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1.发明授权
公开(公告)号：US5662708A
公开(公告)日：1997-09-02
申请号：US512584
申请日：1995-08-08
摘要： A rheologically modified, osmotically balanced dispersion for an implant for the body. The dispersion includes an osmotic control agent of preferably polyvinylpyrrolidinone, a rheological agent of preferably guar gum, and an antimicrobial. Methods for filling an implant are also disclosed. The osmotic control agent or first polymeric osmotic control agent is present in the dispersion in an amount effective to substantially balance the osmotic pressure of the implant with the osmotic pressure of the portion of the body into which it is implanted. The rheological agent or second polymeric agent forms a three-dimensional network and is present in the dispersion in an amount effective such that the fill material is pseudoplastic. Both the first and second polymeric agents are biocompatible.
摘要翻译： 用于人体植入物的流变改性，渗透平衡的分散体。 分散体包括优选聚乙烯吡咯烷酮的渗透控制剂，优选瓜耳胶的流变剂和抗微生物剂。 还公开了用于填充植入物的方法。 渗透控制剂或第一聚合渗透控制剂以有效基本上平衡植入物的渗透压与植入物的部分的渗透压的量存在于分散体中。 流变剂或第二聚合物形成三维网络并且以有效的量存在于分散体中，使得填充材料是假塑性的。 第一和第二聚合物都是生物相容的。
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2.发明授权
公开(公告)号：US5997574A
公开(公告)日：1999-12-07
申请号：US924457
申请日：1997-08-29
摘要： A rheologically modified, osmotically balanced dispersion for an implant for the body. The dispersion includes an osmotic control agent of preferably polyvinylpyrrolidinone, a rheological agent of preferably guar gum, and an antimicrobial. Methods for filling an implant are also disclosed. The osmotic control agent or first polymeric agent is present in the dispersion in an amount effective to substantially balance the osmotic pressure of the implant with the osmotic pressure of the portion of the body into which it is implanted. The rheological agent or second polymeric agent forms a three-dimensional network and is present in the dispersion in an amount effective such that the fill material is pseudoplastic. Both the first and second polymeric agents are biocompatible.
摘要翻译： 用于人体植入物的流变改性，渗透平衡的分散体。 分散体包括优选聚乙烯吡咯烷酮的渗透控制剂，优选瓜耳胶的流变剂和抗微生物剂。 还公开了用于填充植入物的方法。 渗透控制剂或第一聚合物以分散体的形式存在，其量可以有效地将植入物的渗透压与植入物的部分的渗透压进行平衡。 流变剂或第二聚合物形成三维网络并且以有效的量存在于分散体中，使得填充材料是假塑性的。 第一和第二聚合物都是生物相容的。
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3.发明授权
公开(公告)号：US5630844A
公开(公告)日：1997-05-20
申请号：US473284
申请日：1995-06-07
CPC分类号： B32B25/00 , A61F2/12 , A61L27/16 , A61L27/20 , A61L27/34 , A61L29/041 , A61L29/043 , A61L29/085 , A61F2210/0071 , A61F2240/001 , B29C41/14
摘要： A biocompatible hydrophobic laminate. The laminate structure includes one layer of a rubber, such as silicone rubber, which is biocompatible with the inside of the body. The laminate structure further includes a hydrophobic layer or membrane formed of a thermoplastic elastomer such as a styrene triblock copolymer. The triblock copolymer may contain styrene endblocks with an elastomeric midblock such as polyisoprene, polybutadiene, polyisobutylene, and poly(ethylene-co-butylene). The laminate structure may be utilized for structures to be introduced into the body, such as for a breast prosthesis shell or a coating for a catheter.
摘要翻译： 生物相容的疏水层压板。 层压结构包括一层橡胶，例如硅橡胶，其与身体的内部生物相容。 层压结构还包括由热塑性弹性体如苯乙烯三嵌段共聚物形成的疏水层或膜。 三嵌段共聚物可以含有具有弹性体中间嵌段的苯乙烯端嵌段，例如聚异戊二烯，聚丁二烯，聚异丁烯和聚（乙烯 - 共 - 丁烯）。 层压结构可用于被引入体内的结构，例如用于乳房假体外壳或用于导管的涂层。
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公开(公告)号：US07105116B2
公开(公告)日：2006-09-12
申请号：US10462278
申请日：2003-06-16
CPC分类号： A61F2/12 , A61F2/0077 , B29C37/0053 , B29C41/14 , B29C2791/001 , B29L2031/7532
摘要： A non-rotating anatomical-shaped breast implant having a front side with a smooth surface and a rear side with a textured surface. A smooth surface ripples or wrinkles little, if at all. Rippling or wrinkling of the implant may undesirably produce a visible or palpable waviness on the skin of the breast. A smooth surface is more likely to produce the look and feel of a natural breast. A rear side with a textured surface is desirable because tissue growth of the body, after the implant has been implanted, engages the textured surface to anchor the implant in place such that the front side with the smooth surface remains matched with the front side of the body and such that the anatomical-shaped breast implant with its tear drop shaped fullness remains at a natural position within the breast. The disclosure further includes a method for minimizing the rotation of an implant within the body and a method for making an implant envelope that has different thicknesses.
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公开(公告)号：US06692527B1
公开(公告)日：2004-02-17
申请号：US09452656
申请日：1999-12-01
IPC分类号： A61F212
CPC分类号： A61F2/12 , A61F2/0077 , B29C37/0053 , B29C41/14 , B29C2791/001 , B29L2031/7532
摘要： A non-rotating anatomical-shaped breast implant having a front side with a smooth surface and a rear side with a textured surface. A smooth surface ripples or wrinkles little, if at all. Rippling or wrinkling of the implant may undesirably produce a visible or palpable waviness on the skin of the breast. A smooth surface is more likely to produce the look and feel of a natural breast. A rear side with a textured surface is desirable because tissue growth of the body, after the implant has been implanted, engages the textured surface to anchor the implant in place such that the front side with the smooth surface remains matched with the front side of the body and such that the anatomical-shaped breast implant with its tear drop shaped fullness remains at a natural position within the breast. The disclosure further includes a method for minimizing the rotation of an implant within the body and a method for making an implant envelope that has different thicknesses.
摘要翻译： 一种非旋转解剖形状的乳房植入物，其具有光滑表面的前侧和具有纹理表面的后侧。 如果有的话，光滑的表面波纹或皱纹很小。 植入物的起皱或皱纹可能不期望地在乳房的皮肤上产生可见或明显的波纹。 平滑的表面更有可能产生自然乳房的外观和感觉。 具有纹理表面的后侧是理想的，因为在植入物植入之后，身体的组织生长与纹理化表面接合以将植入物锚定就位，使得具有光滑表面的前侧保持与 使得具有其泪滴形状丰满的解剖形状的乳房植入物保持在乳房内的自然位置。 本公开还包括一种用于最小化体内植入物的旋转的方法，以及用于制造具有不同厚度的植入物外壳的方法。
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6.发明授权
公开(公告)号：US6162251A
公开(公告)日：2000-12-19
申请号：US318036
申请日：1999-05-25
申请人： Kenneth C. Kredovski
发明人： Kenneth C. Kredovski
IPC分类号： A61F2/02
CPC分类号： A61F2/02
摘要： An implant that includes an envelope, a saline based fill material in the envelope, and a single valve. The envelope is formed by a mandrel dipping process and includes an opening formed by a support rod for the mandrel. To remove the envelope from the mandrel, the opening is stretched over the mandrel. This opening, a natural port, is sealed by a single valve structure. The valve structure includes the valve through which the saline based fill material is introduced. The valve is two piece, and the two pieces mechanically interlock to bias and draw a diaphragm tightly against a valve seat, which provides a primary resilient closure for the valve. The valve further includes a secondary resilient closure where two confronting faces form a slit through which a filling tube is inserted and where end portions of the two confronting faces are bonded to each other to minimize the chances of the slit tearing at its ends.
摘要翻译： 植入物，其包括封套，封套中的盐水填充材料和单个阀。 信封由芯棒浸渍工艺形成，并且包括由用于心轴的支撑杆形成的开口。 为了从心轴移除信封，将开口在心轴上拉伸。 这个开口，一个天然的港口，被一个单一的阀门结构密封。 阀结构包括引入盐水填充材料的阀。 阀门是两件式，两件机械互锁以偏置隔膜并将隔膜紧紧地压在阀座上，这为阀门提供了主要的弹性闭合。 阀还包括辅助弹性闭合件，其中两个相对的面形成狭缝，填充管通过该狭缝插入，并且两个相对面的端部彼此结合以最小化在其端部处的狭缝撕裂的机会。
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