METHOD FOR SYNTHESIZING AN N-UNSUBSTITUTED OR N-SUBSTITUTED AZIRIDINE
    3.
    发明申请
    METHOD FOR SYNTHESIZING AN N-UNSUBSTITUTED OR N-SUBSTITUTED AZIRIDINE 审中-公开
    合成N-取代或N-取代的AZIRIDINE的方法

    公开(公告)号:US20100191000A1

    公开(公告)日:2010-07-29

    申请号:US12665509

    申请日:2008-06-18

    IPC分类号: C07D203/08 C25B3/02

    CPC分类号: C07D203/08 C07D203/02

    摘要: Process for preparing an N-unsubstituted or N-substituted aziridine of the formula which comprises reacting an olefin of the formula I where R1 to R5 are each, independently of one another, hydrogen, a linear or branched alkyl radical having from 1 to 16 carbon atoms, a hydroxyalkyl radical having from 1 to 4 carbon atoms, a cycloalkyl radical having from 5 to 7 carbon atoms, a benzyl or phenyl radical which in each case may be substituted in the o, m or p position of the phenyl radical by methoxy, hydroxy, chlorine or alkyl radicals having from 1 to 4 carbon atoms and the radical R1 or R2 together with the radical R3 or R4 may be closed to form a 5- to 12-membered ring or the radicals R1 and R2 may be closed to form a 5- to 12-membered ring, with ammonia or a primary amine of the formula R5NH2 in the presence of iodine or bromine.

    摘要翻译: 制备下式的N-未取代的或N-取代的氮丙啶的方法,其包括使式I的烯烃(其中R 1至R 5)彼此独立地彼此独立地为氢,具有1至16个碳原子的直链或支链烷基 原子,具有1至4个碳原子的羟基烷基,具有5至7个碳原子的环烷基,苄基或苯基,其在每种情况下可以在苯基的o,m或p位置被甲氧基取代 ,羟基,氯或具有1至4个碳原子的烷基和基团R 1或R 2与基团R 3或R 4一起可以封闭以形成5至12元环,或者基团R 1和R 2可以被封闭 在碘或溴的存在下与氨或式R 5 NH 2的伯胺形成5-至12元环。