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公开(公告)号：US20200054792A1
公开(公告)日：2020-02-20
申请号：US15747663
申请日：2016-07-28
摘要： The present application relates to amphiphilic polypeptide materials, methods for making and using the same. Provided amphiphilic polypeptide materials are water-based and manufactured using all aqueous processing. Provided materials exhibit a capacity to encapsulate and store biologically active molecules or macromolecules. Such biologically active molecules or macromolecules retain their structure and the biological activity so that these biologically active molecules or macromolecules are not materially degraded, reduced, and/or inhibited by processing steps or exposure. Provided materials possess unique mechanical and structural properties, including size, density, moldability and machinability.
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公开(公告)号：US20130177608A1
公开(公告)日：2013-07-11
申请号：US13768615
申请日：2013-02-15
发明人： David L. Kaplan , Chunmei Li
IPC分类号： A61L27/22
CPC分类号： A61L27/227 , A61L27/24 , A61L27/30 , A61L27/446 , A61L27/46 , Y10T428/24999 , Y10T428/2933 , Y10T428/31768 , Y10T442/10
摘要： The present invention is directed to a method for forming an inorganic coating on a protein template. The method comprises contacting the template with an anionic polymer interface followed by an inorganic material for a sufficient period of time to allow mineralization of the inorganic material thus forming an inorganic coating on the template. Preferably, the coating is aligned.
摘要翻译： 本发明涉及一种在蛋白质模板上形成无机涂层的方法。 该方法包括使模板与阴离子聚合物界面接触，然后使无机材料接触足够的时间以允许无机材料的矿化，从而在模板上形成无机涂层。 优选地，将涂层对准。
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公开(公告)号：US20240325609A1
公开(公告)日：2024-10-03
申请号：US18482421
申请日：2023-10-06
CPC分类号： A61L27/56 , A61L27/227 , A61L27/46 , A61K9/5052 , A61L2300/62
摘要： The present application relates to amphiphilic polypeptide materials, methods for making and using the same. Provided amphiphilic polypeptide materials are water-based and manufactured using all aqueous processing. Provided materials exhibit a capacity to encapsulate and store biologically active molecules or macromolecules. Such biologically active molecules or macromolecules retain their structure and the biological activity so that these biologically active molecules or macromolecules are not materially degraded, reduced, and/or inhibited by processing steps or exposure. Provided materials possess unique mechanical and structural properties, including size, density, moldability and machinability.
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公开(公告)号：US20210381129A1
公开(公告)日：2021-12-09
申请号：US17309005
申请日：2019-10-10
摘要： In some embodiments, the present disclosure provides methods including the steps of (i) providing silk fibroin material comprising substantially amorphous structure, and (ii) applying at least one of elevated temperature and elevated pressure to the silk fibroin material to form a silk fibroin article, wherein the applying induces fusion between at least a portion of the silk fibroin and structural change of fibroin in the silk fibroin material. In some embodiments, the present disclosure also provides silk fibroin articles made in accordance with the methods disclosed herein.
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