Microspheres for controlled- or sustained-release delivery of therapeutics
    1.
    发明授权
    Microspheres for controlled- or sustained-release delivery of therapeutics 有权
    控制或持续释放治疗剂的微球

    公开(公告)号:US09381159B2

    公开(公告)日:2016-07-05

    申请号:US14362575

    申请日:2012-12-05

    摘要: A new microsphere formulation (composition) for controlled- or sustained-release delivery of therapeutic ingredient(s), mainly peptides and proteins not over 10K in molecular weight, comprises at least a therapeutic ingredient, a helping agent (such as PH sensitive agent whose solubility is a function of pH) and a biodegradable polymer. The therapeutic ingredient(s) and the helping agent are in the form of fine particles, less than 1O um in diameter, encapsulated in the polymer which forms the microsphere matrix. A method for preparing the composition comprises a step of in-situ precipitating the therapeutic ingredient(s) and the helping agent to the fine particles and successive steps for forming the microspheres. Such a microsphere formulation offers a well-controlled release profile for prolonged period and encapsulation efficiency over 95%.

    摘要翻译: 治疗成分(主要是分子量不超过10K的肽和蛋白质)的受控或持续释放递送的新微球制剂(组合物)至少包含治疗成分,助剂(例如PH敏感剂 溶解度是pH的函数)和可生物降解的聚合物。 治疗成分和助剂为直径小于10μm的细颗粒形式,包封在形成微球基质的聚合物中。 制备组合物的方法包括将治疗成分和辅助剂原位沉淀到细颗粒和用于形成微球的连续步骤的步骤。 这种微球制剂提供了良好控制的释放曲线,其延长的时间和包封效率超过95%。

    MICROSPHERES FOR CONTROLLED- OR SUSTAINED-RELEASE DELIVERY OF THERAPEUTICS
    2.
    发明申请
    MICROSPHERES FOR CONTROLLED- OR SUSTAINED-RELEASE DELIVERY OF THERAPEUTICS 有权
    用于控制或持续释放治疗药物的微生物

    公开(公告)号:US20140314853A1

    公开(公告)日:2014-10-23

    申请号:US14362575

    申请日:2012-12-05

    摘要: A new microsphere formulation (composition) for controlled- or sustained-release delivery of therapeutic ingredient(s), mainly peptides and proteins not over 10K in molecular weight, comprises at least a therapeutic ingredient, a helping agent (such as PH sensitive agent whose solubility is a function of pH) and a biodegradable polymer. The therapeutic ingredient(s) and the helping agent are in the form of fine particles, less than 1O um in diameter, encapsulated in the polymer which forms the microsphere matrix. A method for preparing the composition comprises a step of in-situ precipitating the therapeutic ingredient(s) and the helping agent to the fine particles and successive steps for forming the microspheres. Such a microsphere formulation offers a well-controlled release profile for prolonged period and encapsulation efficiency over 95%.

    摘要翻译: 治疗成分(主要是分子量不超过10K的肽和蛋白质)的受控或持续释放递送的新的微球制剂(组合物)至少包含治疗成分,助剂(例如PH敏感剂 溶解度是pH的函数)和可生物降解的聚合物。 治疗成分和助剂为直径小于10μm的细颗粒形式,包封在形成微球基质的聚合物中。 制备组合物的方法包括将治疗成分和辅助剂原位沉淀到细颗粒和用于形成微球的连续步骤的步骤。 这种微球制剂提供了良好控制的释放曲线,其延长的时间和包封效率超过95%。

    Multi-output antenna
    3.
    发明授权
    Multi-output antenna 有权
    多输出天线

    公开(公告)号:US09537223B2

    公开(公告)日:2017-01-03

    申请号:US14234951

    申请日:2012-07-26

    申请人: Peter Hall Zhenhua Hu

    发明人: Peter Hall Zhenhua Hu

    摘要: A reconfigurable multi-output antenna (16) is disclosed comprising: one or more radiating elements (12, 14), at least two matching circuits (42, 44, 50, 52) coupled to the or each radiating element (12, 14) via e.g. a splitter (30, 32) or a duplexer; and wherein each matching circuit (42, 44, 50, 52) is associated with a separate port (38, 40, 46, 48) arranged to drive a separate resonant frequency so that the or each radiating element (12, 14) is operable to provide multiple outputs simultaneously. The resonant frequency of each output is independently controllable by each matching circuit, with good isolation with each other port, thereby offering very wide operating frequency range with simultaneous multi-independent output operations. Also described is a multi-output antenna control module for coupling to one or more radiating elements, an antenna structure and an antenna interface module. A reconfigurable multi-output antenna is disclosed comprising: one or more radiating.

    摘要翻译: 公开了一种可重新配置的多输出天线(16),包括:一个或多个辐射元件(12,14),耦合到或每个辐射元件(12,14)的至少两个匹配电路(42,44,50,52) 通过例如 分离器(30,32)或双工器; 并且其中每个匹配电路(42,44,50,52)与被布置成驱动单独谐振频率的单独端口(38,40,46,48)相关联,以使得所述或每个辐射元件(12,14)可操作 同时提供多个输出。 每个输出的谐振频率可由每个匹配电路独立控制,每个匹配电路具有良好的隔离性,从而提供非常宽的工作频率范围,同时具有多独立输出操作。 还描述了一种用于耦合到一个或多个辐射元件,天线结构和天线接口模块的多输出天线控制模块。 公开了一种可重新配置的多输出天线,包括:一个或多个辐射。

    Cold-launch device and method using the same
    4.
    发明授权
    Cold-launch device and method using the same 有权
    冷启动装置及其使用方法

    公开(公告)号:US08950704B2

    公开(公告)日:2015-02-10

    申请号:US13036032

    申请日:2011-02-28

    IPC分类号: B64F1/02 B64F1/06

    CPC分类号: B64F1/06

    摘要: A cold-launch device, including a high-energy gas resource, a gas cylinder, a control valve, a gas-liquid mixing cylinder having a cylinder body, the high-energy gas resource is connected to the gas cylinder whereby supplying energy thereto, and the gas cylinder is connected to an terminal of the gas-liquid mixing cylinder via the control valve and a connecting pipe.

    摘要翻译: 一种冷启动装置,包括高能气体资源,气瓶,控制阀,具有缸体的气液混合缸,高能气体源连接到气缸,从而向其供应能量, 并且气瓶经由控制阀和连接管连接到气液混合缸的端子。

    Resource manager for managing the sharing of resources among multiple workloads in a distributed computing environment
    5.
    发明申请
    Resource manager for managing the sharing of resources among multiple workloads in a distributed computing environment 有权
    用于在分布式计算环境中管理多个工作负载之间的资源共享的资源管理器

    公开(公告)号:US20080155100A1

    公开(公告)日:2008-06-26

    申请号:US11614810

    申请日:2006-12-21

    IPC分类号: G06F15/173

    摘要: A resource manager for managing the sharing of resources among multiple workloads in a distributed computing environment. The resource manager comprises an allocation service component which applies a resource allocation policy to determine whether the requested resources may be allocated. The resource manager also comprises a dynamic provisioning service component which applies a reprovisioning policy to modify the make-up of the resources in response to unsatisfied resource requests. The allocation of resources to consumers may be determined in accordance with the resource ownership and share rights of the consumer on behalf of which the application or workload is being demanded.

    摘要翻译: 用于在分布式计算环境中管理多个工作负载之间的资源共享的资源管理器。 资源管理器包括分配服务组件,该分配服务组件应用资源分配策略来确定是否可以分配所请求的资源。 资源管理器还包括动态供应服务组件,其应用重新配置策略以响应于不满足的资源请求修改资源的组成。 消费者资源分配可以根据消费者的资源所有权和共享权来确定,代表需要应用或工作量的消费者。

    MULTI-OUTPUT ANTENNA
    9.
    发明申请
    MULTI-OUTPUT ANTENNA 有权
    多输出天线

    公开(公告)号:US20140159971A1

    公开(公告)日:2014-06-12

    申请号:US14234951

    申请日:2012-07-26

    申请人: Peter Hall Zhenhua Hu

    发明人: Peter Hall Zhenhua Hu

    IPC分类号: H01Q21/00

    摘要: A reconfigurable multi-output antenna (16) is disclosed comprising: one or more radiating elements (12, 14), at least two matching circuits (42, 44, 50, 52) coupled to the or each radiating element (12, 14) via e.g. a splitter (30, 32) or a diplxer; and wherein each matching circuit (42, 44, 50, 52) is associated with a separate port (38, 40, 46, 48) arranged to drive a separate resonant frequency so that the or each radiating element (12, 14) is operable to provide multiple outputs simultaneously. The resonant frequency of each output is independently controllable by each matching circuit, with good isolation with each other port, thereby offering very wide operating frequency range with simultaneous multi-independent output operations. Also described is a multi-output antenna control module for coupling to one or more radiating elements, an antenna structure and an antenna interface module. A reconfigurable multi-output antenna is disclosed comprising: one or more radiating

    摘要翻译: 公开了一种可重新配置的多输出天线(16),包括:一个或多个辐射元件(12,14),耦合到或每个辐射元件(12,14)的至少两个匹配电路(42,44,50,52) 通过例如 一个分离器(30,32)或一个转换器; 并且其中每个匹配电路(42,44,50,52)与被布置成驱动单独谐振频率的单独端口(38,40,46,48)相关联,以使得所述或每个辐射元件(12,14)可操作 同时提供多个输出。 每个输出的谐振频率可由每个匹配电路独立控制,每个匹配电路具有良好的隔离性,从而提供非常宽的工作频率范围,同时具有多独立输出操作。 还描述了一种用于耦合到一个或多个辐射元件,天线结构和天线接口模块的多输出天线控制模块。 公开了一种可重新配置的多输出天线,包括:一个或多个辐射

    Hydraulic jack and a hydraulic circuit for such a hydraulic jack

    公开(公告)号:US06546725B2

    公开(公告)日:2003-04-15

    申请号:US09740743

    申请日:2000-12-19

    IPC分类号: F16D3102

    CPC分类号: B66F3/24

    摘要: A continuously auto lifting and lowering hydraulic jack comprises a base, an oil pump, working oil cylinder, a piston, an oil box, an accumulator, a two-position and two-way valve, a dual-controlling check, a pressure-set check and other checks. The two-position and two-way valve, the dual-controlling check and the pressure-set check are arranged in a straight line; a valve bore is formed in the base to serve as a common valve bore for the two-position and two-way valve, the dual-controlling check and the pressure-set check. Valve members of the two-position and two-way valve, the dual-controlling check and the pressure-set check are disposed sequentially in the valve bore in series; a tappet is positioned between the two-position and two-way valve and the dual-controlling check; and another tappet is positioned between the dual-controlling check and the pressure-set check. Also disclosed is a hydraulic circuit for the hydraulic jack.