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1.Polypeptides to Inhibit Epstein Barr Viral Protein BHRF1 and B Cell Lymphoma Family Proteins 有权
Title translation: 多肽抑制爱泼斯坦巴尔病毒蛋白BHRF1和B细胞淋巴瘤家族蛋白公开(公告)号:US20160376333A1
公开(公告)日:2016-12-29
申请号:US15262716
申请日:2016-09-12
Applicant: University of Washington
Inventor: Erick Procko , David Baker , Geoffrey Y. Berguig , Patrick S. Stayton , Yifan Song , Stephanie Ann Berger , Daniel-Adriano Silva
IPC: C07K14/47 , G01N33/574 , A61K47/32 , A61K38/17 , A61K39/395
CPC classification number: A61K47/32 , A61K38/1709 , A61K39/395 , A61K47/645 , C07K14/4747 , C07K16/085 , C07K14/005 , C07K2317/76 , C12N5/0635 , C12N2710/16211 , C12N5/0636 , C12N2710/16234 , C12N7/00 , A61K39/245 , A61K39/12 , A61K35/17 , C07K2317/34 , C07K14/001 , G01N33/56994 , G01N2333/05 , C07K14/4748
Abstract: The present invention provides designed polypeptides that selectively bind to and inhibit Epstein Barr protein BHFR1, and B cell lymphoma family proteins, and are thus useful for treating Epstein Barr-related diseases and cancer.
Abstract translation: 本发明提供了选择性结合并抑制爱泼斯坦巴尔蛋白BHFR1和B细胞淋巴瘤家族蛋白质的设计的多肽,因此可用于治疗爱泼斯坦巴尔相关疾病和癌症。