专利检索 ap:("UNM RAINFOREST INNOVATIONS" OR "THE JOHNS HOPKINS UNIVERSITY" OR "VAXINE PTY LTD.") AND inv:"Lucia Jelinkova" 第 1 页

1.

发明申请
MALARIA IMMUNOGEN AND METHODS FOR USING SAME 有权

公开(公告)号：US20220280632A1

公开(公告)日：2022-09-08

申请号：US17628640

申请日：2020-07-24

申请人： Bryce CHACKERIAN , David S. PEABODY , Nikolai PETROVSKY , Lucia JELINKOVA , Fidel ZAVALA , UNM RAINFOREST INNOVATIONS , THE JOHNS HOPKINS UNIVERSITY , VAXINE PTY LTD.

发明人： Bryce Chackerian , David S. Peabody , Nikolai Petrovsky , Lucia Jelinkova , Fidel Zavala

IPC分类号： A61K39/12 , C07K14/005 , C12N7/00 , A61P33/06

摘要： An immunogen useful for treating malaria generally includes an immunogenic carrier and an antigenic malaria circumsporozoite protein (CSP) peptide that includes the peptide NPDPNANPNVDPNAN (amino acids 5-19 of SEQ ID NO:1) linked to the immunogenic carrier. The immunogen may be administered to a subject having or at risk of having malaria.

2.

发明申请
MALARIA IMMUNOGEN AND METHODS FOR USING SAME 有权

公开(公告)号：US20230102159A1

公开(公告)日：2023-03-30

申请号：US17953712

申请日：2022-09-27

申请人： UNM RAINFOREST INNOVATIONS , THE JOHNS HOPKINS UNIVERSITY , VAXINE PTY LTD.

发明人： Bryce C. Chackerian , Fidel P. Zavala , David S. Peabody , Nikolai Petrovsky , Lucia Jelinkova

IPC分类号： A61K39/015 , A61P33/06 , C12N15/63

摘要： An immunogen useful for treating malaria generally includes an immunogenic carrier and an antigenic malaria circumsporozoite protein (CSP) peptide that includes the peptide NANPNVDPNANPNVD (SEQ ID NO:2) linked to the immunogenic carrier. The immunogen may be administered to a subject having or at risk of having malaria. Alternatively, the immunogen may be administered to an individual having or at risk of having Plasmodium falciparum blood stage parasitemia. In some cases, the immunogen can be administered in combination with another therapeutic agent for treating malaria of Plasmodium falciparum blood stage parasitemia.