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公开(公告)号：US20130012432A1
公开(公告)日：2013-01-10
申请号：US13580042
申请日：2011-02-28
申请人： Kilian Waldemar Conde-Frieboes , Jane Spetzler , Ulrich Sensfuss , Birgitte Schjellerup Wulff , Henning Thoegersen , Jens Christian Norrild
发明人： Kilian Waldemar Conde-Frieboes , Jane Spetzler , Ulrich Sensfuss , Birgitte Schjellerup Wulff , Henning Thoegersen , Jens Christian Norrild
IPC分类号： A61K38/12 , A61P3/10 , A61P3/04 , A61P3/00 , A61P35/00 , A61P15/00 , A61P9/12 , A61P1/16 , A61P19/08 , A61P19/02 , A61P29/00 , A61P37/06 , C07K7/56 , A61P9/00
CPC分类号： C07K14/68
摘要： The present invention relates to novel peptide compounds which are effective in modulating one or more melanocortin receptor types, to the use of the compounds in therapy, to methods of treatment comprising administration of the compounds to patients in need thereof, and to the use of the compounds in the manufacture of medicaments. The compounds of the invention are of particular interest in relation to the treatment of obesity as well as a variety of diseases or conditions associated with obesity.
摘要翻译： 本发明涉及有效调节一种或多种黑皮质素受体类型的新型肽化合物，治疗中化合物的用途，包括向有需要的患者施用化合物的治疗方法，以及使用 药物制造中的化合物。 本发明的化合物在治疗肥胖以及与肥胖相关的各种疾病或病症方面特别有意义。
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公开(公告)号：US20090203581A1
公开(公告)日：2009-08-13
申请号：US11995351
申请日：2006-07-07
申请人： Ulrich Sensfuss , Leif Christensen , Jane Spetzler , Kilian Waldemar Conde Frieboes , Henning Thogersen
发明人： Ulrich Sensfuss , Leif Christensen , Jane Spetzler , Kilian Waldemar Conde Frieboes , Henning Thogersen
CPC分类号： C07K14/685 , A61K47/542 , A61K47/545
摘要： The present invention relates to novel peptide compounds which are effective in modulating one or more melanocortin receptor types, to the use of the compounds in therapy, to methods of treatment comprising administration of the compounds to patients in need thereof, and to the use of the compounds in the manufacture of medicaments. The compounds of the invention are of particular interest in relation to the treatment of obesity as well as a variety of diseases or conditions associated with obesity.
摘要翻译： 本发明涉及有效调节一种或多种黑皮质素受体类型的新型肽化合物，治疗中化合物的用途，包括向有需要的患者施用化合物的治疗方法，以及使用 药物制造中的化合物。 本发明的化合物在治疗肥胖以及与肥胖相关的各种疾病或病症方面特别有意义。
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公开(公告)号：US20100016237A1
公开(公告)日：2010-01-21
申请号：US12521906
申请日：2008-01-17
CPC分类号： C07K14/68
摘要： The present invention relates to novel peptide compounds which are effective in modulating one or more melanocortin receptor types, to the use of the compounds in therapy, to methods of treatment comprising administration of the compounds to patients in need thereof, and to the use of the compounds in the manufacture of medicaments. The compounds of the invention are of particular interest in relation to the treatment of obesity as well as a variety of diseases or conditions associated with obesity.
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公开(公告)号：US20100173835A1
公开(公告)日：2010-07-08
申请号：US12626188
申请日：2009-11-25
CPC分类号： C07K14/685 , A61K47/542 , A61K47/545
摘要： The present invention relates to novel peptide compounds which are effective in modulating one or more melanocortin receptor types, to the use of the compounds in therapy, to methods of treatment comprising administration of the compounds to patients in need thereof, and to the use of the compounds in the manufacture of medicaments. The compounds of the invention are of particular interest in relation to the treatment of obesity as well as a variety of diseases or conditions associated with obesity.
摘要翻译： 本发明涉及有效调节一种或多种黑皮质素受体类型的新型肽化合物，治疗中化合物的用途，包括向有需要的患者施用化合物的治疗方法，以及使用 药物制造中的化合物。 本发明的化合物在治疗肥胖以及与肥胖相关的各种疾病或病症方面特别有意义。
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公开(公告)号：US07541430B2
公开(公告)日：2009-06-02
申请号：US11268268
申请日：2005-11-07
申请人： Ulrich Sensfuss , Kilian Waldemar Conde Frieboes , Leif Christensen , Ingrid Vivika Petterson , Thomas Kruse Hansen , Michael Ankersen , Kjeld Madsen
发明人： Ulrich Sensfuss , Kilian Waldemar Conde Frieboes , Leif Christensen , Ingrid Vivika Petterson , Thomas Kruse Hansen , Michael Ankersen , Kjeld Madsen
IPC分类号： A61K38/10
摘要： Novel cyclic and linear peptides of the formula R1—X—X1—X2—X3—X4—X5—X6—X7—X8—X9—X10—X11—R2 are useful in the treatment of obesity are provided.
摘要翻译： 式R1-X-X1-X2-X3-X4-X5-X6-X7-X8-X9-X10-X11-R2的新型环状和线性肽可用于治疗肥胖症。
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公开(公告)号：US20110098213A1
公开(公告)日：2011-04-28
申请号：US11666794
申请日：2005-11-04
IPC分类号： A61K38/12 , C07K7/56 , C07K7/08 , A61K38/10 , A61P3/04 , A61P25/00 , A61P9/10 , A61P9/12 , A61P3/06 , A61P9/00 , A61P19/02 , A61P35/00 , A61P1/16
摘要： The present invention relates to novel peptide compounds which are effective in modulating one or more melanocortin receptor types, to the use of the compounds in therapy, to methods of treatment comprising administration of the compounds to patients in need thereof, and to the use of the compounds in the manufacture of medicaments. The compounds of the invention are of particular interest in relation to the treatment of obesity as well as a variety of diseases or conditions associated with obesity.
摘要翻译： 本发明涉及有效调节一种或多种黑皮质素受体类型的新型肽化合物，治疗中化合物的用途，包括向有需要的患者施用化合物的治疗方法，以及使用 药物制造中的化合物。 本发明的化合物在治疗肥胖以及与肥胖相关的各种疾病或病症方面特别有意义。
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公开(公告)号：US20120021973A1
公开(公告)日：2012-01-26
申请号：US13130839
申请日：2009-11-24
IPC分类号： A61K38/12 , A61P3/04 , A61P3/10 , A61P25/00 , A61P15/00 , A61P3/06 , A61P9/00 , A61P1/16 , A61P19/02 , A61P35/00 , C07K7/56 , A61P9/10
CPC分类号： C07K14/685 , A61K47/542 , A61K47/545
摘要： The present invention relates to novel peptide compounds which are effective in modulating one or more melanocortin receptor types, to the use of the compounds in therapy, to methods of treatment comprising administration of the compounds to patients in need thereof, and to the use of the compounds in the manufacture of medicaments. The compounds of the invention are of particular interest in relation to the treatment of obesity as well as a variety of diseases or conditions associated with obesity.
摘要翻译： 本发明涉及有效调节一种或多种黑皮质素受体类型，化合物在治疗中的用途的新型肽化合物，包括向有需要的患者施用化合物的方法，以及使用 药物制造中的化合物。 本发明的化合物在治疗肥胖以及与肥胖相关的各种疾病或病症方面特别有意义。
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公开(公告)号：US07517854B2
公开(公告)日：2009-04-14
申请号：US11278014
申请日：2006-03-30
申请人： Kilian Waldemar Conde-Frieboes , Ulrich Sensfuss , Kjeld Madsen , Nils Langeland Johansen , Leif Christensen , Thomas Kruse Hansen , Birgitte Schjellerup Wulff
发明人： Kilian Waldemar Conde-Frieboes , Ulrich Sensfuss , Kjeld Madsen , Nils Langeland Johansen , Leif Christensen , Thomas Kruse Hansen , Birgitte Schjellerup Wulff
IPC分类号： A61K38/12
摘要： Small cyclic peptides of the formula X1-X2-X3-X4-X5-X6-X7-R1 comprising 7-12 amino acid residues are provided. Said peptides are MC4 receptor agonists, and thus useful in the treatment of obesity and related diseases.
摘要翻译： 提供了包含7-12个氨基酸残基的式X1-X2-X3-X4-X5-X6-X7-R1的小环肽。 所述肽是MC4受体激动剂，因此可用于治疗肥胖症和相关疾病。
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公开(公告)号：US20090088388A1
公开(公告)日：2009-04-02
申请号：US12168993
申请日：2008-07-08
申请人： Ulrich Sensfuss , Kilian Waldemar Conde Frieboes , Leif Christensen , Ingrid Vivika Petterson , Thomas Kruse Hansen , Michael Ankersen , Kjeld Madsen
发明人： Ulrich Sensfuss , Kilian Waldemar Conde Frieboes , Leif Christensen , Ingrid Vivika Petterson , Thomas Kruse Hansen , Michael Ankersen , Kjeld Madsen
摘要： Novel cyclic and linear peptides of the formula R1—X—X1—X2—X3—X4—X5—X6—X7—X8—X9—X10—X11—R2 are useful in the treatment of obesity are provided.
摘要翻译： 式R1-X-X1-X2-X3-X4-X5-X6-X7-X8-X9-X10-X11-R2的新型环状和线性肽可用于治疗肥胖症。
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公开(公告)号：US20070244054A1
公开(公告)日：2007-10-18
申请号：US11268268
申请日：2005-11-07
申请人： Ulrich Sensfuss , Kilian Conde Frieboes , Leif Christensen , Ingrid Petterson , Thomas Hansen , Michael Ankersen , Kjeld Madsen
发明人： Ulrich Sensfuss , Kilian Conde Frieboes , Leif Christensen , Ingrid Petterson , Thomas Hansen , Michael Ankersen , Kjeld Madsen
摘要： Novel cyclic and linear peptides of the formula R1—X—X1—X2—X3—X4—X5—X6—X7—X8—X9—X10—X11—R2 are useful in the treatment of obesity are provided.
摘要翻译： 新型的具有式R 1至X 2的环状和线性肽-X -X 2 -X 3 -X 3 - 第4〜第5至第六至第六至第七至第十七至第十七 另外还提供了用于治疗肥胖症的SUP＃9 - 10 - 10 - 11 - 2 - 2。
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