公开(公告)号：US07141683B2

公开(公告)日：2006-11-28

申请号：US10428607

申请日：2003-05-02

申请人： Thomas Haas ,  Georg Thiele ,  Gerald Moroff ,  Norbert Ullrich ,  Willi Hofen ,  Guido Stochniol ,  Hubertus Eickhoff ,  Werner Pohl ,  Wolfgang Wöll ,  Claudia Brasse ,  José Berges ,  Percy Kampeis

发明人： Thomas Haas ,  Georg Thiele ,  Gerald Moroff ,  Norbert Ullrich ,  Willi Hofen ,  Guido Stochniol ,  Hubertus Eickhoff ,  Werner Pohl ,  Wolfgang Wöll ,  Claudia Brasse ,  José Berges ,  Percy Kampeis

IPC分类号： C07D301/12

CPC分类号： C07D301/12

摘要： A process for the epoxidation of olefins which includes i) reacting an olefin with hydrogen peroxide in presence of an epoxidation catalyst and an alcoholic solvent; ii) separating product olefin oxide and unreacted olefin from the reaction product of step i); iii) recovering a stream comprising the alcoholic solvent; and iv) subjecting the recovered stream of step iii) to hydrogenation.

摘要翻译： 烯烃环氧化方法，其包括：i）在环氧化催化剂和醇溶剂的存在下使烯烃与过氧化氢反应; ii）从步骤i）的反应产物中分离产物烯烃氧化物和未反应的烯烃; iii）回收包含醇溶剂的料流; 和iv）使回收的步骤iii）的流经受氢化。

公开(公告)号：US06878836B2

公开(公告)日：2005-04-12

申请号：US10839572

申请日：2004-05-05

申请人： Thomas Haas ,  Claudia Brasse ,  Wolfgang Wöll ,  Willi Hofen ,  Bernd Jaeger ,  Guido Stochniol ,  Norbert Ullrich

发明人： Thomas Haas ,  Claudia Brasse ,  Wolfgang Wöll ,  Willi Hofen ,  Bernd Jaeger ,  Guido Stochniol ,  Norbert Ullrich

IPC分类号： C07D301/12 ,  C07D303/04

CPC分类号： C07D303/04 ,  C07D301/12 ,  Y02P20/584

摘要： A process for the continuous epoxidation of propene with hydrogen peroxide in the presence of a titanium silicalite catalyst and a methanol solvent, wherein the catalyst is periodically regenerated by washing with a methanol solvent at a temperature of at least 100° C. and the epoxidation reaction is carried out for periods of more than 300 h between two regeneration steps.

摘要翻译： 一种在钛硅沸石催化剂和甲醇溶剂存在下用过氧化氢连续环氧化丙烯的方法，其中催化剂通过在至少100℃的温度下用甲醇溶剂洗涤并周期性地再生，并且环氧化反应 在两个再生步骤之间进行超过300小时的时间。

公开(公告)号：US07169945B2

公开(公告)日：2007-01-30

申请号：US10724300

申请日：2003-11-26

申请人： Thomas Haas ,  Willi Hofen ,  Wolfgang Wöll ,  Claudia Brasse ,  Guido Stochniol ,  Norbert Ullrich

发明人： Thomas Haas ,  Willi Hofen ,  Wolfgang Wöll ,  Claudia Brasse ,  Guido Stochniol ,  Norbert Ullrich

IPC分类号： C07D301/12

CPC分类号： C07D301/12 ,  Y02P20/584

摘要： A process for the catalytic epoxidation of olefins in the presence of a titanium containing zeolite catalyst and a polar solvent whereby the deactivation of the catalyst upon recycling of the solvent has been considerably reduced. In the process one or more nitrogen containing compounds are introduced at some stage, a solvent stream is recovered, treated to contain less than 50 wppm nitrogen in the form of organic nitrogen compounds and at least a part of it is recycled to the epoxidation step. Also disclosed is a process for the catalytic epoxidation of propene which integrates the treatment and recycle of the solvent into the workup of the reaction mixture.

摘要翻译： 一种在含钛沸石催化剂和极性溶剂的存在下烯烃的催化环氧化方法，从而显着减少了在溶剂再循环时催化剂失活。 在该过程中，在一些阶段引入一种或多种含氮化合物，回收溶剂流，将其处理为含有少于50wppm氮的有机氮化合物形式，并将其至少一部分再循环至环氧化步骤。 还公开了丙烯的催化环氧化方法，其将溶剂的处理和再循环整合到反应混合物的后处理中。

公开(公告)号：US06838572B2

公开(公告)日：2005-01-04

申请号：US10669993

申请日：2003-09-24

申请人： Thomas Haas ,  Claudia Brasse ,  Guido Stochniol ,  Willi Hofen ,  Wolfgang Wöll ,  Georg Thiele

发明人： Thomas Haas ,  Claudia Brasse ,  Guido Stochniol ,  Willi Hofen ,  Wolfgang Wöll ,  Georg Thiele

IPC分类号： C01B15/013 ,  C01B15/023 ,  C07D301/12

CPC分类号： C01B15/013 ,  C01B15/023 ,  C07D301/12

摘要： A continuous process for the epoxidation of olefins with hydrogen peroxide in the presence of a heterogeneous catalyst promoting the epoxidation reaction, whereby the aqueous reaction mixture contains i) an olefin; ii) hydrogen peroxide; iii) less than 100 wppm of alkali metals, earth alkali metals, both irrespective whether in ionic, complex or covalently bonded form, bases or cations of bases having a pkB of less than 4.5, or combinations thereof; and, iv) at least 100 wppm of bases or cations of bases having a pkB of at least 4.5 or combinations thereof, whereby the wppm are based on the total weight of hydrogen peroxide in the reaction mixture.

摘要翻译： 在促进环氧化反应的多相催化剂的存在下用过氧化氢环氧化烯烃的连续方法，由此含水反应混合物含有i）烯烃; ii）过氧化氢; iii）小于100wppm的碱金属，碱土金属，无论是在离子，复合或共价键合的形式，碱性或pKB小于4.5的碱的阳离子，或其组合; 和iv）至少100wppm的pkB至少为4.5的碱或碱的阳离子或其组合，其中wppm是基于反应混合物中过氧化氢的总重量。

公开(公告)号：US07091384B2

公开(公告)日：2006-08-15

申请号：US10516319

申请日：2003-06-25

申请人： Bernd Jaeger ,  Thomas Haas ,  Guido Stochniol ,  Christian Lettmann ,  Willi Hofen ,  Klaus Stadtmueller ,  Joerg Lotz

发明人： Bernd Jaeger ,  Thomas Haas ,  Guido Stochniol ,  Christian Lettmann ,  Willi Hofen ,  Klaus Stadtmueller ,  Joerg Lotz

IPC分类号： C07C209/72

CPC分类号： C07C209/72 ,  C07C211/36

摘要： The invention relates to a process for increasing the selectivity of the hydrogenation of 4,4′-diaminodiphenylmethane (4,4′-MDA) to diaminodicyclohexylmethane (4,4′-HMDA) by catalytic hydrogenation of a mixture containing 4,4′-MDA as the main component and its mono-N-methyl derivative as a secondary component. According to the invention, the hydrogenation is terminated before a conversion of 4,4′-MDA to 4,4′-HMDA of 99% is achieved. Under these conditions, a substantially smaller proportion of the N-methyl-4,4′-MDA is hydrogenated to N-methyl-4,4-HMDA.

摘要翻译： 本发明涉及通过催化氢化含有4,4'-二氨基二苯基甲烷（4,4'-MDA）的混合物的方法提高4,4'-二氨基二苯基甲烷（4,4'-MDA） MDA为主要成分，其单-N-甲基衍生物为次要成分。 根据本发明，在将4,4'-MDA转化为99％的4,4'-HMDA之前终止氢化。 在这些条件下，将大部分比例的N-甲基-4,4'-MDA氢化成N-甲基-4,4-HMDA。

公开(公告)号：US20050148797A1

公开(公告)日：2005-07-07

申请号：US10516319

申请日：2003-06-25

申请人： Bernd Jaeger ,  Thomas Haas ,  Guido Stochniol ,  Christian Lettmann ,  Willi Hofen ,  Klaus Stadtmuller ,  Jorg Lotz

发明人： Bernd Jaeger ,  Thomas Haas ,  Guido Stochniol ,  Christian Lettmann ,  Willi Hofen ,  Klaus Stadtmuller ,  Jorg Lotz

IPC分类号： C07B61/00 ,  C07C209/72 ,  C07C211/36 ,  C07C29/72

CPC分类号： C07C209/72 ,  C07C211/36

摘要： The invention relates to a process for increasing the selectivity of the hydrogenation of 4,4′-diaminodiphenylmethane (4,4′-MDA) to diaminodicyclohexylmethane (4,4′-HMDA) by catalytic hydrogenation of a mixture containing 4,4′-MDA as the main component and its mono-N-methyl derivative as a secondary component. According to the invention, the hydrogenation is terminated before a conversion of 4,4′-MDA to 4,4′-HMDA of 99% is achieved. Under these conditions, a substantially smaller proportion of the N-methyl-4,4′-MDA is hydrogenated to N-methyl-4,4-HMDA.

摘要翻译： 本发明涉及通过催化氢化含有4,4'-二氨基二苯基甲烷（4,4'-MDA）的混合物的方法提高4,4'-二氨基二苯基甲烷（4,4'-MDA） MDA为主要成分，其单-N-甲基衍生物为次要成分。 根据本发明，在将4,4'-MDA转化为99％的4,4'-HMDA之前终止氢化。 在这些条件下，将大部分比例的N-甲基-4,4'-MDA氢化成N-甲基-4,4-HMDA。

公开(公告)号：US07049450B2

公开(公告)日：2006-05-23

申请号：US10723270

申请日：2003-11-26

申请人： Willi Hofen ,  Thomas Haas ,  Wolfgang Wöll ,  Georg Thiele

发明人： Willi Hofen ,  Thomas Haas ,  Wolfgang Wöll ,  Georg Thiele

IPC分类号： C07D301/03 ,  C07D301/12 ,  B01D3/34

CPC分类号： C07D301/32

摘要： A process for the purification of a crude propene oxide containing methanol and acetaldehyde by a continuously operated extractive distillation using an extraction solvent lowering the volatility of methanol and feeding a compound containing an unsubstituted NH2 group capable of reacting with acetaldehyde to a distillation column at a point above the feeding point of the crude propene oxide to give a purified propene oxide containing less than 100 ppm methanol and less than 100 ppm acetaldehyde. There is also disclosed a process for the catalytic epoxidation of propene that includes this purification stage.

摘要翻译： 一种通过连续操作的萃取蒸馏来纯化含有甲醇和乙醛的粗丙烯氧化物的方法，该提取溶剂使用降低甲醇挥发性的萃取溶剂，并将含有能与下列物质反应的未取代的NH 2基团的化合物 乙醛在粗丙烯氧化物的进料点上方的蒸馏塔中，得到含有小于100ppm甲醇和小于100ppm乙醛的纯化丙烯氧化物。 还公开了包括该纯化阶段的丙烯的催化环氧化方法。

公开(公告)号：US06596883B2

公开(公告)日：2003-07-22

申请号：US10226766

申请日：2002-08-23

申请人： Willi Hofen ,  Thomas Haas ,  Wolfgang Wöll ,  Georg Thiele

发明人： Willi Hofen ,  Thomas Haas ,  Wolfgang Wöll ,  Georg Thiele

IPC分类号： C07D30132

CPC分类号： C07D301/12

摘要： A process for the working up of a product stream from the epoxidation of olefins that contains olefin, olefin oxide, water-miscible organic solvent and water, by separating this product stream into an overhead product containing olefin, olefin oxide and organic solvent, and into a bottom product containing organic solvent and water, wherein the separation takes place in a pre-evaporator with less than 10 theoretical separation stages at a pressure of 1.5 to less than 3 bar, and 20 to 60% of the total amount of organic solvent introduced with the product stream is removed with the overhead product and the balance remains in the bottom product. A process for the epoxidation of olefins that includes this working up stage is also disclosed.

公开(公告)号：US06720436B2

公开(公告)日：2004-04-13

申请号：US10384217

申请日：2003-03-07

申请人： Willi Hofen ,  Georg Thiele ,  Thomas Haas ,  Wolfgang Wöll ,  Percy Kampeis ,  Bärbel Kolbe

发明人： Willi Hofen ,  Georg Thiele ,  Thomas Haas ,  Wolfgang Wöll ,  Percy Kampeis ,  Bärbel Kolbe

IPC分类号： C07D30112

CPC分类号： C07D301/12

摘要： A process for the catalytic epoxidation of olefins in at least one reaction stage comprising: (a) reacting the olefin with hydrogen peroxide in an organic, water-miscible solvent in the presence of a titanium silicalite catalyst in a reactor while continuously feeding an inert gas stream into the reactor, (b) continuously removing an exit gas stream containing olefin oxide, unreacted olefin, oxygen and inert gas from the reactor, (c) bringing the exit gas stream into contact in an absorption unit with the same solvent as used in the reaction stage, (d) removing a solvent stream loaded with olefin and olefin oxide from the absorption unit and (e) discharging an gas stream containing oxygen and the inert gas from the absorption unit.

摘要翻译： 一种用于在至少一个反应阶段中对烯烃进行催化环氧化的方法，包括：（a）在反应器中在钛硅沸石催化剂存在下，使烯烃与有机的水混溶性溶剂中的过氧化氢反应，同时连续进料惰性气体 （b）从反应器中连续除去含有烯烃氧化物，未反应的烯烃，氧和惰性气体的出口气流，（c）使出口气流与吸收单元中的相同溶剂接触， 反应阶段，（d）从吸收单元除去负载有烯烃和烯烃氧化物的溶剂流，和（e）从吸收单元排出含有氧和惰性气体的气流。

公开(公告)号：US08481765B2

公开(公告)日：2013-07-09

申请号：US12919637

申请日：2008-12-16

申请人： Willi Hofen ,  Claudia Brasse ,  Robert Franke ,  Robert Katzer

发明人： Willi Hofen ,  Claudia Brasse ,  Robert Franke ,  Robert Katzer

IPC分类号： C07D301/12 ,  C07D301/06

CPC分类号： C07D301/12 ,  Y02P20/127

摘要： The invention relates to a method for the production of epichlorohydrin, wherein a chloropropane-containing ally chloride in excess is reacted in a first reaction stage with hydrogen peroxide. The non-reacted ally chloride is separated and returned to the reaction, wherein part of the separated ally chloride is added to a second reaction stage and reacted with hydrogen peroxide, wherein the hydrogen peroxide quantity is selected in the second reaction stage such that the ally chloride is largely reacted. The chloropropanes are separated from the reaction mixture of the second reaction stage by means of distillation and removed from the process.

摘要翻译： 本发明涉及一种制备表氯醇的方法，其中过量的含氯丙烷的烯丙基氯在第一反应阶段与过氧化氢反应。 将未反应的烯丙基氯分离并返回反应，其中将部分分离的烯丙基氯加入到第二反应阶段中，并与过氧化氢反应，其中在第二反应阶段选择过氧化氢的量， 氯化物大部分反应。 通过蒸馏将氯丙烷与第二反应阶段的反应混合物分离，并从该方法中除去。