公开(公告)号：US11284792B2

公开(公告)日：2022-03-29

申请号：US15552437

申请日：2016-03-07

Applicant: UNIVERSITY OF WASHINGTON

Inventor： Ruikang K. Wang ,  Anqi Zhang ,  Qinqin Zhang

IPC: A61B5/00 ,  A61B3/10 ,  A61B5/026 ,  A61B3/00 ,  A61B3/12 ,  A61B3/14 ,  G06T5/00

Abstract: Systems and methods for enhancing quality of a flow image of a sample of a subject are provided. The method comprises acquiring a first flow image from a plurality of first OMAG scans of the sample, and acquiring a structure image from a second OMAG scan of the sample. Data based on pixel intensity values from the flow image and pixel intensity values from the structure image are then plotted onto a graph and from the graph, may be differentiated into a first data group representing static structure signals and a second data group representing flow signals. The method then includes suppressing pixels in the flow image corresponding to the first data group. The flow signal may also be multiplied by a weighting factor to suppress artifacts in the image.

公开(公告)号：US10354378B2

公开(公告)日：2019-07-16

申请号：US15479743

申请日：2017-04-05

Applicant: University of Washington

Inventor： Ruikang K. Wang ,  Chieh-Li Chen ,  Zhongdi Chu ,  Qinqin Zhang

IPC: G06T7/00 ,  G06T7/62 ,  A61B5/00

Abstract: A five-index quantitative analysis of OCT angiograms is disclosed. One method of analyzing an anatomical region of interest of a subject includes acquiring vascular image data from the region of interest and generating a binary vasculature map from the vascular image data. A vessel skeleton map and vessel perimeter map are generated from the binary vasculature map. Based on the three generated maps, a vessel area density, vessel skeleton density, vessel perimeter index, vessel diameter index, and vessel complexity can be determined, in addition to detection of any flow impairment zones in the region of interest. These metrics can be used to detect and assess vascular abnormalities from multiple perspectives.

公开(公告)号：US20170294015A1

公开(公告)日：2017-10-12

申请号：US15479743

申请日：2017-04-05

Applicant: University of Washington

Inventor： Ruikang K. Wang ,  Chieh-Li Chen ,  Zhongdi Chu ,  Qinqin Zhang

IPC: G06T7/00 ,  G06T7/11

CPC classification number: G06T7/0012 ,  G06T7/62 ,  G06T2207/10101 ,  G06T2207/30101

Abstract: A five-index quantitative analysis of OCT angiograms is disclosed. One method of analyzing an anatomical region of interest of a subject includes acquiring vascular image data from the region of interest and generating a binary vasculature map from the vascular image data. A vessel skeleton map and vessel perimeter map are generated from the binary vasculature map. Based on the three generated maps, a vessel area density, vessel skeleton density, vessel perimeter index, vessel diameter index, and vessel complexity can be determined, in addition to detection of any flow impairment zones in the region of interest. These metrics can be used to detect and assess vascular abnormalities from multiple perspectives.