公开(公告)号：US20210324011A1

公开(公告)日：2021-10-21

申请号：US17285057

申请日：2019-10-24

Applicant: UNIVERSITY OF WASHINGTON

Inventor： Hao SHEN ,  Jorge FALLAS ,  David BAKER

IPC: C07K14/00 ,  C07K1/00

Abstract: Disclosed herein are polypeptides having the amino acid sequence that is at least 50%, 55%, 60%, 65%, 70%, 75%, 80%, 85%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to the full length of the amino acid sequence selected from the group consisting of SEQ ID NO: 1-33 and 36, wherein the polypeptides include at least 50%, 55%, 60%, 65%, 70%, 75%, 80%, 85%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% of the identified interface residues, and wherein the polypeptides are capable of end-to-end homo-polymerization, homo-polymers of the polypeptides, and related capping and anchor proteins to facilitate homo-polymer formation.