing structural support and scaffolding that allows for regeneration of dentin, pulp, and periodontal tissues. A method of making the biomimetic matrix provides the ability to select both a size of a pore or tubule formed in the biomimetic matrix and a density of pores or tubules disposed throughout the biomimetic matrix. The present invention discloses an approach of successful tubular dentin regeneration both in vitro and in vivo using the biomimetic matrix.

摘要翻译： 本发明涉及一种用于提供结构支持和支架的仿生基质，其允许牙本质，牙髓和牙周组织的再生。 制备仿生基质的方法提供了选择在仿生基质中形成的孔或小管的尺寸以及设置在整个仿生基质中的孔或小管的密度的能力。 本发明公开了使用仿生基质在体外和体内成功管状牙本质再生的方法。