公开(公告)号：US11458224B2

公开(公告)日：2022-10-04

申请号：US15449742

申请日：2017-03-03

申请人： UNIVERSITY OF PITTSBURGH—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION

发明人： Bryan Brown ,  Michael Buckenmeyer ,  Aleksandar Rajkovic ,  Yonghyun Shin

IPC分类号： A61L27/38 ,  A61L27/52 ,  A61L27/36 ,  C12N5/075

摘要： The present invention relates to an ovarian-derived hydrogel material, which can be useful for three-dimensional in vitro culturing of cells, cell therapy, fertility preservation, drug delivery, site-specific remodeling and repair of damaged tissue, and/or diagnostic kits.

公开(公告)号：US12064532B2

公开(公告)日：2024-08-20

申请号：US17872467

申请日：2022-07-25

申请人： UNIVERSITY OF PITTSBURGH—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION

发明人： Bryan Brown ,  Michael Buckenmeyer ,  Aleksandar Rajkovic ,  Yonghyun Shin

IPC分类号： A61L27/38 ,  A61L27/36 ,  A61L27/52 ,  C12N5/075

CPC分类号： A61L27/3804 ,  A61L27/3604 ,  A61L27/3687 ,  A61L27/3691 ,  A61L27/52 ,  C12N5/0609 ,  A61L2400/06 ,  A61L2430/40 ,  C12N2500/84

摘要： The present invention relates to an ovarian-derived hydrogel material, which can be useful for three-dimensional in vitro culturing of cells, cell therapy, fertility preservation, drug delivery, site-specific remodeling and repair of damaged tissue, and/or diagnostic kits.

公开(公告)号：US20220323648A1

公开(公告)日：2022-10-13

申请号：US17762858

申请日：2020-09-30

申请人： University of Pittsburgh - Of the Commonwealth System of Higher Education ,  RENERVA, LLC

发明人： Lorenzo Soletti ,  Bryan Brown ,  Josh Bowman ,  Nicole Cwalina ,  Brandon Burger ,  J. Christopher Flaherty

IPC分类号： A61L27/36

摘要： Systems, devices, and methods for treating a nerve injury in a patient are provided herein. The system includes an extracellular matrix, a neutralizing element, and a reconstituting element. The extracellular matrix is configured to promote and/or sustain the growth of tissue and/or associated tissue properties proximate the nerve injury.

公开(公告)号：US20220395612A1

公开(公告)日：2022-12-15

申请号：US17872467

申请日：2022-07-25

申请人： UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION

发明人： Bryan Brown ,  Michael Buckenmeyer ,  Aleksandar Rajkovic ,  Yonghyun Shin

IPC分类号： A61L27/38 ,  A61L27/52 ,  A61L27/36 ,  C12N5/075

摘要： The present invention relates to an ovarian-derived hydrogel material, which can be useful for three-dimensional in vitro culturing of cells, cell therapy, fertility preservation, drug delivery, site-specific remodeling and repair of damaged tissue, and/or diagnostic kits.

公开(公告)号：US20170252485A1

公开(公告)日：2017-09-07

申请号：US15449742

申请日：2017-03-03

申请人： UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION

发明人： Bryan Brown ,  Michael Buckenmeyer ,  Aleksandar Rajkovic ,  Yonghyun Shin

IPC分类号： A61L27/38 ,  A61L27/36 ,  C12N5/075 ,  A61L27/52

CPC分类号： A61L27/3804 ,  A61L27/3604 ,  A61L27/3687 ,  A61L27/3691 ,  A61L27/52 ,  A61L2400/06 ,  A61L2430/40 ,  C12N5/0609 ,  C12N5/0682 ,  C12N2500/84 ,  C12N2533/90

摘要： The present invention relates to an ovarian-derived hydrogel material, which can be useful for three-dimensional in vitro culturing of cells, cell therapy, fertility preservation, drug delivery, site-specific remodeling and repair of damaged tissue, and/or diagnostic kits.