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公开(公告)号:US20200263136A1
公开(公告)日:2020-08-20
申请号:US16762447
申请日:2018-11-08
申请人: The United States of America,as represented by the Secretary,Department of Health and Human Services
IPC分类号: C12N5/0789 , A61K35/28
摘要: Disclosed are methods of preparing CD34+CD43+ hematopoietic progenitor cells (HPC) in vitro according to embodiments of the invention. Also disclosed are methods of differentiating CD34+CD43+ hematopoietic progenitor cells to hematopoietic lineage cells according to embodiments of the invention. Also disclosed are methods of treating or preventing a condition in a mammal, e.g., cancer, according to embodiments of the invention.
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公开(公告)号:US12037607B2
公开(公告)日:2024-07-16
申请号:US16762447
申请日:2018-11-08
IPC分类号: C12N5/0789 , A61K35/28
CPC分类号: C12N5/0647 , A61K35/28 , C12N2500/98 , C12N2501/115 , C12N2501/125 , C12N2501/135 , C12N2501/145 , C12N2501/155 , C12N2501/165 , C12N2501/20 , C12N2501/22 , C12N2501/2303 , C12N2501/2306 , C12N2501/24 , C12N2501/25 , C12N2501/415 , C12N2502/00 , C12N2506/45 , C12N2513/00 , C12N2531/00
摘要: Disclosed are methods of preparing CD34+CD43+ hematopoietic progenitor cells (HPC) in vitro according to embodiments of the invention. Also disclosed are methods of differentiating CD34+CD43+ hematopoietic progenitor cells to hematopoietic lineage cells according to embodiments of the invention. Also disclosed are methods of treating or preventing a condition in a mammal, e.g., cancer, according to embodiments of the invention.
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公开(公告)号:US20230036952A1
公开(公告)日:2023-02-02
申请号:US17790939
申请日:2021-01-07
申请人: The United States of America,as represented by the Secretary,Department of Health and Human Services
IPC分类号: C12N5/0783 , A61P35/00 , A61P37/02
摘要: Provided are methods of producing an isolated population of T cells for adoptive cell therapy. Also provided are related isolated populations of cells, pharmaceutical compositions, and methods of treating or preventing cancer, infections, and autoimmune conditions in a patient.
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