公开(公告)号：US20190116666A1

公开(公告)日：2019-04-18

申请号：US16214601

申请日：2018-12-10

Applicant: The Trustees of the University of Pennsylvania

Inventor： Alan T. Johnson, JR. ,  Rajatesh R. Gudibande ,  Zhengqing John Qi

IPC: H05K1/09 ,  H01L29/16 ,  H05K3/20 ,  H05K3/06 ,  H05K3/12 ,  H05K1/03

Abstract: The present invention provides methods for fabricating graphene workpieces. The present invention also provides for products produced by the methods of the present invention and for apparatuses used to perform the methods of the present invention.

公开(公告)号：US20200170108A1

公开(公告)日：2020-05-28

申请号：US16752421

申请日：2020-01-24

Applicant: The Trustees of the University of Pennsylvania

Inventor： Alan T. Johnson, JR. ,  Rajatesh R. Gudibande ,  Zhengqing John Qi

IPC: H05K1/09 ,  H05K3/12 ,  H05K3/06 ,  H05K1/03 ,  H01L29/16 ,  H05K3/20 ,  B33Y80/00 ,  H01L29/786

Abstract: The present invention provides methods for fabricating graphene workpieces. The present invention also provides for products produced by the methods of the present invention and for apparatuses used to perform the methods of the present invention.

公开(公告)号：US20250027900A1

公开(公告)日：2025-01-23

申请号：US18907696

申请日：2024-10-07

Applicant: The Trustees of the University of Pennsylvania

Inventor： Alan T. Johnson, JR. ,  Jinglei Ping

IPC: G01N27/30 ,  G01N27/36 ,  G01N27/416

Abstract: Provided are devices and methods for a rapid, non-perturbative and energy-efficient technique for pH sensing based on a flexible graphene electrode. This technique does not require the application of gate voltage or source-drain bias, and demonstrates fast pH-characterization with precision. The disclosed technology is suitable for in vivo monitoring of tumor-induced pH variation in tissues and detection of pH changes as required in a DNA sequencing system.

公开(公告)号：US20240319160A1

公开(公告)日：2024-09-26

申请号：US18504369

申请日：2023-11-08

Applicant: The Trustees of the University of Pennsylvania

Inventor： Alan T. Johnson, JR. ,  Jinglei Ping ,  Steven Vitale ,  Chengyu Wen

IPC: G01N33/18 ,  G01N27/04

CPC classification number: G01N33/1813 ,  G01N27/04 ,  G01N33/1826 ,  G01N2410/00

Abstract: Provided are aptamer-functionalized graphene sensors, capable of detecting various analytes, including toxins, at comparatively low concentrations. Also provided are methods of fabricating and using such aptamer-functionalized graphene sensors.

公开(公告)号：US20230051545A1

公开(公告)日：2023-02-16

申请号：US17711134

申请日：2022-04-01

Applicant: The Trustees of the University of Pennsylvania

Inventor： Alan T. Johnson, JR. ,  Jinglei Ping

IPC: G01N27/30 ,  G01N27/416

Abstract: Provided are devices and methods for a rapid, non-perturbative and energy-efficient technique for pH sensing based on a flexible graphene electrode. This technique does not require the application of gate voltage or source-drain bias, and demonstrates fast pH-characterization with precision. The disclosed technology is suitable for in vivo monitoring of tumor-induced pH variation in tissues and detection of pH changes as required in a DNA sequencing system.

公开(公告)号：US20230337358A1

公开(公告)日：2023-10-19

申请号：US18047689

申请日：2022-10-19

Applicant: The Trustees of the University of Pennsylvania

Inventor： Alan T. Johnson, JR. ,  Rajatesh R. Gudibande ,  Zhengqing John Qi

IPC: H05K1/09 ,  H05K3/20 ,  H01L29/16 ,  H01L29/786 ,  B33Y80/00 ,  H05K1/03 ,  H05K3/06 ,  H05K3/12

CPC classification number: H05K1/09 ,  H05K3/20 ,  H01L29/1606 ,  H01L29/78684 ,  B33Y80/00 ,  H05K1/0306 ,  H05K3/06 ,  H05K3/1216 ,  H05K3/125 ,  H05K3/1275 ,  H05K2201/0323 ,  H05K2203/1338 ,  H01G11/32

Abstract: The present invention provides methods for fabricating graphene workpieces. The present invention also provides for products produced by the methods of the present invention and for apparatuses used to perform the methods of the present invention.

公开(公告)号：US20220011302A1

公开(公告)日：2022-01-13

申请号：US17473412

申请日：2021-09-13

Applicant: The Trustees of the University of Pennsylvania

Inventor： Alan T. Johnson, JR. ,  Ye Lu ,  Joseph J. Mitala, JR. ,  Bohdana Discher ,  Brett R. Goldsmith

IPC: G01N33/543 ,  G01N33/58

Abstract: Provided are devices and methods featuring a nanoelectronic interface between graphene devices (for example, field effect transistors or FETs) and biomolecules such as proteins, which in turn provides a pathway for production of bioelectronic devices that combine functionalities of the biomolecular and inorganic components. In one exemplary application, one may functionalize graphene FETs with fluorescent proteins to yield hybrids that respond to light at wavelengths defined by the optical absorption spectrum of the protein. The devices may also include graphene in electronic communication with a bio-molecule that preferentially binds to a particular analyte.