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    2-hydroxy - 3 - (1-hydroxyethyl)-5-carboxy - 3,4 - dihydro-2h-pyran-4-acetic acid 4,5-dimethyl ester, 3-methanesulfonate
    1.
    发明授权
    2-hydroxy - 3 - (1-hydroxyethyl)-5-carboxy - 3,4 - dihydro-2h-pyran-4-acetic acid 4,5-dimethyl ester, 3-methanesulfonate 失效
    2-羟基-3-（1-羟基乙基）-5-羧酸-3,4-二氢-2H-吡喃-4-乙酸4,5-二甲酯3-甲磺酸酯

    公开(公告)号：US3770777A

    公开(公告)日：1973-11-06

    申请号：US3770777D

    申请日：1972-04-12

    申请人： UPJOHN CO

    发明人： KELLY R

    IPC分类号： C07D307/93 ,  C07D317/70 ,  C25B3/02 ,  C07D7/14

    CPC分类号： C07D307/93 ,  C07D317/70 ,  C25B3/02

    摘要： WHEREIN R AND R3 ARE ALKYL OF 1 TO 8 CARBON ATOMS, INCLUSIVE, WHEREIN R1 IS ALKYL OF 1 TO 4 CARBON ATOMS, INCLUSIVE, AND WHEREIN R2 IS SELECTED FROM THE GROUP CONSISTING OF HYDROGEN AND ALKYL OF 1 TO 4 CARBON ATOMS, INCLUSICVE IS CARRIED OUT BY A MULTI-STEP PROCESS STARTING FROM CYCLOPENTADIENE. COMPOUNDS OF FORMULA XIV HAVE VIRUCIDAL AND HYPOTENSICVE ACTIVITY AND CAN BE USED AS HYPOTENSIVE AGENTS IN MAMMALS (U.S.PAT.3,033,877) OR AS VIRUCIDAL AGENTS TO DECONTAMINATE SURGICAL INSTRUMENTS, HOSPITAL WALLS, SWIMMING POOLS, OR CAN BE USED FOR NASAL WASHES IN MAMMALS.

    2H-PYRAN

    2-R1,3-(O=CH-),4-(R-OOC-CH(-R2)-),5-(R3-OOC-)-3,4-DIHYDRO-

    A TOTAL SYNTHESIS OF ELENOLIC ACID, FORMULA XIV (R AND R2 ARE HYDROGEN, R1 AND R3 ARE METHYL) AND THE ANALOGS THEREOF, OF FORMULA XIV:

    Intermediate in the total synthesis of elenolic acid
    4.
    发明授权
    Intermediate in the total synthesis of elenolic acid 失效
    中间体在乙醛酸的总合成

    公开(公告)号：US3786068A

    公开(公告)日：1974-01-15

    申请号：US3786068D

    申请日：1972-04-12

    申请人： UPJOHN CO

    发明人： KELLY R

    IPC分类号： C07D307/93 ,  C07D317/70 ,  C25B3/02 ,  C07D13/10

    CPC分类号： C25B3/02 ,  C07D307/93 ,  C07D317/70

    摘要： A COMPOUND OF THE FORMULA:

    2-R4,2-R5,5-R1,8-(R2-CH(-COO-R)-)-3A,4,7,7A-TETRAHYDRO-

    4,7-METHANO-1,3-BENZODIOXOLE

    WHEREIN R IS ALKYL OF 1 TO 8 CARBON ATOMS, INCLUSIVE, R1 IS ALKYL OF 1 TO 4 CARBON ATOMS, R2 IS HYDROGEN OR ALKYL OF 1 TO 4 CARBON ATOMS, AND R4 AND R5 ARE HYDROGEN, ALKYL OF 1 TO 4 CARBON ATOMS, INCLUSIVE OR PHENYL, WITH THE PROVISO THAT ONLY ONE OF R4 AND R5 IS PHENYL, IS PRODUCED IN A MULTISTEP REACTION. THE COMPOUND IS AN INTERMEDIATE FOR ELENOLIC ACID.