公开(公告)号：US08979759B2

公开(公告)日：2015-03-17

申请号：US13521776

申请日：2011-02-02

申请人： Tomohiko Tanaka ,  Takashi Azuma ,  Marie Tabaru ,  Kunio Hashiba

发明人： Tomohiko Tanaka ,  Takashi Azuma ,  Marie Tabaru ,  Kunio Hashiba

IPC分类号： A61B8/04 ,  A61B8/08 ,  A61B8/14

CPC分类号： A61B8/0883 ,  A61B8/04 ,  A61B8/485 ,  A61B8/486

摘要： Ultrasonic imaging device noninvasively measures cardiac muscle stiffness or intracardiac pressure. The device includes: an ultrasonic probe (2) transmitting and receiving ultrasonic waves to and from the heart; a signal-processing section (15) processing reflected echo signals; a display section (14) displaying results of signal processing as an image; and an input section (10) setting a predetermined point on the image. The signal-processing section (15) includes: a shape-extracting section (152) perceiving information on the shape of the heart from the reflected echo signals; a natural-frequency detecting section (153) detecting natural frequency of the heart from the reflected echo signals; and a calculating section (154) calculating stiffness of the cardiac muscle or the intracardiac pressure, wherein the calculating section (154) accurately calculates the stiffness of the cardiac muscle from the natural frequency of the heart and calculates the intracardiac pressure from the stiffness of the cardiac muscle that has been calculated.

摘要翻译： 超声成像装置无侵害性地测量心肌僵硬或心内压。 该装置包括：超声波探头（2），用于向心脏和/或从心脏传递和接收超声波; 处理反射回波信号的信号处理部（15） 显示部分（14），显示作为图像的信号处理的结果; 以及设置图像上的预定点的输入部（10）。 信号处理部（15）包括：形状提取部（152），从反射的回波信号中感知关于心脏的形状的信息; 自然频率检测部分，从反射回波信号中检测心脏的固有频率; 以及计算心肌的心率或心脏内压的计算部（154），其中，计算部（154）从心脏的固有频率精确地计算心肌的刚度，并从心脏的刚度算出心内压 已经计算出的心肌。

公开(公告)号：US20120296209A1

公开(公告)日：2012-11-22

申请号：US13521776

申请日：2011-02-02

申请人： Tomohiko Tanaka ,  Takashi Azuma ,  Marie Tabaru ,  Kunio Hashiba

发明人： Tomohiko Tanaka ,  Takashi Azuma ,  Marie Tabaru ,  Kunio Hashiba

IPC分类号： A61B8/04 ,  A61B8/08 ,  A61B8/14

CPC分类号： A61B8/0883 ,  A61B8/04 ,  A61B8/485 ,  A61B8/486

摘要： Provided is an ultrasonic imaging device that noninvasively measures the stiffness of the cardiac muscle, which is the heart muscle, or intracardiac pressure, which is the blood pressure inside the heart. The ultrasonic imaging device includes: an ultrasonic probe (2) that transmits and receives ultrasonic waves to and from the heart, which is the target organ inside the body; a signal-processing section (15) that processes reflected echo signals received by the ultrasonic probe; a display section (14) that displays the results of signal processing as an image; and an input section (10) for setting a predetermined point on the image displayed on the display section. The signal-processing section (15) includes: a shape-extracting section (152) that perceives information on the shape of the heart from the reflected echo signals; a natural-frequency detecting section (153) that detects the natural frequency of the heart from the reflected echo signals; and a calculating section (154) that calculates the stiffness of the cardiac muscle or the intracardiac pressure, wherein the calculating section (154) accurately calculates the stiffness of the cardiac muscle from the natural frequency of the heart and calculates the intracardiac pressure from the stiffness of the cardiac muscle that has been calculated.

摘要翻译： 提供了一种超声波成像装置，其非侵入性地测量作为心脏肌肉的心肌的刚度或作为心脏内的血压的心内压。 超声波成像装置包括：超声波探头（2），其将超声波与作为体内目标器官的心脏进行超声波的接收; 处理由超声波探头接收的反射回波信号的信号处理部分（15）; 显示部分（14），其将信号处理的结果显示为图像; 以及用于设置显示在显示部分上的图像上的预定点的输入部分（10）。 信号处理部（15）包括：形状提取部（152），从反射的回波信号中感知关于心脏的形状的信息; 自然频率检测部分，从反射回波信号中检测心脏的固有频率; 以及计算心脏的硬度或心内压力的计算部（154），其中计算部（154）从心脏的固有频率精确地计算心肌的刚度，并从刚度计算心内压 的心脏肌肉。

公开(公告)号：US09259205B2

公开(公告)日：2016-02-16

申请号：US13990063

申请日：2011-11-28

申请人： Tomohiko Tanaka ,  Takashi Azuma ,  Kunio Hashiba

发明人： Tomohiko Tanaka ,  Takashi Azuma ,  Kunio Hashiba

IPC分类号： A61B8/00 ,  A61B8/06 ,  A61B8/08

CPC分类号： A61B8/06 ,  A61B8/0883 ,  A61B8/0891 ,  A61B8/5246

摘要： Provided is a technology which quantitatively measures blood flow in the vicinity of circulatory organs. An ultrasound image capture device according to the present invention removes an image portion corresponding to an organ shape by taking the difference of a multi-frame ultrasound image, and thereafter computes a measured value of a blood flow velocity vector on the basis of a plurality of images at different timings (as per FIG. 3).

摘要翻译： 提供了一种定量测量循环器官附近血液流量的技术。 根据本发明的超声波图像捕获装置通过取多帧超声波图像的差异去除对应于器官形状的图像部分，然后基于多个超帧图像计算血流速度矢量的测量值 不同时间的图像（如图3所示）。

公开(公告)号：US20130289408A1

公开(公告)日：2013-10-31

申请号：US13990063

申请日：2011-11-28

申请人： Tomohiko Tanaka ,  Takashi Azuma ,  Kunio Hashiba

发明人： Tomohiko Tanaka ,  Takashi Azuma ,  Kunio Hashiba

IPC分类号： A61B8/06

CPC分类号： A61B8/06 ,  A61B8/0883 ,  A61B8/0891 ,  A61B8/5246

摘要： Provided is a technology which quantitatively measures blood flow in the vicinity of circulatory organs. An ultrasound image capture device according to the present invention removes an image portion corresponding to an organ shape by taking the difference of a multi-frame ultrasound image, and thereafter computes a measured value of a blood flow velocity vector on the basis of a plurality of images at different timings (as per FIG. 3).

摘要翻译： 提供了一种定量测量循环器官附近血液流量的技术。 根据本发明的超声波图像捕获装置通过取多帧超声波图像的差异去除对应于器官形状的图像部分，然后基于多个超帧图像计算血流速度矢量的测量值 不同时间的图像（如图3所示）。

公开(公告)号：US09538989B2

公开(公告)日：2017-01-10

申请号：US14342970

申请日：2012-08-01

申请人： Tomohiko Tanaka ,  Kunio Hashiba

发明人： Tomohiko Tanaka ,  Kunio Hashiba

IPC分类号： A61B8/14 ,  A61B8/08 ,  A61B8/06 ,  A61B8/04 ,  A61B8/00

CPC分类号： A61B8/5223 ,  A61B8/04 ,  A61B8/06 ,  A61B8/065 ,  A61B8/0883 ,  A61B8/0891 ,  A61B8/14 ,  A61B8/463 ,  A61B8/488 ,  A61B8/5207

摘要： In ultrasonic imaging, a physically consistent value of blood flow velocity is measured in the vicinity of body tissues. The ultrasound imaging apparatus comprises a shape extraction part for recognizing shape data of biological tissues by using echo signals reflected from a test subject irradiated with ultrasonic waves, a flow velocity distribution acquisition part for detecting blood flow velocities in the vicinity of the tissues from the echo signals, and a velocity determination part for extracting velocity information desired by a tester (objective velocity information). The velocity determination part sets a model of the objective blood flow, and determines a velocity of actually measured velocity distribution consistent with velocity distribution estimated from the model.

摘要翻译： 在超声波成像中，在身体组织附近测量物理上一致的血流速度值。 超声波成像装置包括：形状提取部，其通过使用从超声波照射的被检体所反射的回波信号来识别生物体的形状数据;流速分布获取部，用于检测来自回波的组织附近的血流速度 信号和用于提取测试仪所需的速度信息的速度确定部（目标速度信息）。 速度确定部分设定目标血流的模型，并确定与模型估计的速度分布一致的实际测量的速度分布的速度。

公开(公告)号：US20120041313A1

公开(公告)日：2012-02-16

申请号：US13265773

申请日：2010-04-23

申请人： Tomohiko Tanaka ,  Kunio Hashiba ,  Mariko Yamamoto ,  Osamu Mori

发明人： Tomohiko Tanaka ,  Kunio Hashiba ,  Mariko Yamamoto ,  Osamu Mori

IPC分类号： A61B8/14

CPC分类号： A61B8/08 ,  A61B8/04 ,  A61B8/065 ,  A61B8/0883 ,  A61B8/488 ,  A61B8/5223

摘要： The absolute pressure inside the heart with respect to heartbeat time phase is measured non-invasively or with minimal invasion. An ultrasonic diagnostic device comprising: a pressure sensor that detects artery pressure non-invasively; a reference pressure computation part that converts the artery pressure into absolute reference pressure with respect to a reference point; a spatial pressure difference calculation part that calculates a spatial pressure difference between the reference point and a location distinct from the reference point; and an absolute pressure computation part that calculates intracardiac absolute pressure using a shape image, the reference pressure, and the spatial pressure difference.

摘要翻译： 相对于心跳时间相位心脏内的绝对压力是非侵入性的或以最小的入侵测量的。 一种超声波诊断装置，包括：非侵入性地检测动脉压的压力传感器; 参考压力计算部分，其将动脉压力相对于参考点转换为绝对参考压力; 空间压力差计算部，其计算所述基准点与不同于所述参考点的位置之间的空间压力差; 以及使用形状图像，基准压力和空间压力差计算心内绝对​​压力的绝对压力计算部。

公开(公告)号：US20140236008A1

公开(公告)日：2014-08-21

申请号：US14342970

申请日：2012-08-01

申请人： Tomohiko Tanaka ,  Kunio Hashiba

发明人： Tomohiko Tanaka ,  Kunio Hashiba

IPC分类号： A61B8/08 ,  A61B8/04 ,  A61B8/06 ,  A61B8/00 ,  A61B8/14

CPC分类号： A61B8/5223 ,  A61B8/04 ,  A61B8/06 ,  A61B8/065 ,  A61B8/0883 ,  A61B8/0891 ,  A61B8/14 ,  A61B8/463 ,  A61B8/488 ,  A61B8/5207

摘要： In ultrasonic imaging, a physically consistent value of blood flow velocity is measured in the vicinity of body tissues. The ultrasound imaging apparatus comprises a shape extraction part for recognizing shape data of biological tissues by using echo signals reflected from a test subject irradiated with ultrasonic waves, a flow velocity distribution acquisition part for detecting blood flow velocities in the vicinity of the tissues from the echo signals, and a velocity determination part for extracting velocity information desired by a tester (objective velocity information). The velocity determination part sets a model of the objective blood flow, and determines a velocity of actually measured velocity distribution consistent with velocity distribution estimated from the model.

摘要翻译： 在超声波成像中，在身体组织附近测量物理上一致的血流速度值。 超声波成像装置包括：形状提取部，其通过使用从超声波照射的被检体所反射的回波信号来识别生物体的形状数据;流速分布获取部，用于检测来自回波的组织附近的血流速度 信号和用于提取测试仪所需的速度信息的速度确定部（目标速度信息）。 速度确定部分设定目标血流的模型，并确定与模型估计的速度分布一致的实际测量的速度分布的速度。

公开(公告)号：US09678245B2

公开(公告)日：2017-06-13

申请号：US13475435

申请日：2012-05-18

申请人： Tomohiko Tanaka ,  Michiaki Fuji ,  Nao Murakami ,  Takashi Shimizu

发明人： Tomohiko Tanaka ,  Michiaki Fuji ,  Nao Murakami ,  Takashi Shimizu

IPC分类号： B32B27/36 ,  C08G64/06 ,  G02B1/04 ,  C08J5/18 ,  G02B5/30 ,  G02F1/13363

摘要： A polycarbonate resin film of the present invention is formed from a polycarbonate resin which contains at least a constitutional unit derived from a dihydroxy compound having a bonded structure represented by the following structural formula (1) and satisfies the following expression (2) when subjected to a tensile test at a standard stretching temperature for the polycarbonate resin and at a pulling speed (strain rate) of 1,000%/min. [Chem. 1] CH2—O  (1) (No hydrogen atom is bonded to the oxygen atom contained in the structural formula (1).) 0.9≦[(lower yield stress in tension)/(upper yield stress in tension)]≦1  (2).

公开(公告)号：US20100190953A1

公开(公告)日：2010-07-29

申请号：US12305660

申请日：2007-06-14

申请人： Michiaki Fuji ,  Minako Akita ,  Tomohiko Tanaka

发明人： Michiaki Fuji ,  Minako Akita ,  Tomohiko Tanaka

IPC分类号： C08G64/00 ,  C08G65/00

CPC分类号： C08G64/06 ,  C08G64/0208 ,  C08G64/305 ,  C08L69/005 ,  C08L2666/18

摘要： The object is to provide a polycarbonate copolymer having excellent mechanical strength, good heat resistance, a low refractive index, a large Abbe number, a low berefringence and excellent transparency and containing a plant-derived raw material. Disclosed is a polycarbonate copolymer which comprises a constituent unit derived from a dihydroxy compound represented by the general formula (1) and a constituent unit derived from an alicyclic dihydroxy compound and has an Abbe number of 50 or greater and “a 5% heating weight loss temperature” (a temperature at which the 5% weight loss under heating is observed) of 340° C. or higher. Also disclosed is a process for producing the polycarbonate copolymer by reacting a dihydroxy compound represented by the general formula (1) and an alicyclic dihydroxy compound with a carbonate diester in the presence of a polymerization catalyst.

摘要翻译： 本发明的目的是提供具有优异的机械强度，良好的耐热性，低折射率，大的阿贝数，低的光辉度和优异的透明性并且含有植物来源的原料的聚碳酸酯共聚物。 公开了一种聚碳酸酯共聚物，其包含衍生自由通式（1）表示的二羟基化合物的结构单元和衍生自脂环族二羟基化合物的结构单元，并且具有50以上的阿贝数和“5％的加热失重 温度“（观察到加热时5％重量损失的温度）为340℃以上。 还公开了通过在聚合催化剂存在下使由通式（1）表示的二羟基化合物与脂环族二羟基化合物与碳酸二酯反应制备聚碳酸酯共聚物的方法。

公开(公告)号：US20090215933A1

公开(公告)日：2009-08-27

申请号：US11988165

申请日：2006-06-07

申请人： Atsushi Kasai ,  Masahiro Nukui ,  Tomohiko Tanaka ,  Atsushi Fujimura

发明人： Atsushi Kasai ,  Masahiro Nukui ,  Tomohiko Tanaka ,  Atsushi Fujimura

IPC分类号： C08L67/02 ,  C08G63/199 ,  C08G63/85 ,  C08K5/49

CPC分类号： C08G63/199 ,  C08G63/85 ,  C08K5/49 ,  C08L67/02 ,  C08L69/00 ,  C08L2666/18

摘要： An alicyclic polyester which is suitable for use as an optical material, low in coloration, satisfactory in thermal stability and hydrolytic stability, and reduced in foreign-matter content; and a resin composition comprising the alicyclic polyester and a polycarbonate. The alicyclic polyester is produced from a dicarboxylic acid ingredient comprising an alicyclic dicarboxylic acid as a major component and a diol ingredient comprising an alicyclic diol as a major component with the aid of a polycondensation catalyst comprising a titanium compound and an alkaline earth metal compound. The alicyclic polyester has a titanium content in terms of metal atom amount of 1-25 wt. ppm, excluding 25 wt. ppm, a ratio of the weight of the alkaline earth metal (M) to the weight of the titanium in terms of metal atom amount ratio, (M/Ti), of 0.25-1.0, and an intrinsic viscosity of 0.4 dl/g or higher.

摘要翻译： 适合用作光学材料，着色度低，热稳定性和水解稳定性好的脂环族聚酯，异物含量降低; 和包含脂环族聚酯和聚碳酸酯的树脂组合物。 脂环族聚酯由包含脂环族二羧酸作为主要成分的二羧酸成分和以含有钛化合物和碱土金属化合物的缩聚催化剂为主要成分的二醇成分构成。 脂环族聚酯的钛含量以金属原子量计为1-25wt。 ppm，不包括25wt。 ppm，以金属原子量比计，碱土金属（M）与钛的重量比（M / Ti）为0.25-1.0，特性粘度为0.4dl / g，或 更高。