专利检索 ap:("Thomas Albert Engler" OR "Kelly Wayne Furness" OR "Sushant Malhotra" OR "Stephen Lyle Briggs" OR "Harold Burns Brooks" OR "David K yes Clawson" OR "Concepcion Sanchez-Martinez" OR "Faming Zhang" OR "Guoxin Zhu") AND inv:"Stephen Lyle Briggs" 第 1 页

1.

发明授权
Methods and compounds for treating proliferative diseases 失效
标题翻译：治疗增殖性疾病的方法和化合物

公开(公告)号：US07109229B2

公开(公告)日：2006-09-19

申请号：US10344245

申请日：2001-09-24

申请人： Thomas Albert Engler , Kelly Wayne Furness , Sushant Malhotra , Stephen Lyle Briggs , Harold Burns Brooks , David K yes Clawson , Concepcion Sanchez-Martinez , Faming Zhang , Guoxin Zhu

发明人： Thomas Albert Engler , Kelly Wayne Furness , Sushant Malhotra , Stephen Lyle Briggs , Harold Burns Brooks , David K yes Clawson , Concepcion Sanchez-Martinez , Faming Zhang , Guoxin Zhu

IPC分类号： A61K31/40 , C07D481/00

CPC分类号： C07D403/14 , C07D487/14

摘要： The compounds disclosed herein are indolocarbazoles of Formula (I), which are potent CDK4 inhibitors, and are useful in the treatment of cell proliferative disorders, including cancer. Formula (I).

摘要翻译： 本文公开的化合物是式（I）的吲哚并唑，其是有效的CDK4抑制剂，并且可用于治疗包括癌症的细胞增殖性疾病。式（I）。