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    Oral medicament for improvement in going to sleep or waking
    1.
    发明申请
    Oral medicament for improvement in going to sleep or waking 审中-公开
    用于改善睡眠或醒来的口服药物

    公开(公告)号：US20060258746A1

    公开(公告)日：2006-11-16

    申请号：US11272107

    申请日：2005-11-08

    申请人： Toshikazu Kamiya ,  Takeshi Shibasaki ,  Asuka Otofuji ,  Yasushi Sakai ,  Akemi Ogawa ,  Miho Komatsu

    发明人： Toshikazu Kamiya ,  Takeshi Shibasaki ,  Asuka Otofuji ,  Yasushi Sakai ,  Akemi Ogawa ,  Miho Komatsu

    IPC分类号： A61K31/198

    CPC分类号： A61K31/198

    摘要： A person, who has symptoms including difficulty in going to sleep, feeling languid after waked up or having a hard time awaking, is desirous of a medicament and a nutritional food that can alleviate the symptoms and improve his or her health. Specifically, one object of the present invention is to provide an orally administered agent, a food and drink, or a food additive which can be used for improving the process of going to sleep and waking. An orally administered agent, a food and drink, or a food additive for improving the process of going to sleep and waking, containing ornithine or a salt thereof as an active ingredient can be provided according to the present invention.

    摘要翻译： 患有睡眠困难，睡眠觉醒或醒来困难等症状的人，希望能够减轻症状，改善身体健康的药物和营养食品。 具体地说，本发明的一个目的是提供可用于改善睡眠和醒来过程的口服制剂，食品和饮料或食品添加剂。 根据本发明，可以提供含有鸟氨酸或其盐作为活性成分的口服给药剂，食品饮料或用于改善睡眠和醒来过程的食品添加剂。

    Muscle building agent and preventive or remedy for muscle weakening
    4.
    发明申请
    Muscle building agent and preventive or remedy for muscle weakening 审中-公开
    肌肉建筑代理和预防或补救肌肉减弱

    公开(公告)号：US20060189566A1

    公开(公告)日：2006-08-24

    申请号：US10547075

    申请日：2004-02-26

    申请人： Miho Komatsu ,  Toshikazu Kamiya

    发明人： Miho Komatsu ,  Toshikazu Kamiya

    IPC分类号： A61K31/7072

    CPC分类号： A23K20/153 ,  A23L33/10 ,  A23L33/40 ,  A61K31/7068

    摘要： In accordance with the present invention, there can be provided a muscle building agent, a preventive or therapeutic agent for muscle wasting, food and drink or feed for muscle building or for prevention or treatment of muscle wasting, and a food and drink additive or a feed additive for muscle building or for prevention or treatment of muscle wasting which contain cytidine diphosphate choline or a salt thereof.

    摘要翻译： 根据本发明，可以提供肌肉发育剂，用于肌肉消瘦的预防或治疗剂，用于肌肉建造的食物和饮料或饲料或用于预防或治疗肌肉消瘦的食物和饮料添加剂或 用于肌肉建设的饲料添加剂或用于预防或治疗含有胞苷二磷酸胆碱或其盐的肌肉消瘦的饲料添加剂。

    METHOD OF IMPROVING STORAGE STABILITY OF SUBSTANCE
    5.
    发明申请
    METHOD OF IMPROVING STORAGE STABILITY OF SUBSTANCE 审中-公开
    改善物质储存稳定性的方法

    公开(公告)号：US20090082305A1

    公开(公告)日：2009-03-26

    申请号：US11909328

    申请日：2006-03-30

    申请人： Toshikazu Kamiya ,  Masao Kimura ,  Yasushi Sakai

    发明人： Toshikazu Kamiya ,  Masao Kimura ,  Yasushi Sakai

    IPC分类号： A61K31/7084 ,  A61K31/34 ,  A23K1/16 ,  A23L1/48

    CPC分类号： A61K9/2009 ,  A61K9/2013 ,  A61K9/2054 ,  A61K31/375 ,  A61K31/7084

    摘要： The present invention relates to a method of improving storage stability of reduced form of nicotinamide adenine dinucleotide, reduced form of nicotinamide adenine dinucleotide phosphate, or a salt thereof, or ascorbic acid, an ascorbic acid derivative, or a salt thereof, which comprises allowing the substance to coexist with an L-arginine acidic amino acid salt, a composition containing the substance and an L-arginine acidic amino acid salt, a process for producing the composition, and a method of storing the substance in the presence of an L-arginine acidic amino acid salt.

    摘要翻译： 本发明涉及一种改善烟酰胺腺嘌呤二核苷酸，还原型烟酰胺腺嘌呤二核苷酸磷酸酯或其盐或抗坏血酸，抗坏血酸衍生物或其盐的还原形式的储存稳定性的方法，其包括使 物质与L-精氨酸酸性氨基酸盐共存，含有该物质和L-精氨酸酸性氨基酸盐的组合物，该组合物的制造方法以及在L-精氨酸存在下将物质进行存储的方法 酸性氨基酸盐。

    TABLET COMPRISING ORNITHINE HYDROCHLORIDE
    8.
    发明申请
    TABLET COMPRISING ORNITHINE HYDROCHLORIDE 审中-公开
    包含异丙基氯化物的片剂

    公开(公告)号：US20090028937A1

    公开(公告)日：2009-01-29

    申请号：US11814828

    申请日：2006-01-30

    申请人： Toshikazu Kamiya ,  Masao Kimura ,  Yasushi Sakai

    发明人： Toshikazu Kamiya ,  Masao Kimura ,  Yasushi Sakai

    IPC分类号： A61K9/20 ,  A61K31/195

    CPC分类号： A61K9/2018 ,  A61K9/205 ,  A61K31/198

    摘要： The present invention has an object to provide a tablet capable of comprising ornithine hydrochloride in a higher content; and a process for producing the same, and provides the tablet comprising ornithine hydrochloride and maltose, or a linear or cyclic dextrin; and the process for producing a tablet comprising ornithine hydrochloride, which comprises compression molding a mixture comprising ornithine hydrochloride and maltose, or a linear or cyclic dextrin by a direct tableting method.

    摘要翻译： 本发明的目的是提供一种能够含有更高含量的鸟氨酸盐酸盐的片剂， 及其制备方法，提供包含鸟氨酸盐酸盐和麦芽糖的片剂，或线性或环状糊精; 以及包含鸟氨酸盐酸盐的片剂的制造方法，其包括通过直接压片法压缩成型含有鸟氨酸盐酸盐和麦芽糖的混合物，或线性或环状糊精。

    Method of Improving Storage Stability of Dried Microorganisms
    9.
    发明申请
    Method of Improving Storage Stability of Dried Microorganisms 审中-公开
    改善干燥微生物储存稳定性的方法

    公开(公告)号：US20090053798A1

    公开(公告)日：2009-02-26

    申请号：US11909391

    申请日：2006-03-30

    申请人： Toshikazu Kamiya ,  Masao Kimura ,  Yasushi Sakai

    发明人： Toshikazu Kamiya ,  Masao Kimura ,  Yasushi Sakai

    IPC分类号： C12N1/04 ,  A23L1/48

    CPC分类号： C12N1/04

    摘要： The present invention relates to a method of improving storage stability of dried microorganisms, such as dried lactic acid bacteria, by allowing the dried microorganisms to coexist with an L-arginine acidic amino acid salt, a composition comprising dried microorganisms and an L-arginine acidic amino acid salt and a process for producing the same, and a method of storing dried microorganisms in the presence of an L-arginine acidic amino acid salt. The storage stability of dried microorganisms can be improved by allowing the dried microorganisms to coexist with an L-arginine acidic amino acid salt.

    摘要翻译： 本发明涉及通过使干燥的微生物与L-精氨酸酸性氨基酸盐共存，包含干燥的微生物的组合物和L-精氨酸的酸性化合物来提高干燥的微生物如干燥的乳酸菌的储存稳定性的方法 氨基酸盐及其制备方法，以及在L-精氨酸酸性氨基酸盐存在下储存干燥的微生物的方法。 通过使干燥的微生物与L-精氨酸酸性氨基酸盐共存，可以提高干燥微生物的储存稳定性。

    Insulin resistance improving agent
    10.
    发明授权
    Insulin resistance improving agent 有权
    胰岛素抵抗改善剂

    公开(公告)号：US08097635B2

    公开(公告)日：2012-01-17

    申请号：US12440807

    申请日：2007-09-19

    申请人： Mika Sumi ,  Fumiko Ogino ,  Toshikazu Kamiya ,  Masahiko Nakano ,  Kazutoshi Kikkawa

    发明人： Mika Sumi ,  Fumiko Ogino ,  Toshikazu Kamiya ,  Masahiko Nakano ,  Kazutoshi Kikkawa

    IPC分类号： A61K31/44

    CPC分类号： A61K31/437 ,  A23G3/364 ,  A23G4/12 ,  A23L33/10 ,  A23V2002/00 ,  A23V2200/328 ,  C07D471/04 ,  Y10S514/866

    摘要： An object of the present invention is to provide a safe and highly effective insulin resistance improving agent or therapeutic agent for type II diabetes. According to the present invention, an insulin resistance improving agent or a therapeutic agent for type II diabetes comprising a compound represented by general formula (I) (wherein R1, R2, and R3 are the same as or different from each other, and each represents lower alkyl, lower alkenyl, lower alkynyl, aralkyl, araryl, phenyl, or a hydrogen atom) or a salt thereof as an active ingredient can be provided.

    摘要翻译： 本发明的目的是提供一种安全高效的胰岛素抵抗改善剂或II型糖尿病治疗剂。 根据本发明，提供一种胰岛素抵抗性改善剂或II型糖尿病治疗剂，其含有通式（I）表示的化合物（其中，R1，R2和R3彼此相同或不同，表示 低级烷基，低级烯基，低级炔基，芳烷基，芳芳基，苯基或氢原子）或其盐作为有效成分。