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公开(公告)号：US07217793B2
公开(公告)日：2007-05-15
申请号：US11223974
申请日：2005-09-13
CPC分类号： G01N33/92 , C07K14/43536
摘要： Proteins useful as sphingomyelin detecting probes, which specifically recognize sphingomyelin and have low cytotoxicity. The proteins of the present invention may be obtained by deletion of between about 110 to 170 amino acid residues from the N terminal or C terminal of earthworm toxin Lysenin 1. Kits for detecting sphingomyelin are also disclosed.
摘要翻译： 可用作鞘磷脂检测探针的蛋白质，其特异性识别鞘磷脂并具有低细胞毒性。 本发明的蛋白质可以通过从蚯蚓毒素赖欣素1的N末端或C末端缺失约110至170个氨基酸残基而获得。还公开了用于检测鞘磷脂的试剂盒。
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公开(公告)号：US06995236B2
公开(公告)日：2006-02-07
申请号：US10138634
申请日：2002-05-06
CPC分类号： G01N33/92 , C07K14/43536
摘要： An object of the present invention is to provide a protein useful as a sphingomyelin detecting probe, which specifically recognizes sphingomyelin and has low cytotoxicity. The present invention provides a protein which has an amino acid sequence having, as the amino acid sequence from the 1st to the 48th amino acid, the amino acid sequence from the 1st to the 48th amino acid in Lysenin 1, and as the amino acid sequence from the 49th to the 298th amino acid, the amino acid sequence from the 51st to the 300th amino acid in Lysenin 3; and a protein which is obtained by deleting N terminal and/or C terminal from earthworm toxins Lysenin 1 or 3, and which specifically recognizes sphingomyelin.
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公开(公告)号：US20060014217A1
公开(公告)日：2006-01-19
申请号：US11223974
申请日：2005-09-13
CPC分类号： G01N33/92 , C07K14/43536
摘要： An object of the present invention is to provide a protein useful as a sphingomyelin detecting probe, which specifically recognizes sphingomyelin and has low cytotoxicity. The present invention provides a protein which has an amino acid sequence having, as the amino acid sequence from the 1st to the 48th amino acid, the amino acid sequence from the 1st to the 48th amino acid in Lysenin 1, and as the amino acid sequence from the 49th to the 298th amino acid, the amino acid sequence from the 51st to the 300th amino acid in Lysenin 3; and a protein which is obtained by deleting N terminal and/or C terminal from earthworm toxins Lysenin 1 or 3, and which specifically recognizes sphingomyelin.
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公开(公告)号：US20130115625A1
公开(公告)日：2013-05-09
申请号：US13697402
申请日：2011-05-13
申请人： Toshihide Kobayashi , Tetsuyuki Kobayashi , Kozo Nishibori , Atsushi Kurahashi , Fumihiro Fujimori
发明人： Toshihide Kobayashi , Tetsuyuki Kobayashi , Kozo Nishibori , Atsushi Kurahashi , Fumihiro Fujimori
IPC分类号： C07K14/375 , C07K16/14
CPC分类号： C07K14/375 , A61K38/00 , C07K16/14 , G01N33/92 , G01N2405/08
摘要： A protein being the following (A), (B), or (C): (A) a protein represented by the amino acid sequence of SEQ ID NO: 1; (B) a protein represented by an amino acid sequence in which one or a plurality of amino acid is substituted, deleted, inserted or added in the amino acid sequence of SEQ ID NO: 1, the protein having binding activity specific for a mixture of a sphingolipid and cholesterol; or (C) a protein represented by an amino acid sequence being at least 70% identical to the amino acid sequence of SEQ ID NO: 1.
摘要翻译： （A），（B）或（C）的蛋白质：（A）由SEQ ID NO：1的氨基酸序列表示的蛋白质。 （B）由氨基酸序列表示的蛋白质，其中一个或多个氨基酸被取代，缺失，插入或添加到SEQ ID NO：1的氨基酸序列中，所述蛋白具有对于 鞘脂和胆固醇; 或（C）由与SEQ ID NO：1的氨基酸序列至少70％相同的氨基酸序列表示的蛋白质。
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公开(公告)号：US20090079855A1
公开(公告)日：2009-03-26
申请号：US12078919
申请日：2008-04-08
申请人： Taiichi Ito , Toshihide Kobayashi , Kazuya Yamada
发明人： Taiichi Ito , Toshihide Kobayashi , Kazuya Yamada
CPC分类号： H04N9/045 , H04N2209/046 , H04N2209/049
摘要： Calculation is made about standard deviations of portions of high-frequency components GH, RH, and BH along respective predetermined directions. The portions of the high-frequency components GH, RH, and BH represent a prescribed number of pixels including an interpolation pixel located at a position corresponding to none of photosensor pixels in G, R, and B image sensors. The smallest one is detected among the calculated standard deviations. The predetermined direction relating to the detected smallest standard deviation is labeled as a highest-correlation direction in which the highest correlation occurs. Interpolation is implemented in response to portions of the high-frequency components GH, RH, and BH which correspond to the highest-correlation direction to generate a high-frequency interpolation-result signal RGBHI for the interpolation pixel and other pixels. Low-frequency components GL, RL, and BL are combined with the high-frequency interpolation-result signal RGBHI to generate high-definition green, red, and blue signals G(HD), R(HD), and B(HD).
摘要翻译： 对各部分的高频分量GH，RH，BH的各部分的标准偏差进行计算。 高频分量GH，RH和BH的部分表示规定数量的像素，包括位于与G，R和B图像传感器中的任何一个光电传感器像素对应的位置的内插像素。 在计算的标准偏差中检测到最小的一个。 与检测到的最小标准偏差有关的预定方向被标记为发生最高相关性的最高相关方向。 响应于对应于最高相关方向的高频分量GH，RH和BH的部分实现插值，以生成用于内插像素和其他像素的高频内插结果信号RGBHI。 低频分量GL，RL和BL与高频内插结果信号RGBHI组合以产生高分辨率绿色，红色和蓝色信号G（HD），R（HD）和B（HD）。
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公开(公告)号：US20100045824A1
公开(公告)日：2010-02-25
申请号：US12461690
申请日：2009-08-20
IPC分类号： H04N9/68
CPC分类号： H04N5/2351 , H04N5/23293 , H04N5/243
摘要： A video image pickup apparatus (10) includes an image sensor (120), a knee processor (132) for performing a compression in a high-luminance characteristic interval of a picture signal based on an output signal of the image sensor, a block luminance calculator (151) for dividing a frame of image based on the output signal of the solid-state image pickup device into a set of blocks, calculating a set of luminance indices of respective blocks, an extreme extractor (152) for extracting a block having a highest luminance index, together with the luminance index, a display information generator (153) for generating a set of pieces of image information for exposure guide display including an image representing a region of the extracted block and an image representing the luminance index, an image superposer (160) for superposing the set of pieces of image information for exposure guide display on a frame of image based on the compressed picture signal to generate a frame of superposed image, and a view finder (170) for displaying the frame of superposed image.
摘要翻译： 视频摄像装置（10）包括图像传感器（120），膝部处理器（132），用于基于图像传感器的输出信号在图像信号的高亮度特性区间中执行压缩，块亮度 计算器（151），用于将基于固态图像拾取装置的输出信号的图像帧划分成一组块，计算各个块的亮度指标集;极端提取器（152），用于提取具有 最高亮度指数与亮度指数一起，用于生成用于曝光指南显示的一组图像信息的显示信息发生器，包括表示提取的块的区域的图像和表示亮度指数的图像， 图像叠加器（160），用于基于压缩图像信号将用于曝光引导显示的图像信息块叠加在图像帧上以产生叠加图像的帧， 和用于显示叠加图像的帧的取景器（170）。
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公开(公告)号：US20060110781A1
公开(公告)日：2006-05-25
申请号：US10516072
申请日：2003-05-30
CPC分类号： G01N33/92
摘要： An object of the present invention is to provide a novel cholesterol detection reagent comprising a substance which can specifically binds to cholesterol to detect it, and a method for detecting cholesterol using the reagent. The present invention provides a cholesterol detection reagent comprising a polyethylene glycol cholesteryl ether which may be labeled.
摘要翻译： 本发明的目的是提供一种胆固醇检测试剂，其包含能够特异性结合胆固醇进行检测的物质，以及使用该试剂检测胆固醇的方法。 本发明提供一种胆固醇检测试剂，其包含可标记的聚乙二醇胆固醇醚。
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8.发明授权Process for producing compression molded article of lignocellulose type material 失效用于生产木质纤维素型材料的压塑制品的方法
公开(公告)号：US5744079A
公开(公告)日：1998-04-28
申请号：US890292
申请日：1997-07-09
IPC分类号： B27N3/00 , B27N3/08 , C08G18/70 , C08J5/00 , C08L91/06 , C08L97/02 , C09J175/00 , C09J175/04
CPC分类号： C08G18/706 , B27N3/002 , B27N3/083 , C08L97/02 , C08G2125/00 , C08L91/06
摘要： A process is provided for producing a compression molded article of a lignocellulose type material by use of an organic polyisocyanate compound as a binder. The process comprises carrying out adhesion by use of the following components (A) an organic polyisocyanate, (B) an aqueous emulsion of a wax having a melting point ranging from 50.degree. C. to 160.degree. C., and (C) an organic phosphate ester derivative and optionally (D) water. The compression molded article can readily be released from the mold, and has excellent physical properties.
摘要翻译： 提供了一种通过使用有机多异氰酸酯化合物作为粘合剂来生产木质纤维素类材料的压缩成型制品的方法。 该方法包括通过使用以下组分（A）有机多异氰酸酯，（B）熔点为50℃至160℃的蜡的水性乳液和（C）有机聚异氰酸酯 磷酸酯衍生物和任选的（D）水。 压塑制品可以容易地从模具中释放出来，并且具有优异的物理性能。
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公开(公告)号：US08379140B2
公开(公告)日：2013-02-19
申请号：US12461690
申请日：2009-08-20
CPC分类号： H04N5/2351 , H04N5/23293 , H04N5/243
摘要： A video image pickup apparatus (10) includes an image sensor (120), a knee processor (132) for performing a compression in a high-luminance characteristic interval of a picture signal based on an output signal of the image sensor, a block luminance calculator (151) for dividing a frame of image based on the output signal of the solid-state image pickup device into a set of blocks, calculating a set of luminance indices of respective blocks, an extreme extractor (152) for extracting a block having a highest luminance index, together with the luminance index, a display information generator (153) for generating a set of pieces of image information for exposure guide display including an image representing a region of the extracted block and an image representing the luminance index, an image superposer (160) for superposing the set of pieces of image information for exposure guide display on a frame of image based on the compressed picture signal to generate a frame of superposed image, and a view finder (170) for displaying the frame of superposed image.
摘要翻译： 视频摄像装置（10）包括图像传感器（120），膝部处理器（132），用于基于图像传感器的输出信号在图像信号的高亮度特性区间中执行压缩，块亮度 计算器（151），用于将基于固态图像拾取装置的输出信号的图像帧划分成一组块，计算各个块的亮度指标集;极端提取器（152），用于提取具有 最高亮度指数与亮度指数一起，用于生成用于曝光指南显示的一组图像信息的显示信息发生器，包括表示提取的块的区域的图像和表示亮度指数的图像， 图像叠加器（160），用于基于压缩图像信号将用于曝光引导显示的图像信息块叠加在图像帧上以产生叠加图像的帧， 和用于显示叠加图像的帧的取景器（170）。
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公开(公告)号：US07911515B2
公开(公告)日：2011-03-22
申请号：US12078919
申请日：2008-04-08
申请人： Taiichi Ito , Toshihide Kobayashi , Kazuya Yamada
发明人： Taiichi Ito , Toshihide Kobayashi , Kazuya Yamada
CPC分类号： H04N9/045 , H04N2209/046 , H04N2209/049
摘要： Calculation is made about standard deviations of portions of high-frequency components GH, RH, and BH along respective predetermined directions. The portions of the high-frequency components GH, RH, and BH represent a prescribed number of pixels including an interpolation pixel located at a position corresponding to none of photosensor pixels in G, R, and B image sensors. The smallest one is detected among the calculated standard deviations. The predetermined direction relating to the detected smallest standard deviation is labeled as a highest-correlation direction in which the highest correlation occurs. Interpolation is implemented in response to portions of the high-frequency components GH, RH, and BH which correspond to the highest-correlation direction to generate a high-frequency interpolation-result signal RGBHI for the interpolation pixel and other pixels. Low-frequency components GL, RL, and BL are combined with the high-frequency interpolation-result signal RGBHI to generate high-definition green, red, and blue signals G(HD), R(HD), and B(HD).
摘要翻译： 对各部分的高频分量GH，RH，BH的各部分的标准偏差进行计算。 高频分量GH，RH和BH的部分表示规定数量的像素，包括位于与G，R和B图像传感器中的任何一个光电传感器像素对应的位置的内插像素。 在计算的标准偏差中检测到最小的一个。 与检测到的最小标准偏差有关的预定方向被标记为发生最高相关性的最高相关方向。 响应于对应于最高相关方向的高频分量GH，RH和BH的部分实现插值，以生成用于内插像素和其他像素的高频内插结果信号RGBHI。 低频分量GL，RL和BL与高频内插结果信号RGBHI组合以产生高分辨率绿色，红色和蓝色信号G（HD），R（HD）和B（HD）。
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