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公开(公告)号：US20100143431A1
公开(公告)日：2010-06-10
申请号：US12445254
申请日：2007-10-02
CPC分类号： C09D5/14 , A01N59/16 , A61M2025/0056 , C02F1/505 , A01N43/08 , A01N2300/00
摘要： The invention relates to the production and use of novel bioactive devices and metallic coatings for example for sterilizing, disinfecting, and decontaminating water or aqueous solutions. The known oligodynamic effect of silver for reducing the amount of germs is thereby improved and increased by combining silver with ruthenium and a vitamin or derivative thereof. The novel properties of these bioactive metal surfaces lead to faster and more efficient killing of microorganisms. Simultaneously, these novel bioactive metal surfaces prevent infestation by microorganisms and attachment or permanent deposition of problematic biomolecules such as for example DNA, RNA, or proteins. A self-cleaning surface is thus obtained, which very quickly and efficiently and over extended periods of time sterilizes water and aqueous solutions when they come in contact with said surface.
摘要翻译： 本发明涉及新型生物活性装置和金属涂层的生产和使用，例如用于消毒，消毒和净化水或水溶液。 因此，通过将银与钌及其维生素或其衍生物结合来改善和增加银的用于减少细菌量的已知的小动力学效应。 这些生物活性金属表面的新特性导致更快更有效地杀死微生物。 同时，这些新的生物活性金属表面防止微生物的侵袭和附着或永久沉积有问题的生物分子，例如DNA，RNA或蛋白质。 因此，获得了自清洁表面，当它们与所述表面接触时，其非常快速且有效地并且延长的时间段使水和水溶液消毒。
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公开(公告)号：US09701848B2
公开(公告)日：2017-07-11
申请号：US12445254
申请日：2007-10-02
CPC分类号： C09D5/14 , A01N59/16 , A61M2025/0056 , C02F1/505 , A01N43/08 , A01N2300/00
摘要： The invention relates to the production and use of novel bioactive devices and metallic coatings for example for sterilizing, disinfecting, and decontaminating water or aqueous solutions. The known oligodynamic effect of silver for reducing the amount of germs is thereby improved and increased by combining silver with ruthenium and a vitamin or derivative thereof. The novel properties of these bioactive metal surfaces lead to faster and more efficient killing of microorganisms. Simultaneously, these novel bioactive metal surfaces prevent infestation by microorganisms and attachment or permanent deposition of problematic biomolecules such as for example DNA, RNA, or proteins. A self-cleaning surface is thus obtained, which very quickly and efficiently and over extended periods of time sterilizes water and aqueous solutions when they come in contact with said surface.
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公开(公告)号：US09795133B2
公开(公告)日：2017-10-24
申请号：US13981548
申请日：2012-01-24
申请人： Thomas Lisowsky , Karlheinz Esser
发明人： Thomas Lisowsky , Karlheinz Esser
IPC分类号： A61K36/53 , A01N37/04 , A01N37/36 , A01N65/00 , A01N65/22 , A01N65/28 , A01N59/16 , A01N63/02
CPC分类号： A01N37/04 , A01N37/36 , A01N59/16 , A01N63/02 , A01N65/00 , A01N65/22 , A01N65/28 , A01N2300/00
摘要： The present invention relates to new, highly efficient anti-microbial compositions comprising essential oils, metal ions, organic acids and detergents. Bacteria-containing samples treated with the complete synergistic disinfecting composition according to the invention (A or B or C or D+O) do not show any living cell colonies, indicating that under these conditions all microorganisms were killed. Thus it is proven that the synergistic mixtures of the compounds according to the invention show a very effective antimicrobial effect.
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公开(公告)号：US08557265B2
公开(公告)日：2013-10-15
申请号：US12452295
申请日：2008-06-27
申请人： Barbara Krug , Sven Eggerstedt , Christiane Ostermeyer , Thomas Lisowsky , Karlheinz Esser , Frank Büger , Richard Bloss
发明人： Barbara Krug , Sven Eggerstedt , Christiane Ostermeyer , Thomas Lisowsky , Karlheinz Esser , Frank Büger , Richard Bloss
CPC分类号： A61K31/352 , A01N59/00 , A61K9/0014 , A61K31/24 , A61K33/00 , A61K45/06 , A01N25/30 , A01N2300/00 , A61K2300/00
摘要： The invention relates to the use of a composition comprising a vitamin, a metal ion, and a surfactant, as a therapeutic agent or disinfectant. The composition has been known as a decontaminant because the same efficiently decomposes DNA. It has now been possible to demonstrate that the agent has surprisingly good compatibility while having a wide-ranging disinfecting effect and is therefore also suitable for other purposes, e.g., for disinfecting or dressing wounds.
摘要翻译： 本发明涉及包含维生素，金属离子和表面活性剂的组合物作为治疗剂或消毒剂的用途。 该组合物已知为净化剂，因为同样有效地分解DNA。 现在可以证明该试剂具有惊人的良好的相容性，同时具有广泛的消毒作用，因此也适用于其它目的，例如消毒或敷料伤口。
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5.发明申请公开(公告)号：US20120107415A1
公开(公告)日：2012-05-03
申请号：US13140436
申请日：2009-11-14
申请人： Thomas Lisowsky , Sven Eggerstedt , Richard Bloss , Christiane Ostermeyer , Karlheinz Esser , Frank Bürger , Barbara Krug , Yvonne Feil , Kai-Martin Mueller , Delphine Haase
发明人： Thomas Lisowsky , Sven Eggerstedt , Richard Bloss , Christiane Ostermeyer , Karlheinz Esser , Frank Bürger , Barbara Krug , Yvonne Feil , Kai-Martin Mueller , Delphine Haase
IPC分类号： A01N31/02 , A01N33/12 , A01N35/02 , A01N31/08 , A01N31/10 , A01N31/16 , A01N27/00 , A01N59/00 , A01N59/14 , A01N37/16 , A61K31/045 , A61K31/047 , A61K31/19 , A61K31/14 , A61K31/11 , A61P31/00 , A01P1/00 , A01N37/36
CPC分类号： A01N59/16 , A01N43/08 , A01N59/20 , A01N31/02 , A01N33/12 , A01N37/36 , A01N31/08 , A01N2300/00
摘要： The invention relates to a novel combined disinfection and decontamination agent comprising at least one vitamin, at least one metal ion, at least one active-surface compound, and at least one further antimicrobial active substance. The agent according to the invention surprisingly shows nearly complete nucleic acid disintegration in addition to an improved disinfectant effect. The agent can be successfully used as a combined decontamination and disinfection agent for skin, mucous membranes, hands, wounds, and/or hair, and instruments and surfaces of all kinds.
摘要翻译： 本发明涉及包含至少一种维生素，至少一种金属离子，至少一种活性表面化合物和至少一种其它抗微生物活性物质的新型组合消毒和去污剂。 根据本发明的药剂除了改进的消毒剂效果之外令人惊讶地显示出几乎完全的核酸分解。 该试剂可以成功地用作皮肤，粘膜，手，伤口和/或头发以及各种仪器和表面的组合去污和消毒剂。
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6.发明授权公开(公告)号：US08999399B2
公开(公告)日：2015-04-07
申请号：US13140436
申请日：2009-11-14
申请人： Thomas Lisowsky , Sven Eggerstedt , Richard Bloss , Christiane Ostermeyer , Karlheinz Esser , Frank Bürger , Barbara Krug , Yvonne Feil , Kai-Martin Mueller , Delphine Haase
发明人： Thomas Lisowsky , Sven Eggerstedt , Richard Bloss , Christiane Ostermeyer , Karlheinz Esser , Frank Bürger , Barbara Krug , Yvonne Feil , Kai-Martin Mueller , Delphine Haase
IPC分类号： A01N31/02 , A01N33/12 , A01N35/02 , A01N31/08 , A01N31/10 , A01N31/16 , A01N27/00 , A01N59/00 , A01N59/14 , A01N37/16 , A61K31/045 , A61K31/047 , A61K31/19 , A61K31/14 , A61K31/11 , A61P31/00 , A01N37/36 , A01N59/16 , A01N43/08 , A01N59/20
CPC分类号： A01N59/16 , A01N43/08 , A01N59/20 , A01N31/02 , A01N33/12 , A01N37/36 , A01N31/08 , A01N2300/00
摘要： The invention relates to a novel combined disinfection and decontamination agent comprising at least one vitamin, at least one metal ion, at least one active-surface compound, and at least one further antimicrobial active substance. The agent according to the invention surprisingly shows nearly complete nucleic acid disintegration in addition to an improved disinfectant effect. The agent can be successfully used as a combined decontamination and disinfection agent for skin, mucous membranes, hands, wounds, and/or hair, and instruments and surfaces of all kinds.
摘要翻译： 本发明涉及包含至少一种维生素，至少一种金属离子，至少一种活性表面化合物和至少一种其它抗微生物活性物质的新型组合消毒和去污剂。 根据本发明的药剂除了改进的消毒剂效果之外令人惊讶地显示出几乎完全的核酸分解。 该试剂可以成功地用作皮肤，粘膜，手，伤口和/或头发以及各种仪器和表面的组合去污和消毒剂。
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公开(公告)号：US20130302434A1
公开(公告)日：2013-11-14
申请号：US13981548
申请日：2012-01-24
申请人： Thomas Lisowsky , Karlheinz Esser
发明人： Thomas Lisowsky , Karlheinz Esser
CPC分类号： A01N37/04 , A01N37/36 , A01N59/16 , A01N63/02 , A01N65/00 , A01N65/22 , A01N65/28 , A01N2300/00
摘要： The present invention relates to new, highly efficient anti-microbial compositions comprising essential oils, metal ions, organic acids and detergents. Bacteria-containing samples treated with the complete synergistic disinfecting composition according to the invention (A or B or C or D+O) do not show any living cell colonies, indicating that under these conditions all microorganisms were killed. Thus it is proven that the synergistic mixtures of the compounds according to the invention show a very effective antimicrobial effect.
摘要翻译： 本发明涉及包含精油，金属离子，有机酸和洗涤剂的新型高效抗微生物组合物。 用根据本发明的完全协同消毒组合物（A或B或C或D + O）处理的含细菌样品不显示任何活细胞集落，表明在这些条件下，所有的微生物被杀死。 因此，证明了根据本发明的化合物的协同混合物显示出非常有效的抗微生物效果。
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8.发明申请公开(公告)号：US20100119566A1
公开(公告)日：2010-05-13
申请号：US12452295
申请日：2008-06-27
申请人： Barbara Krug , Sven Eggerstedt , Christiane Ostermeyer , Thomas Lisowsky , Karlheinz Esser , Frank Bürger , Richard Bloss
发明人： Barbara Krug , Sven Eggerstedt , Christiane Ostermeyer , Thomas Lisowsky , Karlheinz Esser , Frank Bürger , Richard Bloss
CPC分类号： A61K31/352 , A01N59/00 , A61K9/0014 , A61K31/24 , A61K33/00 , A61K45/06 , A01N25/30 , A01N2300/00 , A61K2300/00
摘要： The invention relates to the use of a composition comprising a vitamin, a metal ion, and a surfactant, as a therapeutic agent or disinfectant. The composition has been known as a decontaminant because the same efficiently decomposes DNA. It has now been possible to demonstrate that the agent has surprisingly good compatibility while having a wide-ranging disinfecting effect and is therefore also suitable for other purposes, e.g., for disinfecting or dressing wounds.
摘要翻译： 本发明涉及包含维生素，金属离子和表面活性剂的组合物作为治疗剂或消毒剂的用途。 该组合物已知为净化剂，因为同样有效地分解DNA。 现在可以证明该试剂具有惊人的良好的相容性，同时具有广泛的消毒作用，因此也适用于其它目的，例如消毒或敷料伤口。
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9.发明申请Decontamination solution and its use for denaturation, modification, degradation, solubilisation and removal of proteins, nucleic acid molecules and microorganisms 审中-公开去污溶液及其用于蛋白质，核酸分子和微生物的变性，改性，降解，增溶和去除的用途公开(公告)号：US20090028961A1
公开(公告)日：2009-01-29
申请号：US11913094
申请日：2006-05-02
摘要： The invention concerns a three component system comprising surface-active substances, vitamins and metal ions for efficient destruction and removal of contaminating proteins, nucleic acids and microorganisms from surfaces like for example laboratory benches, floors, equipment and instruments. These non-corrosive and non-toxic solutions for removal of proteins, nucleic acids and microorganisms are applied by spraying, rubbing or immersion of contaminated surfaces thereby destroying, solubilizing inactivating and removing proteins and nucleic acids. In that way also microorganisms are killed with high efficiency and at the same time all genetic information is inactivated.
摘要翻译： 本发明涉及包含表面活性物质，维生素和金属离子的三组分体系，用于有效地破坏和去除表面上的污染蛋白质，核酸和微生物，例如实验室台，地板，设备和仪器。 这些用于去除蛋白质，核酸和微生物的非腐蚀性和无毒性溶液通过喷洒，摩擦或浸渍受污染的表面进行施用，从而破坏，增溶灭活和去除蛋白质和核酸。 这样也可以高效杀死微生物，同时所有遗传信息都被灭活。
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