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公开(公告)号：US11951217B2
公开(公告)日：2024-04-09
申请号：US17750108
申请日：2022-05-20
申请人： The United States of America, as represented by the Secretary, Department of Health and Human Services , The University of Strathclyde
CPC分类号： A61L2/0052 , A61L2/084 , A61L2202/122 , A61L2202/22
摘要： Disclosed herein are methods and devices for the inactivation of pathogens (e.g., bacteria, viruses, etc.) in ex vivo stored blood products, such as plasma and/or platelets, by means of directing visible light radiation from an illuminating device into blood product storage containers in order to achieve effective pathogen inactivation without the presence of an added photosensitising agent in the blood product. An exemplary apparatus includes a control unit that operates a light source that emits light in the wavelength region of about 380-500 nm which is directed onto blood product storage bags at sufficient intensity to penetrate the bag material and the opaque blood product therein in order to inactivate pathogens in the blood product but at dose levels that cause no significant detrimental effects on the blood product.
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2.发明公开公开(公告)号：US20240252697A1
公开(公告)日：2024-08-01
申请号：US18629098
申请日：2024-04-08
申请人： The United States of America, as represented by the Secretary, Department of Health and Human Se , The University of Strathclyde
CPC分类号： A61L2/0052 , A61L2/084 , A61L2202/122 , A61L2202/22
摘要： Disclosed herein are methods and devices for the inactivation of pathogens (e.g., bacteria, viruses, etc.) in ex vivo stored blood products, such as plasma and/or platelets, by means of directing visible light radiation from an illuminating device into blood product storage containers in order to achieve effective pathogen inactivation without the presence of an added photosensitising agent in the blood product. An exemplary apparatus includes a control unit that operates a light source that emits light in the wavelength region of about 380-500 nm which is directed onto blood product storage bags at sufficient intensity to penetrate the bag material and the opaque blood product therein in order to inactivate pathogens in the blood product but at dose levels that cause no significant detrimental effects on the blood product.
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公开(公告)号：US20220273834A1
公开(公告)日：2022-09-01
申请号：US17750108
申请日：2022-05-20
申请人： The United States of America, as represented by the Secretary, Department of Health and Human Servic , The University of Strathclyde
摘要： Disclosed herein are methods and devices for the inactivation of pathogens (e.g., bacteria, viruses, etc.) in ex vivo stored blood products, such as plasma and/or platelets, by means of directing visible light radiation from an illuminating device into blood product storage containers in order to achieve effective pathogen inactivation without the presence of an added photosensitising agent in the blood product. An exemplary apparatus includes a control unit that operates a light source that emits light in the wavelength region of about 380-500 nm which is directed onto blood product storage bags at sufficient intensity to penetrate the bag material and the opaque blood product therein in order to inactivate pathogens in the blood product but at dose levels that cause no significant detrimental effects on the blood product.
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4.发明申请公开(公告)号：US20190070323A1
公开(公告)日：2019-03-07
申请号：US15765424
申请日：2016-09-29
申请人： The US of America, as represented by the Secretary Dept. of Health and Human Servics , The University of Strathclyde
摘要： Disclosed herein are methods and devices for the inactivation of pathogens (e.g., bacteria, viruses, etc.) in ex vivo stored blood products, such as plasma and/or platelets, by means of directing visible light radiation from an illuminating device into blood product storage containers in order to achieve effective pathogen inactivation without the presence of an added photosensitising agent in the blood product. An exemplary apparatus includes a control unit that operates a light source that emits light in the wavelength region of about 380-500 nm which is directed onto blood product storage bags at sufficient intensity to penetrate the bag material and the opaque blood product therein in order to inactivate pathogens in the blood product but at dose levels that cause no significant detrimental effects on the blood product.
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