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公开(公告)号：US11890319B2
公开(公告)日：2024-02-06
申请号：US16478696
申请日：2018-01-18
申请人： VISTERRA, INC.
发明人： Zachary Shriver , Obadiah Joseph Plante , Kai Li , Karthik Viswanathan , James C. Delaney , Boopathy Ramakrishnan , Andrew M. Wollacott
CPC分类号： A61K38/1729 , A61K47/6811 , A61K47/6815 , A61K47/6889 , A61P31/04 , C07K16/1203 , C07K2317/51 , C07K2317/515 , C07K2317/522 , C07K2317/524 , C07K2317/526
摘要： Antibody molecule-drug conjugates (ADCs) that specifically bind to lipopolysaccharides (LPS) are disclosed. The antibody molecule-drug conjugates can be used to treat, prevent, and/or diagnose bacterial infections and related disorders.
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公开(公告)号：US20230348614A1
公开(公告)日：2023-11-02
申请号：US18058334
申请日：2022-11-23
申请人： VISTERRA, INC.
CPC分类号： C07K16/2896 , A61K47/6849 , C07K2317/52 , C07K2317/55 , C07K2317/732 , C07K2317/734 , C07K2317/92 , C07K2317/94
摘要： Antibody molecules that specifically bind to CD138 in a tumor microenvironment (e.g., at acidic pH) are disclosed. The antibody molecules can be used to treat, prevent, and/or diagnose disorders, such as multiple myeloma.
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公开(公告)号：US11773179B2
公开(公告)日：2023-10-03
申请号：US17147842
申请日：2021-01-13
申请人： Visterra, Inc.
发明人： Karthik Viswanathan , Brian Booth , Boopathy Ramakrishnan , Andrew Wollacott , Gregory Babcock , Zachary Shriver
CPC分类号： C07K16/2896 , A61K2039/505 , C07K2317/31 , C07K2317/76
摘要： Antibody molecules that specifically bind to C5aR1 are disclosed. The antibody molecules can be used to treat, prevent, and/or diagnose disorders, such as ANCA-vasculitis.
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公开(公告)号：US11168131B2
公开(公告)日：2021-11-09
申请号：US15348436
申请日：2016-11-10
申请人： VISTERRA, INC.
发明人： Obadiah Joseph Plante , James C. Delaney , Karthik Viswanathan , Boopathy Ramakrishnan , Zachary Holmes Shriver , Andrew M. Wollacott
IPC分类号： C07K16/12 , C07K7/08 , C07K14/00 , C07K7/06 , A61K47/68 , A61K38/10 , A61K38/16 , A61K39/40 , A61K45/06 , C07K16/44 , A61K39/00
摘要： Antibody molecule-drug conjugates (ADCs) that specifically bind to lipopolysaccharides (LPS) are disclosed. The antibody molecule-drug conjugates can be used to treat, prevent, and/or diagnose bacterial infections and related disorders.
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公开(公告)号：US10981982B2
公开(公告)日：2021-04-20
申请号：US16912085
申请日：2020-06-25
申请人： VISTERRA, INC.
发明人： James R. Myette , Zachary Holmes Shriver , Karthik Viswanathan , Andrew M. Wollacott , Hedy Adari-Hall , Boopathy Ramakrishnan , Gregory Babcock
IPC分类号： C07K16/24 , C07K16/28 , A61K39/395 , A61K45/06 , A61K39/00
摘要： Antibody molecules that specifically bind to APRIL are disclosed. The antibody molecules can be used to treat, prevent, and/or diagnose disorders, such as IgA nephropathy.
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公开(公告)号：US10954296B2
公开(公告)日：2021-03-23
申请号：US16898024
申请日：2020-06-10
申请人： VISTERRA, INC.
发明人： James R. Myette , Zachary Holmes Shriver , Karthik Viswanathan , Andrew M. Wollacott , Hedy Adari-Hall , Boopathy Ramakrishnan , Gregory Babcock
IPC分类号： A61K39/395 , A61K39/00 , C07K16/24 , A61K45/06 , C07K16/28
摘要： Antibody molecules that specifically bind to APRIL are disclosed. The antibody molecules can be used to treat, prevent, and/or diagnose disorders, such as IgA nephropathy.
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公开(公告)号：US20200331995A1
公开(公告)日：2020-10-22
申请号：US16912131
申请日：2020-06-25
申请人： VISTERRA, INC.
发明人： James R. Myette , Zachary Holmes Shriver , Karthik Viswanathan , Andrew M. Wollacott , Hedy Adari-Hall , Boopathy Ramakrishnan , Gregory Babcock
IPC分类号： C07K16/24 , A61K39/395 , A61K45/06 , C07K16/28
摘要： Antibody molecules that specifically bind to APRIL are disclosed. The antibody molecules can be used to treat, prevent, and/or diagnose disorders, such as IgA nephropathy.
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公开(公告)号：US20190100588A1
公开(公告)日：2019-04-04
申请号：US16149854
申请日：2018-10-02
申请人： VISTERRA, INC.
发明人： Bharat Chaganty , Boopathy Ramakrishnan , Hedy Adari-Hall , Karthik Viswanathan , James R. Myette , Zachary Shriver
IPC分类号： C07K16/28 , A61P35/00 , C12N15/62 , A61K39/395
摘要： Antibody molecules that specifically bind to CD138 are disclosed. The antibody molecules can be used to treat, prevent, and/or diagnose disorders, such as multiple myeloma.
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公开(公告)号：US20240342300A1
公开(公告)日：2024-10-17
申请号：US18435809
申请日：2024-02-07
申请人： VISTERRA, INC.
发明人： Karthik Viswanathan , Kenneth Douglas Johnson , Obadiah Joseph Plante , James C. Delaney , Tyree J. Koch , Hamid Tissire , Andrew M. Wollacott , Boopathy Ramakrishnan
CPC分类号： A61K47/6811 , A61K45/06 , A61P31/04 , C07K16/1214 , C07K2317/24
摘要： Antibody molecule-drug conjugates (ADCs) that specifically bind to lipopolysaccharides (LPS) are disclosed. The antibody molecule-drug conjugates can be used to treat, prevent, and/or diagnose bacterial infections and related disorders.
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公开(公告)号：US12098178B2
公开(公告)日：2024-09-24
申请号：US17541989
申请日：2021-12-03
发明人： Scott Moore Carlson , Gregory Babcock , Zachary Shriver , Boopathy Ramakrishnan , Thiago de Jesus Borges , Leonardo Vidal Riella
摘要： IL-2 agents that comprise IL-2 variants are disclosed as well as methods, compositions, and uses thereof. The IL-2 agents described herein can be used to treat and/or prevent various disorders and conditions.
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