利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

37 条记录 (耗时 0.029 秒)

    Mitomycin derivatives as antileukemia agents
    1.
    发明授权
    Mitomycin derivatives as antileukemia agents 失效
    丝裂霉素衍生物作为抗白血病剂

    公开(公告)号：US4791113A

    公开(公告)日：1988-12-13

    申请号：US57889

    申请日：1987-05-12

    申请人： Tokuyuki Kuroda ,  Koji Hisamura ,  Tohru Sugaya ,  Yutaka Ohsawa ,  Hideo Ueno ,  Makoto Morimoto ,  Tadashi Ashizawa

    发明人： Tokuyuki Kuroda ,  Koji Hisamura ,  Tohru Sugaya ,  Yutaka Ohsawa ,  Hideo Ueno ,  Makoto Morimoto ,  Tadashi Ashizawa

    IPC分类号： C07D487/14 ,  A61K31/505 ,  A61K31/40 ,  C07D487/04

    CPC分类号： C07D487/14

    摘要： Mitomycin derivatives having potent antitumor activity having the formula: ##STR1## wherein A is ON--or R.sub.4 N.dbd.N--[wherein R.sub.4 is selected from ##STR2## and optionally substituted heterocyclic groups (wherein R.sub.5 and R.sub.8 are each independently selected from hydrogen, lower alkyl and lower cycloalkyl; R.sub.6 is selected from hydrogen, halogen, hydroxy, lower alkoxy, amino and nitro; R.sub.7 is selected from lower alkyl and lower cycloalkyl; and X is selected from oxygen, sulphur and imino)];R.sub.1 and R.sub.2 are each independently selected from hydrogen, lower alkyl, lower cycloalkyl, optionally substituted aralkyl, optionally substituted alkanoyl, optionally substituted arylcarbonyl, optionally substituted alkanesulfonyl, arylsulfonyl and aralkylsulfonyl;R.sub.3 is hydrogen or carbamoyl;Y is hydrogen or methyl;Z is selected from hydrogen, methyl and acetyl;and is an .alpha. or .beta. bond.

    摘要翻译： 丝裂霉素衍生物具有有效的抗肿瘤活性，具有下式：其中A为ON-或R 4 N = N- [其中R 4为选自下列任意取代的杂环基团（其中R5和R8 各自独立地选自氢，低级烷基和低级环烷基; R6选自氢，卤素，羟基，低级烷氧基，氨基和硝基; R7选自低级烷基和低级环烷基; X选自氧，硫和亚氨基 ）]; R 1和R 2各自独立地选自氢，低级烷基，低级环烷基，任选取代的芳烷基，任选取代的烷酰基，任选取代的芳基羰基，任选取代的烷基磺酰基，芳基磺酰基和芳烷基磺酰基; R3是氢或氨基甲酰基; Y是氢或甲基; Z选自氢，甲基和乙酰基; 并且是α或β键。

    Remote control, auto-focus camera system
    4.
    发明授权
    Remote control, auto-focus camera system 失效
    遥控器，自动对焦摄像系统

    公开(公告)号：US06351605B1

    公开(公告)日：2002-02-26

    申请号：US09604928

    申请日：2000-06-28

    申请人： Mikio Ogi ,  Yutaka Ohsawa

    发明人： Mikio Ogi ,  Yutaka Ohsawa

    IPC分类号： G03B1700

    CPC分类号： G03B17/38

    摘要： A remote control auto-focus camera system includes a camera body; a transmitter provided separately from the camera body, wherein the transmitter transmits a remote control signal; a focusing device, a photometering device and an exposure device, provided in the camera body; a photographing operation member, provided on the camera body, which is adapted to operate both the photometering device and the focusing device upon a first operation thereof and to operate the exposure device upon a second operation thereof; and a controller adapted to operate the photometering device and the exposure device in this order without operating the focusing device upon receipt of the remote control signal transmitted.

    摘要翻译： 遥控自动对焦照相机系统包括相机主体; 与所述照相机主体分开设置的发射器，其中所述发射器发射遥控信号; 设置在照相机主体中的聚焦装置，测光装置和曝光装置; 设置在所述照相机主体上的拍摄操作构件，其适于在其第一操作时同时操作所述测光装置和所述聚焦装置，并且在其第二操作时操作所述曝光装置; 以及控制器，其适于在接收到所发送的遥控信号的情况下按顺序操作测光装置和曝光装置，而不操作聚焦装置。

    Data communication method between circuits
    5.
    发明授权
    Data communication method between circuits 失效
    电路之间的数据通信方法

    公开(公告)号：US5283663A

    公开(公告)日：1994-02-01

    申请号：US568516

    申请日：1990-08-16

    申请人： Masahiro Kawasaki ,  Teruhiko Naruo ,  Yutaka Ohsawa ,  Isamu Hashimoto

    发明人： Masahiro Kawasaki ,  Teruhiko Naruo ,  Yutaka Ohsawa ,  Isamu Hashimoto

    IPC分类号： G08C19/28 ,  H04L25/48 ,  H04N1/41

    CPC分类号： G08C19/28

    摘要： A method is disclosed for performing data communication between a pair of circuits. The data communication is established by serially transmitting information which includes pulse signals. In executing the method, a reference time is determined as an instant of a first level change in a first direction of a pulse signal output from one of the circuits to the other. A judgement is made as to whether a first bit of data is a "1" or a "0" in accordance with a time period extending from the reference time to an instant of a subsequent level change in the first direction following the reference time. The instant of the subsequent level change in the first direction is determined as a reference time relative to the next bit of data in the pulse signal. The data of a predetermined number of bits is continuously transmitted by repeatedly establishing reference times and judging the value of a bit based on the time period which extends from the reference time to a subsequent level change.

    摘要翻译： 公开了一种用于在一对电路之间执行数据通信的方法。 通过串行发送包括脉冲信号的信息建立数据通信。 在执行该方法时，将参考时间确定为从一个电路输出到另一个的脉冲信号的第一方向上的第一电平变化的时刻。 根据在参考时间之后的第一方向上从参考时间到后续电平变化的时刻的时间段，判断数据的第一位是“1”还是“0”。 将第一方向上随后的电平变化的时刻确定为相对于脉冲信号中的下一位数据的参考时间。 通过重复地建立参考时间并且基于从参考时间延伸到随后的电平改变的时间段来判断比特的值来连续地发送预定数量的比特的数据。

    Stop-down signal adjusting circuit in automatic aperture control camera
    6.
    发明授权
    Stop-down signal adjusting circuit in automatic aperture control camera 失效
    自动光圈控制摄像机中的停止信号调节电路

    公开(公告)号：US4831400A

    公开(公告)日：1989-05-16

    申请号：US77462

    申请日：1987-07-24

    申请人： Satoshi Takami ,  Yutaka Ohsawa

    发明人： Satoshi Takami ,  Yutaka Ohsawa

    IPC分类号： G03B7/095 ,  G03B7/085 ,  G03B9/07 ,  H03G3/20

    CPC分类号： H03G3/30 ,  G03B7/085

    摘要： The oscillation wave signal generated during lens stop-down is amplified by an adjustable gain amplifier the gain of which is controlled in accordance with the peak value of the oscillation wave signal detected during a predetermined time period, to thereby maintain a substantially constant oscillation wave signal amplitude during lens stop-down.

    摘要翻译： 在透镜停止期间产生的振荡波信号由可调节增益放大器放大，其增益根据在预定时间段内检测到的振荡波信号的峰值来控制，从而保持基本恒定的振荡波信号 镜头停止时的幅度。

    Photo-electric conversion circuit
    7.
    发明授权
    Photo-electric conversion circuit 失效
    光电转换电路

    公开(公告)号：US4806748A

    公开(公告)日：1989-02-21

    申请号：US65436

    申请日：1987-06-23

    申请人： Satoshi Takami ,  Yutaka Ohsawa

    发明人： Satoshi Takami ,  Yutaka Ohsawa

    IPC分类号： G01J1/44 ,  G03B7/081 ,  H03F3/08 ,  H03F3/45

    CPC分类号： G01J1/44 ,  H03F3/082 ,  G01J2001/446

    摘要： A photoelectric amplifier comprising a photodiode having an anode connected to a gate of a first FET and a cathode connected to a gate of a second FET, with the second FET having a source-gate interconnection so as to be self-biasing. The photodiode cathode is connected to a high impedance feedback loop, including an output transistor, which is connected back to the photodiode anode. In a preferred embodiment, further included is a feedback circuit gain controlling transistor having a base driven by the feedback circuit and a current electrode connected to the source of the first FET.

    摘要翻译： 一种光电放大器，包括具有连接到第一FET的栅极的阳极和连接到第二FET的栅极的阴极的光电二极管，其中第二FET具有源极栅极互连以便自偏置。 光电二极管阴极连接到高阻抗反馈环路，包括连接到光电二极管阳极的输出晶体管。 在优选实施例中，还包括反馈电路增益控制晶体管，其具有由反馈电路驱动的基极和连接到第一FET的源极的电流电极。

    Camera system with a photometering device and an external operating device
    8.
    发明授权
    Camera system with a photometering device and an external operating device 失效
    具有测光装置和外部操作装置的相机系统

    公开(公告)号：US07313323B2

    公开(公告)日：2007-12-25

    申请号：US11017789

    申请日：2004-12-22

    申请人： Tadahisa Ohkura ,  Yutaka Ohsawa ,  Shigeru Iwamoto ,  Hiroyuki Takahashi

    发明人： Tadahisa Ohkura ,  Yutaka Ohsawa ,  Shigeru Iwamoto ,  Hiroyuki Takahashi

    IPC分类号： G03B7/00

    CPC分类号： G03B7/20 ,  G03B7/085 ,  G03B7/097

    摘要： A camera system includes a camera body including a photometering device and an external operating device, and a photographing lens which is detachably attached to the camera body, the photographing lens including an aperture setting device for selecting an auto aperture setting and at least one fixed aperture setting. A full-aperture photometering operation is performed when the aperture setting device is positioned at the auto aperture setting, and a stop-down photometering operation is performed in response to an operation of the external operating device when the aperture setting device is positioned at the fixed aperture setting.

    摘要翻译： 照相机系统包括：照相机主体，包括测光装置和外部操作装置;以及拍摄透镜，其可拆卸地安装在照相机主体上，拍摄透镜包括用于选择自动光圈设定的光圈设定装置和至少一个固定光圈 设置。 当光圈设置装置位于自动光圈设置时，执行全光圈测光操作，并且当光圈设置装置位于固定的位置时响应于外部操作装置的操作执行停止测光操作 光圈设置。

    Methods of treating patients suffering from movement disorders
    9.
    发明申请
    Methods of treating patients suffering from movement disorders 有权

    公开(公告)号：US20060178379A1

    公开(公告)日：2006-08-10

    申请号：US11326414

    申请日：2006-01-06

    申请人： Hiroshi Kase ,  Akihisa Mori ,  Yutaka Waki ,  Yutaka Ohsawa ,  Akira Karasawa ,  Yoshihisa Kuwana

    发明人： Hiroshi Kase ,  Akihisa Mori ,  Yutaka Waki ,  Yutaka Ohsawa ,  Akira Karasawa ,  Yoshihisa Kuwana

    IPC分类号： A61K31/522 ,  A61K31/198 ,  A61K31/137

    CPC分类号： A61K31/522 ,  A61K9/0019 ,  A61K9/20 ,  A61K9/48 ,  A61K31/198 ,  A61K45/06

    摘要： The present invention is directed to methods of treating movement disorders by administering an effective amount of one or more adenosine A2A receptor antagonists to a patient in need thereof. The present invention also provides methods of decreasing the adverse effects of L-DOPA in patients receiving L-DOPA therapy in the treatment of Parkinson's disease. The present invention further provides methods and compositions for treating Parkinson's disease patients with sub-clinically effective doses of L-DOPA by combining L-DOPA treatment with an effective amount of one or more adenosine A2A receptor antagonists (i.e., L-DOPA sparing effect). The present invention further provides methods of effective treatment of Parkinson's disease by co-administering at least one adenosine A2A receptor antagonist, L-DOPA and a dopamine agonist and/or a COMT inhibitor and/or a MAO inhibitor. The present invention further provides methods of prolonging effective treatment of Parkinson's disease by administering an adenosine A2A receptor antagonist singly or together with a dopamine agonist, and/or a COMT inhibitor, and/or a MAO inhibitor without prior or subsequent administration of L-DOPA, delaying or removing on-set of L-DOPA motor complication.

    Digital camera
    10.
    发明申请
    Digital camera 有权
    数码相机

    公开(公告)号：US20050219406A1

    公开(公告)日：2005-10-06

    申请号：US11091433

    申请日：2005-03-29

    申请人： Yutaka Ohsawa

    发明人： Yutaka Ohsawa

    IPC分类号： G03B7/26 ,  G01R31/36 ,  G03B7/093 ,  G03B17/02 ,  G03B17/18 ,  G03B17/38 ,  H04N1/00 ,  H04N5/225 ,  H04N5/232 ,  H04N5/235 ,  H04N101/00

    CPC分类号： H04N5/23241 ,  H04N5/232 ,  H04N5/235

    摘要： A digital camera includes an image pickup device which converts incident light of an object image into an electrical signal during an exposure operation; a processor which captures the electrical signal, and thereafter generates a digital image from the electrical signal; a battery checking device which performs a battery check process for determining whether a battery voltage of the digital camera is lower than a predetermined voltage level; a controller which forcibly terminates the exposure operation when the battery checking device determines that the battery voltage drops below the predetermined voltage level during the exposure operation, and subsequently makes the processor start capturing the electrical signal in order to generate a backup digital image; and a warning device which warns a user that the exposure operation is forcibly terminated due to a shortage of the battery voltage and that the backup digital image is underexposed, in the case where the exposure is forcibly terminated.

    摘要翻译： 数码相机包括：图像拾取装置，其在曝光操作期间将对象图像的入射光转换成电信号; 捕获电信号的处理器，然后从电信号产生数字图像; 电池检查装置，其执行用于确定所述数字照相机的电池电压是否低于预定电压电平的电池检查处理; 当曝光操作期间电池检查装置确定电池电压降低到预定电压电平以下时，强制终止曝光操作的控制器，随后使处理器开始捕捉电信号以产生备用数字图像; 以及在强制终止曝光的情况下，由于电池电压不足和备用数字图像曝光不足而警告用户曝光操作被强制终止的警告装置。