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公开(公告)号:US06787815B2
公开(公告)日:2004-09-07
申请号:US10341698
申请日:2003-01-14
申请人: Toshio Suda , Hidenori Itoh
发明人: Toshio Suda , Hidenori Itoh
IPC分类号: H01L31111
CPC分类号: H01L23/66 , H01L2223/6627 , H01L2924/0002 , H01L2924/1903 , H01L2924/3011 , H01P1/15 , H01L2924/00
摘要: A switching device for switching a plurality of RF signal lines to deliver a selected one of the RF signals to a receiver has an isolation D/U characteristic as high as 40 dB or higher. The switching device includes a mounting board made of dielectric and a matrix switch mounted thereon and implemented by one or more of SWIC. The RF signal lines in the switching device has no crossing point therebetween on either side of the mounting board to achieve the high isolation D/U ratio or lower cross-talk.
摘要翻译: 用于切换多个RF信号线以将所选择的一个RF信号传送到接收机的开关装置具有高达40dB或更高的隔离D / U特性。 开关装置包括由电介质制成的安装板和安装在其上并由SWIC中的一个或多个实现的矩阵开关。 交换装置中的RF信号线在安装板的任一侧上没有交叉点,以实现高隔离度D / U比或低串扰。
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公开(公告)号:US20070053884A1
公开(公告)日:2007-03-08
申请号:US10557053
申请日:2004-05-14
申请人: Toshio Suda , Atsushi Hirao , Fumio Arai , Kazuhiro Sakurada , Yoji Yamada , Hiroshi Ando , Hidetaka Sato , Hiromi Yokoyama , Masahiko Ishihara
发明人: Toshio Suda , Atsushi Hirao , Fumio Arai , Kazuhiro Sakurada , Yoji Yamada , Hiroshi Ando , Hidetaka Sato , Hiromi Yokoyama , Masahiko Ishihara
CPC分类号: C12N5/0607 , A61K35/12 , C12N5/0663 , C12N5/0665 , C12N5/0667 , C12N5/0668 , C12N2501/10 , C12N2501/235
摘要: Subjects of the present invention are to establish a technology for separating, isolating and culturing a stem cell derived from adult tissue while retaining the in vivo properties thereof, and to provide a preventive and/or therapeutic agent for diseases which accompany tissue injury, which comprises a stem cell derived from adult tissue as an active ingredient. In order to solve the subjects, the present invention provides a stem cell derived from adult tissue which is CD45-negative and CXCR4-positive. Also, the present invention provides a preventive and/or therapeutic agent for diseases which accompany tissue injury, which comprises the stem cell as an active ingredient.
摘要翻译: 本发明的目的是建立一种用于分离,分离和培养来自成体组织的干细胞同时保留其体内特性的技术,并提供用于伴随组织损伤的疾病的预防和/或治疗剂,其包括 来自成体组织的干细胞作为活性成分。 为了解决受试者,本发明提供了源自CD45阴性和CXCR4阳性的成体组织的干细胞。 此外,本发明提供了包含干细胞作为活性成分的伴随组织损伤的疾病的预防和/或治疗剂。
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公开(公告)号:US5418129A
公开(公告)日:1995-05-23
申请号:US803065
申请日:1991-12-06
申请人: Edward Nudelman , Anil Singhal , Henrik Clausen , Sen-itiroh Hakomori , Kazuo Muroi , Toshio Suda , Hisao Nojiri
发明人: Edward Nudelman , Anil Singhal , Henrik Clausen , Sen-itiroh Hakomori , Kazuo Muroi , Toshio Suda , Hisao Nojiri
摘要: A method of producing monoclonal antibodies that bind to tumor-associated gangliosides, the method comprising: (1) immunizing a host with tumor cells; (2) boosting the host with a suspension comprising a mixture of tumor cell membrane and at least one purified lactonized tumor-associated ganglioside; (3) boosting the host with an immunogen comprising a lactone of a tumor associated ganglioside adsorbed on or incorporated into a carrier; (4) fusing immunized cells from the host with myeloma cells to form hybridoma cells; (5) selecting hybridoma cells that produce antibody that binds to the ganglioside of step (3); (6) culturing the selected hybridoma cells; and (7) recovering the antibody.
摘要翻译: 一种产生与肿瘤相关神经节苷脂结合的单克隆抗体的方法,所述方法包括:(1)用肿瘤细胞免疫宿主; (2)用包含肿瘤细胞膜和至少一种经内化的内源性肿瘤相关神经节苷脂的混合物的悬浮液加强宿主; (3)用包含吸附在载体上或结合到载体中的肿瘤相关神经节苷脂的内酯的免疫原来加强宿主; (4)将来自宿主的免疫细胞与骨髓瘤细胞融合以形成杂交瘤细胞; (5)选择产生与步骤(3)的神经节苷脂结合的抗体的杂交瘤细胞; (6)培养所选择的杂交瘤细胞; 和(7)回收抗体。
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公开(公告)号:US07708999B2
公开(公告)日:2010-05-04
申请号:US10500207
申请日:2002-12-26
申请人: Tadafumi Tamura , Masako Uchii , Toshio Suda , Ichiro Miki , Akira Tanaka
发明人: Tadafumi Tamura , Masako Uchii , Toshio Suda , Ichiro Miki , Akira Tanaka
IPC分类号: A61K39/395 , A61K39/00
CPC分类号: C07K16/22 , A61K2039/505 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/76
摘要: The invention provides an agent for preventing or treating arthritis, a cartilage protecting agent, a joint destruction inhibitor and a synovial membrane growth inhibitor comprising an anti-FGF-8 neutralizing antibody as an active ingredient, as well as a diagnostic agent of arthritis comprising an anti-FGF-8 antibody as an active ingredient and a method for judging arthritis using the antibody.
摘要翻译: 本发明提供了用于预防或治疗关节炎的药剂,软骨保护剂,关节破坏抑制剂和包含抗FGF-8中和抗体作为活性成分的滑膜生长抑制剂,以及包括 抗FGF-8抗体作为活性成分,以及使用该抗体判断关节炎的方法。
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公开(公告)号:US20100120481A1
公开(公告)日:2010-05-13
申请号:US12588885
申请日:2009-10-30
申请人: Toshio Suda
发明人: Toshio Suda
IPC分类号: H04M1/00
CPC分类号: H03K17/693 , H03K2217/0054
摘要: A switching circuit that includes a first transfer path and a second transfer path that transfer a high frequency signal, a first transistor that electrically cuts off a common node between the first transfer path and the second transfer path and the first transfer path if the high frequency signal is transferred via the second transfer path, a second transistor that electrically cuts off the common node and the second transfer path if the high frequency signal is transferred via the first transfer path, a first control voltage input terminal that inputs a high-level control voltage if the high frequency signal is transferred via one of the first transfer path and the second transfer path, and a first voltage supply path that supplies a voltage according to the high-level control voltage to the common node.
摘要翻译: 一种开关电路,包括传送高频信号的第一传送路径和第二传送路径,如果高频率,则电切断第一传送路径和第二传送路径之间的公共节点的第一晶体管和第一传送路径 信号经由第二传送路径传送,第二晶体管,如果经由第一传送路径传送高频信号,则电切断公共节点和第二传送路径;第一控制电压输入端,输入高电平控制 如果高频信号通过第一传送路径和第二传送路径中的一个传送,则将电压提供给公共节点,第一电压供应路径根据高电平控制电压提供电压。
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公开(公告)号:US20080119404A1
公开(公告)日:2008-05-22
申请号:US11547567
申请日:2005-03-30
申请人: Kunio Yasunaga , Noboru Yamaji , Toshio Suda , Yuichi Oike
发明人: Kunio Yasunaga , Noboru Yamaji , Toshio Suda , Yuichi Oike
IPC分类号: A61K38/16 , A61P3/10 , A61P3/04 , A61K31/711
CPC分类号: C07K14/515 , A23L33/18 , A61K38/00 , A61K48/00
摘要: An antiobesity agent, an antidiabetic agent, and/or a hypolipidemic agent comprising an angiopoietin-related growth factor (AGF) or a polynucleotide encoding the same as an active ingredient a polypeptide are disclosed. Further, a functional food or a health food for alleviating obesity, diabetes, and/or hyperlipemia, comprising the AGF as an active ingredient is disclosed. Furthermore, a method for treating or preventing obesity, diabetes, and/or hyperlipemia, comprising administering to a subject the AGF or a polynucleotide encoding the same is disclosed. Furthermore, use of the AGF or a polynucleotide encoding the same in the manufacture of an antiobesity agent, an antidiabetic agent, and/or a hypolipidemic agent is disclosed.
摘要翻译: 公开了包含血管生成素相关生长因子(AGF)的抗肥胖药,抗糖尿病药和/或降血脂剂或编码与多肽的活性成分相同的多核苷酸。 此外,公开了包含AGF作为活性成分的用于减轻肥胖,糖尿病和/或高脂血症的功能性食品或保健食品。 此外,公开了一种治疗或预防肥胖症,糖尿病和/或高脂血症的方法,其包括对受试者施用AGF或其编码该多核苷酸的多核苷酸。 此外,公开了在制造抗肥胖剂,抗糖尿病药和/或降血脂药中使用AGF或其编码该多核苷酸的多核苷酸。
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公开(公告)号:US20050175608A1
公开(公告)日:2005-08-11
申请号:US10500207
申请日:2002-12-26
申请人: Tadafumi Tamura , Masako Uchii , Toshio Suda , Ichiro Miki , Akira Tanaka
发明人: Tadafumi Tamura , Masako Uchii , Toshio Suda , Ichiro Miki , Akira Tanaka
IPC分类号: A61P19/02 , C07K16/22 , C07K16/24 , G01N33/68 , A61K39/395
CPC分类号: C07K16/22 , A61K2039/505 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/76
摘要: The invention provides an agent for preventing or treating arthritis, a cartilage protecting agent, a joint destruction inhibitor and a synovial membrane growth inhibitor comprising an anti-FGF-8 neutralizing antibody as an active ingredient, as well as a diagnostic agent of arthritis comprising an anti-FGF-8 antibody as an active ingredient and a method for judging arthritis using the antibody.
摘要翻译: 本发明提供了用于预防或治疗关节炎的药剂,软骨保护剂,关节破坏抑制剂和包含抗FGF-8中和抗体作为活性成分的滑膜生长抑制剂,以及包括 抗FGF-8抗体作为活性成分,以及使用该抗体判断关节炎的方法。
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