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公开(公告)号:US20180078746A1
公开(公告)日:2018-03-22
申请号:US15564105
申请日:2016-04-04
发明人: Philippe CINQUIN , Dominique SCHNEIDER , Max MAURIN , Donald MARTIN , Sarra EL ICHI , Abdelkader ZEBDA , Jean-Pierre ALCARAZ , Fabian RECHE , Patrick TUVIGNON , Jacques THELU , Audrey LE GOUELLEC , Bertrand TOUSSAINT
CPC分类号: A61M31/002 , A61B5/6871 , A61B5/6873 , A61K35/747 , A61K38/28 , A61L31/042 , A61L31/14 , A61L31/146 , A61L31/16 , A61L2300/43 , A61L2400/18 , A61M25/04 , A61M2210/1053 , A61M2210/1057 , A61M2210/106 , B01D69/144 , Y02A50/473
摘要: The device, that can be implanted in the intestinal cavity, comprises a reactor comprising a semi-permeable or porous membrane or coating linked to a element for attachment to an intestinal or gastric wall. The reactor can be in the form of a ribbon, a structure having more than two faces or an open structure delimiting a lumen, comprising, or formed from, a semi-permeable or porous membrane. The reactor can also delimit, at least partially with the semi-permeable or porous membrane of same, a closed inner space. The reactor can comprise or carry enzymes or micro-organisms, in particular bacteria or yeast. The reactor is used for generating a chemical reaction with one or more molecules present in the intestine, or for producing one or more biologically active molecules. It can, in particular, be used for consuming sugars, disaccharides and simple sugars or producing essential amino acids or other molecules having a positive effect on the health.
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公开(公告)号:US20170081626A1
公开(公告)日:2017-03-23
申请号:US15126236
申请日:2015-03-23
CPC分类号: C12M29/04 , B29C41/003 , B29C65/4805 , B29K2005/00 , B29K2995/0068 , B29L2031/34 , B29L2031/755 , G01N27/3271 , H01M4/8605 , H01M4/8663 , H01M4/8673 , H01M4/8896 , H01M4/9008 , H01M4/9083 , H01M8/16 , H01M2250/30 , Y02B90/18 , Y02E60/527
摘要: The invention concerns a bioreactor obtained by compressing a mixture of an enzyme, a conductor and chitosan. The conductor can consist of carbon nanotubes. This bioreactor can be produced according to the following steps: preparing a mixture of powders in which the proportion of enzyme powder relative to a carbon nanotube powder is of the order of 50/50 by weight; preparing a viscous solution of chitosan in a ratio of 5 to 15 (in mg) of chitosan to 0.75 to 1.25 (in ml) of acetic acid diluted to 0.4 to 0.6% by volume in water; adding the viscous chitosan to the mixture of powders in a proportion be weight of 3 to 5 of powder to 5 to 10 of chitosan; carrying out a first compression followed by light grinding; carrying out a second compression to produce a pellet; and drying at ambient temperature.
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