公开(公告)号：US11136401B2

公开(公告)日：2021-10-05

申请号：US15561967

申请日：2016-03-25

申请人： University of Southern California

发明人： Alan L. Epstein ,  Peisheng Hu ,  Jacek K. Pinski

IPC分类号： C07K16/28 ,  G01N33/574 ,  C07K16/30 ,  A61P35/00 ,  A61K35/17 ,  C07K14/725 ,  C07K14/705 ,  A61K35/12 ,  A61K39/00 ,  G01N33/76

摘要： Provided herein are novel anti-LHR chimeric antigen receptor (CAR), cells or compositions comprising the same, vector or plasmid encoding anti-LHR CAR, and methods for producing the same, or using the same for detecting or treating ovarian cancer or prostate cancer. Also provided herein are anti-LHR antibody, compositions comprising the same, nucleic acid sequence encoding the same, and a kit for detecting LHR.

公开(公告)号：US20210403585A1

公开(公告)日：2021-12-30

申请号：US17462987

申请日：2021-08-31

申请人： University of Southern California

发明人： Alan L. Epstein ,  Peisheng Hu ,  Jacek K. Pinski

IPC分类号： C07K16/28 ,  G01N33/574 ,  G01N33/76 ,  C07K16/30 ,  A61P35/00 ,  A61K35/17 ,  C07K14/725 ,  C07K14/705

摘要： Provided herein are novel anti-LHR chimeric antigen receptor (CAR), cells or compositions comprising the same, vector or plasmid encoding anti-LHR CAR, and methods for producing the same, or using the same for detecting or treating ovarian cancer or prostate cancer. Also provided herein are anti-LHR antibody, compositions comprising the same, nucleic acid sequence encoding the same, and a kit for detecting LHR.

公开(公告)号：US20180112003A1

公开(公告)日：2018-04-26

申请号：US15561967

申请日：2016-03-25

申请人： University of Southern California

发明人： Alan L. Epstein ,  Peisheng Hu ,  Jacek K. Pinski

IPC分类号： C07K16/28 ,  C07K14/705 ,  C07K14/725 ,  A61K35/17 ,  C07K16/30 ,  A61P35/00 ,  G01N33/574

CPC分类号： C07K16/2869 ,  A61K35/17 ,  A61K2035/124 ,  A61K2039/505 ,  A61P35/00 ,  C07K14/7051 ,  C07K14/70517 ,  C07K14/70578 ,  C07K16/2809 ,  C07K16/3007 ,  C07K16/3069 ,  C07K2317/24 ,  C07K2317/54 ,  C07K2317/55 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/622 ,  C07K2317/76 ,  C07K2319/02 ,  C07K2319/03 ,  G01N33/57415 ,  G01N33/57434 ,  G01N33/57449 ,  G01N33/76 ,  G01N2800/52

摘要： Provided herein are novel anti-LHR chimeric antigen receptor (CAR), cells or compositions comprising the same, vector or plasmid encoding anti-LHR CAR, and methods for producing the same, or using the same for detecting or treating ovarian cancer or prostate cancer. Also provided herein are anti-LHR antibody, compositions comprising the same, nucleic acid sequence encoding the same, and a kit for detecting LHR.