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公开(公告)号:US10005836B2
公开(公告)日:2018-06-26
申请号:US14940961
申请日:2015-11-13
申请人: Tinya Abrams , Steven Bruce Cohen , Jason Damiano , Clemens Dürr , Thomas Huber , Daniel Menezes , Kathy Miller , Katherine Rendahl , Jean-Michel Rene Rondeau
发明人: Tinya Abrams , Steven Bruce Cohen , Jason Damiano , Clemens Dürr , Thomas Huber , Daniel Menezes , Kathy Miller , Katherine Rendahl , Jean-Michel Rene Rondeau
IPC分类号: C07K16/28 , A61K47/68 , C07K16/30 , A61K31/53 , A61K31/5365 , G01N33/574
CPC分类号: C07K16/28 , A61K31/5365 , A61K47/6803 , A61K47/6849 , A61K47/6851 , C07K16/30 , C07K2299/00 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/51 , C07K2317/515 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/622 , C07K2317/73 , C07K2317/732 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2319/00 , G01N33/57492 , G01N2333/705
摘要: This application discloses anti-P-cadherin antibodies, antigen binding fragments thereof, and antibody drug conjugates of said antibodies or antigen binding fragments. The invention also relates to methods of treating cancer using the antibodies, antigen binding fragments, and antibody drug conjugates. Also disclosed herein are methods of making the antibodies, antigen binding fragments, and antibody drug conjugates, and methods of using the antibodies and antigen binding fragments as diagnostic reagents.
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公开(公告)号:US20190119375A1
公开(公告)日:2019-04-25
申请号:US15988659
申请日:2018-05-24
申请人: Tinya Abrams , Steven Bruce Cohen , Jason Damiano , Clemens Dürr , Thomas Huber , Daniel Menezes , Kathy Miller , Katherine Rendahl , Jean-Michel Rene Rondeau
发明人: Tinya Abrams , Steven Bruce Cohen , Jason Damiano , Clemens Dürr , Thomas Huber , Daniel Menezes , Kathy Miller , Katherine Rendahl , Jean-Michel Rene Rondeau
IPC分类号: C07K16/28 , A61K47/68 , C07K16/30 , A61K31/5365 , G01N33/574
摘要: This application discloses anti-P-cadherin antibodies, antigen binding fragments thereof, and antibody drug conjugates of said antibodies or antigen binding fragments. The invention also relates to methods of treating cancer using the antibodies, antigen binding fragments, and antibody drug conjugates. Also disclosed herein are methods of making the antibodies, antigen binding fragments, and antibody drug conjugates, and methods of using the antibodies and antigen binding fragments as diagnostic reagents.
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公开(公告)号:US20160137730A1
公开(公告)日:2016-05-19
申请号:US14940961
申请日:2015-11-13
申请人: Tinya ABRAMS , Steven Bruce Cohen , Jason Damiano , Clemens Dürr , Thomas Huber , Daniel Menezes , Kathy Miller , Katherine Rendahl , Jean-Michel Rene Rondeau
发明人: Tinya ABRAMS , Steven Bruce Cohen , Jason Damiano , Clemens Dürr , Thomas Huber , Daniel Menezes , Kathy Miller , Katherine Rendahl , Jean-Michel Rene Rondeau
IPC分类号: C07K16/28 , G01N33/574 , A61K47/48 , C07K16/30 , A61K31/5365
CPC分类号: C07K16/28 , A61K31/5365 , A61K47/6803 , A61K47/6849 , A61K47/6851 , C07K16/30 , C07K2299/00 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/51 , C07K2317/515 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/622 , C07K2317/73 , C07K2317/732 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2319/00 , G01N33/57492 , G01N2333/705
摘要: This application discloses anti-P-cadherin antibodies, antigen binding fragments thereof, and antibody drug conjugates of said antibodies or antigen binding fragments. The invention also relates to methods of treating cancer using the antibodies, antigen binding fragments, and antibody drug conjugates. Also disclosed herein are methods of making the antibodies, antigen binding fragments, and antibody drug conjugates, and methods of using the antibodies and antigen binding fragments as diagnostic reagents.
摘要翻译: 本申请公开了抗P-钙粘蛋白抗体,其抗原结合片段和所述抗体或抗原结合片段的抗体药物偶联物。 本发明还涉及使用抗体,抗原结合片段和抗体药物缀合物治疗癌症的方法。 本文还公开了制备抗体,抗原结合片段和抗体药物缀合物的方法,以及使用抗体和抗原结合片段作为诊断试剂的方法。
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公开(公告)号:US09982045B2
公开(公告)日:2018-05-29
申请号:US14820897
申请日:2015-08-07
申请人: Carl Uli Bialucha , Scott Collins , Clemens Dürr , Tiancen Hu , Mary Jo Janatpour , Matthew John Meyer
发明人: Carl Uli Bialucha , Scott Collins , Clemens Dürr , Tiancen Hu , Mary Jo Janatpour , Matthew John Meyer
IPC分类号: A61K47/48 , C07K16/28 , G01N33/574 , A61K45/06 , A61K31/4738 , A61K47/68 , A61K39/00
CPC分类号: C07K16/28 , A61K31/4738 , A61K45/06 , A61K47/6803 , A61K47/6849 , A61K47/6889 , A61K2039/505 , C07K2317/21 , C07K2317/34 , C07K2317/40 , C07K2317/55 , C07K2317/56 , C07K2317/73 , C07K2317/92 , G01N33/57492 , G01N2333/705 , A61K2300/00 , A61K39/395
摘要: The present invention relates to anti-CDH6 antibodies, antibody fragments, antibody drug conjugates, and their uses for the treatment of cancer.
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公开(公告)号:US10238748B2
公开(公告)日:2019-03-26
申请号:US15502478
申请日:2015-08-07
申请人: Carl Uli Bialucha , Scott Collins , Clemens Dürr , Tiancen Hu , Mary Jo Janatpour , Matthew John Meyer
发明人: Carl Uli Bialucha , Scott Collins , Clemens Dürr , Tiancen Hu , Mary Jo Janatpour , Matthew John Meyer
IPC分类号: A61K39/395 , A61K47/48 , C07K16/28 , A61K31/537 , A61K31/635 , A61K31/428 , A61K38/05 , A61K31/519 , C07K16/30
摘要: The present invention relates to anti-CDH6 antibodies, antibody fragments, antibody drug conjugates, and their uses for the treatment of cancer.
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