公开(公告)号：US11766475B2

公开(公告)日：2023-09-26

申请号：US17207948

申请日：2021-03-22

Applicant: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED

Inventor： Roy Curtiss, III ,  Soo-Young Wanda

IPC: A61K39/02 ,  A61K39/112 ,  A61K39/205 ,  C07K14/205 ,  C12N1/36 ,  C12N15/74 ,  A61K39/00

CPC classification number: A61K39/0275 ,  A61K39/105 ,  A61K39/205 ,  C07K14/205 ,  C12N1/36 ,  C12N15/74 ,  A61K2039/522 ,  A61K2039/523 ,  A61K2039/58 ,  A61K2039/70

Abstract: Described herein are compositions and methods for making and using recombinant bacteria that are capable of regulated attenuation, regulated expression of one or more antigens of interest, and/or N-glycan modification of secreted/surface antigens.

公开(公告)号：US20200009240A1

公开(公告)日：2020-01-09

申请号：US16480904

申请日：2018-01-26

Applicant: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED

Inventor： Roy Curtiss, III ,  Soo-Young Wanda

IPC: A61K39/112 ,  A61K39/02 ,  A61K39/205 ,  C07K14/205 ,  C12N1/36 ,  C12N15/74

Abstract: Described herein are compositions and methods for making and using recombinant bacteria that are capable of regulated attenuation, regulated expression of one or more antigens of interest, and/or N-glycan modification of secreted/surface antigens.

公开(公告)号：US20210283235A1

公开(公告)日：2021-09-16

申请号：US17207948

申请日：2021-03-22

Applicant: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED

Inventor： Roy Curtiss, III ,  Soo-Young Wanda

IPC: A61K39/112 ,  A61K39/02 ,  A61K39/205 ,  C07K14/205 ,  C12N1/36 ,  C12N15/74

Abstract: Described herein are compositions and methods for making and using recombinant bacteria that are capable of regulated attenuation, regulated expression of one or more antigens of interest, and/or N-glycan modification of secreted/surface antigens.

公开(公告)号：US11000583B2

公开(公告)日：2021-05-11

申请号：US16480904

申请日：2018-01-26

Applicant: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED

Inventor： Roy Curtiss, III ,  Soo-Young Wanda

IPC: A61K39/02 ,  A61K39/112 ,  A61K39/205 ,  C07K14/205 ,  C12N1/36 ,  C12N15/74 ,  A61K39/00

Abstract: Described herein are compositions and methods for making and using recombinant bacteria that are capable of regulated attenuation, regulated expression of one or more antigens of interest, and/or N-glycan modification of secreted/surface antigens.