专利检索 ap:("UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION" OR "UNIVERSITY OF CINCINNATI") AND inv:"VESSELIN SHANOV" 第 1 页

1.

发明公开
MG ALLOY MESH REINFORCED POLYMER/ECM HYBRID SCAFFOLDS FOR CRITICAL-SIZED BONE DEFECT REGENERATION 审中-公开

公开(公告)号：US20240181126A1

公开(公告)日：2024-06-06

申请号：US18409074

申请日：2024-01-10

申请人： UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION , UNIVERSITY OF CINCINNATI

发明人： WILLIAM R. WAGNER , SANG-HO YE , YINGQI CHEN , VESSELIN SHANOV

IPC分类号： A61L27/04 , A61L27/34 , A61L27/36 , A61L27/44 , A61L27/56 , A61L27/58

CPC分类号： A61L27/047 , A61L27/34 , A61L27/3608 , A61L27/3687 , A61L27/3691 , A61L27/44 , A61L27/56 , A61L27/58 , A61L2400/12 , A61L2420/02 , A61L2430/02

摘要： The invention relates to biomimetic, biodegradable composites including a magnesium (Mg) alloy mesh and a polymer/extracellular matrix (ECM). These hybrid composites, more particularly, are useful for the fabrication of medical implant devices, e.g., scaffolds, and are effective for bone regeneration. The fabrication process includes creating the Mg alloy mesh, and concurrently electrospinning the polymer and electrospraying the ECM onto the mesh.