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公开(公告)号：US07947301B2
公开(公告)日：2011-05-24
申请号：US12104932
申请日：2008-04-17
CPC分类号： A61K31/65 , A61L27/54 , A61L29/16 , A61L31/16 , A61L2300/406 , A61L2300/602
摘要： Anti-infective articles capable of preventing infection associated with implantation of medical devices include low levels of anti-infective agents, may cover only a fraction of the portion of the medical device and be effective, or may rapidly elute anti-infective agent, without sustained elution, and still be effective.
摘要翻译： 能够预防与植入医疗装置相关的感染的抗感染性制品包括低水平的抗感染剂，可以仅覆盖该部分医疗装置的一部分并且有效，或可以快速洗脱抗感染剂，而不会持续 洗脱，仍然有效。
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公开(公告)号：US08337877B2
公开(公告)日：2012-12-25
申请号：US13083983
申请日：2011-04-11
IPC分类号： A61K9/00 , A61K31/496 , A61P31/00
CPC分类号： A61K31/65 , A61L27/54 , A61L29/16 , A61L31/16 , A61L2300/406 , A61L2300/602
摘要： Anti-infective articles capable of preventing infection associated with implantation of medical devices include low levels of anti-infective agents, may cover only a fraction of the portion of the medical device and be effective, or may rapidly elute anti-infective agent, without sustained elution, and still be effective.
摘要翻译： 能够预防与植入医疗装置相关的感染的抗感染性制品包括低水平的抗感染剂，可以仅覆盖该部分医疗装置的一部分并且有效，或可以快速洗脱抗感染剂，而不会持续 洗脱，仍然有效。
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公开(公告)号：US20110189256A1
公开(公告)日：2011-08-04
申请号：US13083983
申请日：2011-04-11
IPC分类号： A61K9/00 , A61K31/496 , A61P31/00
CPC分类号： A61K31/65 , A61L27/54 , A61L29/16 , A61L31/16 , A61L2300/406 , A61L2300/602
摘要： Anti-infective articles capable of preventing infection associated with implantation of medical devices include low levels of anti-infective agents, may cover only a fraction of the portion of the medical device and be effective, or may rapidly elute anti-infective agent, without sustained elution, and still be effective.
摘要翻译： 能够预防与植入医疗装置相关的感染的抗感染性制品包括低水平的抗感染剂，可以仅覆盖该部分医疗装置的一部分并且有效，或可以快速洗脱抗感染剂，而不会持续 洗脱，仍然有效。
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公开(公告)号：US09480643B2
公开(公告)日：2016-11-01
申请号：US12644094
申请日：2009-12-22
IPC分类号： A61K9/00
CPC分类号： A61K9/0024
摘要： Described herein are implantable composites, articles comprising the composites, implant devices comprising the composites, and methods of making and using same, including point of use methods.
摘要翻译： 本文描述的是可植入复合材料，包含复合材料的制品，包括复合材料的植入装置，以及制造和使用它们的方法，包括使用方法。
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公开(公告)号：US20090125089A1
公开(公告)日：2009-05-14
申请号：US12118598
申请日：2008-05-09
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/05 , A61N1/0551
摘要： The invention is an electrophysiology lead body comprising two or more longitudinal elements, each having an outer surface, the longitudinal elements comprising electrical insulation material, the electrical insulation material consisting essentially of fluoropolymer; at least one conductor disposed within at least one of the longitudinal elements; and a cover consisting essentially of fluoropolymer, wherein the cover surrounds the longitudinal elements.
摘要翻译： 本发明是包括两个或更多个纵向元件的电生理学引线体，每个纵向元件具有外表面，纵向元件包括电绝缘材料，电绝缘材料基本上由氟聚合物组成; 布置在所述纵向元件中的至少一个中的至少一个导体; 以及基本上由氟聚合物组成的盖，其中所述盖围绕所述纵向元件。
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公开(公告)号：US6066166A
公开(公告)日：2000-05-23
申请号：US143504
申请日：1998-08-28
IPC分类号： A61N1/05
CPC分类号： A61N1/0563
摘要： An implantable cardioversion/defibrillation lead having an elongated insulative lead body carrying a tip electrode located at its distal end and a cardioversion/defibrillation electrode located on the lead body, proximal to the tip electrode. An elongated conductor coupled to the tip electrode extends proximally within the lead body. At the proximal end of the lead body is a first connector assembly carrying a first connector and a second connector assembly carrying a second connector. An elongated, stranded or cabled conductor is coupled to the cardioversion/defibrillation electrode and to the second connector and extends uninterrupted therebetween. A cylindrical transition member is coupled to the first connector by means of a coiled conductor. A press-fit sleeve having a longitudinal lumen extending therethrough compresses the stranded or conductor between the press-fit sleeve and the transition member to provide electrical interconnection between the stranded or cabled conductor and the transition member.
摘要翻译： 植入式心脏复律/除颤引线，其具有承载位于其远端的尖端电极的细长绝缘引线体和位于所述引线主体上的靠近所述尖端电极的心脏复律/除颤电极。 耦合到尖端电极的细长导体在引线体内向近侧延伸。 在引线体的近端处是承载第一连接器的第一连接器组件和承载第二连接器的第二连接器组件。 细长的，绞合的或有线的导体耦合到心脏复律/除颤电极和第二连接器并且在它们之间不间断地延伸。 圆柱形过渡构件通过线圈导体连接到第一连接器。 具有延伸通过其延伸的纵向内腔的压入套筒压缩压配合套筒和过渡构件之间的绞合或导体，以提供绞合或电缆导体与过渡构件之间的电互连。
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公开(公告)号：US6016436A
公开(公告)日：2000-01-18
申请号：US938269
申请日：1997-09-26
CPC分类号： A61N1/0573 , A61N1/0565 , A61N2001/0578 , A61N2001/058
摘要： An implantable electrical lead of the type which has an insulative rigid electrode head carrying an advanceable helical electrode. The electrode head is mounted toan elongated insulative lead body which is less rigid than the electrode head and which carries an extensible conductor coupled to the helical electrode and an inextensible conductor coupled to the proximal end of the lead body. A second electrode is mounted to said lead body adjacent the electrode head and is coupled to the inextensible conductor by a conductive sleeve which is mechanically coupled to electrode head so that proximally directed traction forces applied to the lead body are applied by the inextensible conductor directly to the electrode head.
摘要翻译： 一种具有绝缘刚性电极头的可植入电引线，其具有可推进的螺旋电极。 电极头安装在细长的绝缘引线体上，其长度比电极头刚性小，并且其具有连接到螺旋电极的可延伸导体和耦合到引线本体的近端的不可伸展的导体。 第二电极被安装到邻近电极头的所述引线体上，并且通过机械耦合到电极头的导电套管耦合到不可伸展的导体，使得施加到引线主体的向近侧引导的牵引力被不可伸展的导体直接施加到 电极头。
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8.发明授权
公开(公告)号：US6006135A
公开(公告)日：1999-12-21
申请号：US938736
申请日：1997-09-26
申请人： John E. Kast , Andrew J. Ries , Thomas C. Bischoff
发明人： John E. Kast , Andrew J. Ries , Thomas C. Bischoff
CPC分类号： A61N1/3752 , H01R31/06 , H01R2201/12 , Y10S439/909
摘要： A system for connecting electrical leads having connector assemblies carrying electrical connectors to an implantable electrical device having a device housing containing electrical circuitry, including a first connector module fixedly mounted to the device housing, with a first set of electrical connectors coupled to the circuitry within the device housing and a second connector module, with a second set of electrical connectors engageable with the first set of connectors and a second set of connectors electrically coupled to the second set of connectors and engageable with the connectors on the electrical leads and a mechanism for retaining the second module on an outer surface of the device housing adjacent the first module while the second set of connectors engages the first set of connectors. The first and second sets of connectors preferably engage one another as a result of movement of the second module in a first direction into engagement with the second connector module and the retaining mechanism preferably functions to engage and retain the second connector module on the outer surface of the device housing during movement of the second module in the first direction.
摘要翻译： 一种用于连接具有连接器组件的电线的系统，该连接器组件带有电连接器到具有包含电路的装置壳体的可植入电气装置，所述装置壳体包括固定地安装在所述装置壳体上的第一连接器模块，所述第一组电连接器与所述电连接器 设备壳体和第二连接器模块，其具有可与第一组连接器接合的第二组电连接器，以及电耦合到第二组连接器并可与电引线上的连接器接合的第二组连接器，以及用于保持 所述第二模块在所述装置外壳的与所述第一模块相邻的外表面上，而所述第二组连接器接合所述第一组连接器。 第一和第二组连接器优选地由于第二模块在第一方向上的移动而与第二连接器模块接合而相互接合，并且保持机构优选地用于将第二连接器模块接合并保持在第二连接器模块的外表面上 所述装置在第二模块在第一方向移动期间容纳。
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公开(公告)号：US5347708A
公开(公告)日：1994-09-20
申请号：US125093
申请日：1993-09-21
CPC分类号： A61N1/05 , A61N1/056 , H01R11/18 , A61N1/0587 , H01R2201/12 , Y10T29/49071 , Y10T29/49117
摘要： An implantable electrode of the type in which an elongated wire coil forms the electrode surface. The electrode coil is mounted around an insulative lead body and is stabilized on the lead body by means of a plastic filler between the individual turns of the electrode coil, extending radially outwardly to approximately one-third of the diameter of the electrode coil wire. The filler is produced by stretching a portion of the lead body which normally displays an outer diameter greater than the inner diameter of the electrode coil sliding the electrode coil over the lead body, inserting an expandable mandrel into the lead body and expanding the mandrel to urge the lead body into contact with the electrode coil. This assembly is then heated to encourage flow of the lead body into the spaces between the electrode coil to stabilize the coil on electrode body and to present fibrotic ingrowth around the electrode coil wire.
摘要翻译： 一种其中细长的线圈形成电极表面的类型的可植入电极。 电极线圈安装在绝缘引线体的周围，并通过电极线圈的各匝之间的塑料填料在引线体上稳定，径向向外延伸至电极线圈线的直径的大约三分之一。 填充物是通过拉伸一部分引线体而产生的，该部分通常显示的外径大于电极线圈的内径，该电极线圈的内径将电极线圈滑动到引线主体上，将可扩张心轴插入引线本体中并使心轴伸展 引线体与电极线圈接触。 然后将该组件加热以促进引线体流入电极线圈之间的空间中，以使电极体上的线圈稳定并呈现出围绕电极线圈线的纤维向内生长。
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10.发明授权Anchors including rigid bodies defining full length slots for use with implantable medical leads 有权锚固件包括定义全长插槽的刚体，用于可植入医疗引线公开(公告)号：US09517332B2
公开(公告)日：2016-12-13
申请号：US13357975
申请日：2012-01-25
CPC分类号： A61N1/05 , A61M2025/0293 , A61N1/0558 , A61N1/057 , A61N2001/0582 , H01R43/20
摘要： Anchors for use with implantable medical leads include an elastic body containing one or more rigid bodies that have longitudinal free edges. The longitudinal free edges run from end to end to define full length slots. Partial length slots may also be included within the one or more rigid bodies. The full length and partial length slots allow for deflection of the rigid bodies against the body of an implantable medical lead to hold the anchor in place on the lead. The full length slots allow a blade to pass through and cut a slit in the elastic body which allows the anchor to be removed from the lead.
摘要翻译： 与可植入医疗引线一起使用的锚杆包括弹性体，其包含具有纵向自由边缘的一个或多个刚体。 纵向自由边缘从一端到另一端延伸以限定全长缝隙。 部分长度的狭槽也可以包括在一个或多个刚体内。 全长度和部分长度狭槽允许刚体抵靠可植入医疗引线的主体的偏转，以将锚固定在导线上的适当位置。 全长缝隙允许刀片通过并切割弹性体中的狭缝，这允许锚固体从铅离开。
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