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    RETENTIVE DEVICES FOR GASTROINTESTINAL TRACT
    2.
    发明公开
    RETENTIVE DEVICES FOR GASTROINTESTINAL TRACT 审中-公开

    公开(公告)号：US20240139480A1

    公开(公告)日：2024-05-02

    申请号：US18548915

    申请日：2022-03-02

    申请人： Teva Pharmaceutical Industries Ltd.

    发明人： Avshalom BEN MENACHEM ,  Ilan ZALIT

    IPC分类号： A61M31/00

    CPC分类号： A61M31/002 ,  A61M2210/1053 ,  A61M2210/106

    摘要： A device for temporary residence at a predetermined location of the gastrointestinal tract of a subject is described. The device transfers from a closed configuration into an expanded configuration. The device is retained at the predetermined location and transfers from the expanded configuration into an emptying configuration in which the device moves past the predetermined location. The device enables localized medical methods in the gastrointestinal tract of the subject.

    THERAPEUTIC AGENT PREPARATIONS FOR DELIVERY INTO A LUMEN OF THE INTESTINAL TRACT USING A SWALLOWABLE DRUG DELIVERY DEVICE
    9.
    发明申请
    THERAPEUTIC AGENT PREPARATIONS FOR DELIVERY INTO A LUMEN OF THE INTESTINAL TRACT USING A SWALLOWABLE DRUG DELIVERY DEVICE 有权

    公开(公告)号：US20130177527A1

    公开(公告)日：2013-07-11

    申请号：US13538903

    申请日：2012-06-29

    申请人： Mir Imran

    发明人： Mir Imran

    IPC分类号： A61K9/00 ,  A61M5/00 ,  A61M25/10

    CPC分类号： A61K9/0053 ,  A61K9/4808 ,  A61K31/155 ,  A61K38/21 ,  A61M5/00 ,  A61M25/10 ,  A61M31/002 ,  A61M2210/106

    摘要： Embodiments of the invention provide swallowable devices, preparations and methods for delivering drugs and other therapeutic agents within the GI tract. Many embodiments provide a swallowable device for delivering the agents. Particular embodiments provide a swallowable device such as a capsule for delivering drugs into the intestinal wall or other GI lumen. Embodiments also provide various drug preparations that are configured to be contained within the capsule, advanced from the capsule into the intestinal wall and degrade to release the drug into the bloodstream to produce a therapeutic effect. The preparation can be operably coupled to delivery means having a first configuration where the preparation is contained in the capsule and a second configuration where the preparation is advanced out of the capsule into the intestinal wall. Embodiments of the invention are particularly useful for the delivery of drugs which are poorly absorbed, tolerated and/or degraded within the GI tract.

    METHOD FOR COMBINED GASTROINTESTIONAL FEEDING AND ASPIRATION
    10.
    发明申请
    METHOD FOR COMBINED GASTROINTESTIONAL FEEDING AND ASPIRATION 审中-公开
    用于组合输送和吸收的方法

    公开(公告)号：US20120283627A1

    公开(公告)日：2012-11-08

    申请号：US13102934

    申请日：2011-05-06

    申请人： Gerald Moss

    发明人： Gerald Moss

    IPC分类号： A61M1/00 ,  A61M31/00

    CPC分类号： A61J15/0003 ,  A61J15/0069 ,  A61J15/0073 ,  A61J15/0076 ,  A61J15/0092 ,  A61J2200/76 ,  A61M1/0058 ,  A61M1/0084 ,  A61M2210/1053 ,  A61M2210/106

    摘要： A method is provided in which continuous suction alternately removes fluid through an aspiration lumen from the stomach and adjacent small intestine and returns the fluid with gravity a short distance downstream. The only aspirate permanently discarded is that volume of inflow to the feeding site that momentarily exceeded peristaltic outflow. Feeding is also continuous, which allows for a smaller and more comfortable feeding tube. This frequent aspiration and feeding serves to provide the maximum safe nutrition, while preventing overfeeding and its associated risks of intestinal distention.

    摘要翻译： 提供了一种方法，其中连续抽吸通过来自胃和相邻小肠的抽吸腔交替地去除流体，并使重力在下游短距离返回流体。 永久丢弃的唯一的吸入物是瞬间超过蠕动流出物的进料量。 进料也是连续的，这允许更小和更舒适的进料管。 这种频繁的抽吸和喂养有助于提供最大的安全营养，同时防止过量喂养及其相关的肠膨胀风险。