公开(公告)号：US4657540A

公开(公告)日：1987-04-14

申请号：US757770

申请日：1985-07-23

申请人： Tomiyuki Iwamoto ,  Naoki Hayakawa ,  Shigeru Matsubara

发明人： Tomiyuki Iwamoto ,  Naoki Hayakawa ,  Shigeru Matsubara

IPC分类号： B65D81/20 ,  A61J1/00 ,  A61J1/05 ,  A61J1/10 ,  A61J1/14 ,  A61J1/16 ,  A61L2/00 ,  A61L2/06 ,  A61L2/07 ,  A61L2/26 ,  A61B19/00

CPC分类号： A61J1/10 ,  A61J1/1462 ,  A61L2/0023 ,  A61L2/07 ,  A61L2/26 ,  A61J1/16

摘要： A high pressure steam sterilized plastic container holding an infusion solution therein is prepared first by providing a flexible container made of plastic material and holding an infusion solution. The container is then sterilized in a saturated steam atmosphere which is pressurized by a gas inert to the infusion solution and does not contain oxygen. The infusion solution in the container is not deteriorated after the sterilization.

摘要翻译： 首先通过提供由塑料材料制成的柔性容器并保持输液来制备在其中容纳浸液的高压蒸汽消毒塑料容器。 然后将容器在饱和蒸汽气氛中灭菌，该饱和蒸汽气氛通过对输注溶液惰性的气体加压并且不含氧。 灭菌后容器内的输液不会变质。

公开(公告)号：US4548605A

公开(公告)日：1985-10-22

申请号：US447689

申请日：1982-12-07

申请人： Tomiyuki Iwamoto ,  Naoki Hayakawa ,  Haruo Honda ,  Teppei Maruyama

发明人： Tomiyuki Iwamoto ,  Naoki Hayakawa ,  Haruo Honda ,  Teppei Maruyama

IPC分类号： B65B55/10 ,  A61J1/00 ,  A61J1/05 ,  A61J1/16 ,  A61L2/00 ,  B65B31/02 ,  B65B55/02 ,  B65B55/06 ,  B65D81/24

CPC分类号： A61J1/10 ,  A61J1/1462 ,  A61L2/0023 ,  B65B55/02 ,  A61J1/16 ,  A61M2207/00

摘要： A plastic container containing an infusion solution which may not allow deterioration of the infusion solution over a long period of time, is prepared by providing a container which is made of a flexible plastic material having a heat resistance able to withstand heat of autoclaving sterilization and which holds an infusion solution containing components which may easily deteriorate upon contact with oxygen; the container is packaged with a first packaging material which consists of a plastic material having a gas permeability and a heat resistance able to withstand the heat of autoclaving sterilization. The container packaged with the first packaging material is sterilized by autoclaving in an atmosphere of saturated steam containing substantially no oxygen. The packaged and sterilized container is cooled while substantially maintaining a pressure of autoclaving sterilization by introducing an inert gas into the atmosphere. The container is further packaged with a second packaging material which has a high oxygen gas impermeability.

摘要翻译： 通过提供容器，该容器由具有能承受高压灭菌灭菌的热的耐热性的柔性塑料材料制成的容器制备，该容器含有可能不允许输注溶液长时间劣化的输注溶液的塑料容器， 保持含有与氧接触可能容易恶化的成分的输液; 容器与第一包装材料一起包装，该包装材料由具有气体透过性和耐热性的塑料材料组成，能够承受高压灭菌灭菌的热量。 用第一包装材料包装的容器通过在基本上不含氧气的饱和蒸汽气氛中高压灭菌来灭菌。 将包装和灭菌的容器冷却，同时通过将惰性气体引入大气中而基本保持高压灭菌灭菌的压力。 该容器进一步包装有具有高氧气不透性的第二包装材料。